Navigation Links
Cardiff scientists bid to develop anthrax vaccine to counteract world bioterrorism threat
Date:9/17/2012

A team of Cardiff University scientists is leading new research to develop a vaccine against anthrax to help counteract the threat of bioterrorism.

Working with scientists from the Republic of Georgia, Turkey and the USA, Professor Les Baillie from Cardiff University's School of Pharmacy and Pharmaceutical Sciences is leading a NATO project to tackle the potential misuse of anthrax.

"Currently the majority of the world's population is susceptible to infection with Bacillus anthracis the bacterium which causes anthrax," according to Professor Baillie, who leads the multi-national research collaboration.

"The US postal attacks in 2001 highlighted the vulnerability of civilian populations and brought home the need to develop effective, rapid, robust medical countermeasures to combat the threat posed by terrorist use of this organism," he added.

It is the growing concern over the threat posed by bioterrorism that has prompted world authorities like NATO through its Science for Peace and Security Programme to support efforts to develop more effective vaccines and medical countermeasures.

Efforts have so far been hampered by the fact that cases of naturally acquired human infection are rare in NATO countries. As a consequence, researchers have been forced to employ animal models to develop new vaccines.

The problem with this approach is the immune responses of animals and humans differ and as a consequence human clinical trials represent an essential element in confirming the efficacy of any new vaccine.

Such trials require access to several thousand volunteers at risk of infection and as such would be almost impossible to perform in Western Europe or the US.

In contrast anthrax represents a significant disease of animals and humans in the Cacuses and Central Asia. For this reason researchers from the UK and US have joined with colleagues from Turkey and the former Soviet republic of Georgia to tackle the problem.

Professor Baillie added: "These unique resources, combined with the expertise of NATO researchers offers us an unparalleled opportunity."

The outputs of this study are expected to underpin the development of future vaccines capable of conferring broad-spectrum, robust protection following minimal dosing.

Such vaccines would impact on two levels, locally they would directly improve the life of workers at risk of contracting anthrax such as farmers, and globally they would contribute to the protection of citizens from the use of anthrax as an agent of bio-terrorism.

An additional benefit of this work will be the establishment of a research centre in Georgia which will support infectious disease research and ultimately improve the lives of all of the people in the region.


'/>"/>

Contact: Professor Les Baillie
baillieL@cf.ac.uk
029-208-75535
Cardiff University
Source:Eurekalert

Related medicine news :

1. Scientists solving the mystery of human consciousness
2. Scientists uncover multiple faces of deadly breast cancer
3. Scientists identify major source of cells defense against oxidative stress
4. Scientists tailor cell surface targeting system to hit organelle ZIP codes
5. Scientists rewrite rulebook on breast cancer in landmark global study
6. Warwick scientists uncover how checkpoint proteins bind chromosomes
7. NIH scientists link quickly spreading gene to Asian MRSA epidemic
8. Joslin scientists identify important mechanism that affects the aging process
9. Scripps Research scientists show how memory B cells stay in class to fight different infections
10. Scientists Map Melanomas Genome
11. A*STAR scientists discover switch to boost anti-viral response to fight infectious diseases
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... Overland Park, KS (PRWEB) , ... June 27, 2016 , ... ... leader in retailers of Eyeglasses . , Millions of individuals in the United ... life, eyeglasses have become a way to both correct vision and make a fashion ...
(Date:6/26/2016)... ... June 26, 2016 , ... Brent Kasmer, a legally blind and certified personal trainer ... through a fitness app. The fitness app plans to fix the two major problems leading ... a one size fits all type program , They don’t eliminate all the ...
(Date:6/25/2016)... ... June 25, 2016 , ... "With 30 hand-drawn hand gesture animations, FCPX users ... - CEO of Pixel Film Studios. , ProHand Cartoon’s package transforms over 1,300 ... Pro X . Simply select a ProHand generator and drag it above media or ...
(Date:6/25/2016)... , ... June 25, 2016 , ... Conventional wisdom preaches ... success. In terms of the latter, setting the bar too high can result in ... than just slow progress toward their goal. , Research from PsychTests.com ...
(Date:6/24/2016)... ... June 24, 2016 , ... The Pulmonary Hypertension Association ... it will receive two significant new grants to support its work to advance ... 25th anniversary by recognizing patients, medical professionals and scientists for their work in ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016  In a startling report released ... failing their residents by lacking a comprehensive, proven plan to eliminate ... a definitive ranking of how states are tackling the worst drug ... only four states – Kentucky , ... Vermont . Of the 28 failing states, three – ...
(Date:6/23/2016)... , June 23, 2016 Bracket , a ... its next generation clinical outcomes platform, Bracket eCOA (SM) ... on June 26 – 30, 2016 in Philadelphia ... electronic Clinical Outcome Assessment product of its kind to fully ... Bracket eCOA 6.0 is a flexible platform for ...
(Date:6/23/2016)... -- Guerbet announced today that it has been named a ... One of 12 suppliers to receive the ... of Premier members through exceptional local customer service and ... lower costs. "We ... customer service from Premier," says Massimo Carrara , ...
Breaking Medicine Technology: