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Cardium's InnerCool Reports on Expanding Use of Therapeutic Hypothermia
Date:1/29/2009

32 degrees Celsius to 34 degrees Celsius for at least 12 to 24 hours. Most experts currently recommend cooling for at least 24 hours. Although data support cooling to 32 degrees Celsius to 34 degrees Celsius, the optimal temperature has not been determined. Induced hypothermia might also benefit unconscious adult patients with spontaneous circulation after out-of-hospital cardiac arrest from a nonshockable rhythm or in-hospital cardiac arrest. Although the optimal timing of initiation has not been defined clinically, current consensus is to initiate cooling as soon as possible."

Temperature modulation therapy to safely and effectively cool patients represents an important new tool that is beginning to be utilized for protecting the brain from ischemia, especially in post-cardiac arrest patients who are at higher risk of brain tissue damage due to the prolonged lack of blood flow. With the increase in survival of cardiac arrest victims resulting from the advent of automated external defibrillators, cooling patients is the next logical therapeutic approach especially in light of the large body of supporting scientific literature, and guidelines issued by the AHA and the International Liaison Committee on Resuscitation recommending that cardiac arrest victims be treated with induced hypothermia.

Cardiology News and Other Reports

Therapeutic hypothermia has been increasingly in the news and is now beginning to become a standard of care in a growing number of hospitals and emergency medical centers. In an article entitled "Cooling for Cardiac Arrest Catches On" in Cardiology News, Mary Ann Peberdy, Professor of Medicine and Emergency Medicine at Virginia Commonwealth University in Richmond summarized these trends, noting that "there has been a major shift in the use of therapeutic hypothermia. We've seen a substantial increase in interest so that at the start of 2009 there is gen
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SOURCE Cardium Therapeutics
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