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Cardiogenesis Announces Preliminary Results Combining TMR + Platelet Rich Plasma (PRP)
Date:6/18/2008

IRVINE, Calif., June 18 /PRNewswire-FirstCall/ -- Cardiogenesis Corporation (Pink Sheets: CGCP), a leading developer of surgical products for cardiac revascularization today announced an upcoming scientific presentation that describes the use of combining transmyocardial revascularization (TMR) with platelet rich plasma (PRP).

The presentation titled "Intramyocardial Injection of Autologous Platelet Rich Plasma combined with Transmyocardial Revascularization" will be presented by Kurt E. Wehberg, MD of Peninsula Regional Medical Center (Salisbury, Maryland) at the 34th annual meeting of the Western Thoracic Surgical Association on June 28, 2008 in Kona, Hawaii. The abstract of the presentation is available at http://www.westernthoracic.org/Abstracts/2008/BC8.html.

Dr. Wehberg will be presenting on a group of 25 consecutive patients treated with the Cardiogenesis holmium: YAG Laser TMR System. Eleven patients in the series received a combination therapy of TMR with an intramyocardial injection of autologous PRP, which is a concentration of platelets, white blood cells and circulating stem cells from the patients' own peripheral blood. At six months, a blinded angina assessment demonstrated:

-- Both groups achieved significant angina relief.

-- The TMR + PRP group had a lower average angina score (0.4 vs 1.7,

p=0.07) than the TMR alone group, and were more likely to be angina

free (71% vs 23%, p=0.04).

-- Ejection fraction (EF) improved in the TMR + PRP group (+9.0% vs.

-2.0%, p=0.07) compared to the TMR group.

The authors conclude, "These preliminary results suggest that combining intramyocardial injection of PRP with TMR may be more efficacious at relieving angina and improving myocardial function than TMR alone."

Richard Lanigan, President of Cardiogenesis, noted, "The results that Dr. Wehberg wil
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SOURCE Cardiogenesis Corporation
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