Navigation Links
Cardiac stem cell trial seeks to treat some heart attack patients
Date:9/30/2009

Researchers at UCSF Medical Center have begun enrollment for an early-stage clinical trial to evaluate the safety and efficacy of an adult stem cell therapy for patients who have just experienced their first acute myocardial infarction, or heart attack. The trial is part of a multi-center national study.

The cells used, known as mesenchymal stem cells, were obtained from the bone marrow of healthy adult donors. Depending on their location in the body, mesenchymal stem cells give rise to bone, cartilage, fat, muscle and connective tissue.

The experimental therapy is intended to combat the symptoms related to heart damage that continue to develop following a heart attack, including low pumping capacity, inflammation and increased scar tissue. Although the exact mechanisms of the stem cells' actions in this setting are not yet known, previous studies have suggested that they could reduce the amount of scar tissue and inflammation caused by heart attack.

A previous UCSF study on the impact of bone marrow-derived stem cells on heart attacks in mice provided evidence that stem cells work by assisting in tissue repair on the cellular level, resulting is less damage and improved function.

The new clinical trial is the first stem cell clinical trial in cardiology at UCSF.

"This is an important and exciting step for physicians and scientists seeking to translate research into beneficial treatments for patients," said Yerem Yeghiazarians, MD, co-director of the Adult Cardiac Catheterization Laboratory, director of the UCSF Translational Cardiac Stem Cell Program and lead investigator of the cardiac stem cell study.

"Many of us have been working for a long time to have a therapy for patients that could improve organ damage at the basic level," he added. "UCSF is one of the fastest hospitals in the nation at treating heart attack with angioplasty, according to the National Cardiovascular Data Registry. We are hoping
'/>"/>

Contact: Lauren Hammit
lhammit@pubaff.ucsf.edu
415-476-2557
University of California - San Francisco
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. The ScottCare Corporation Completes Acquisition of Rozinn Electronics, a Leading Manufacturer of Cardiac Diagnostic Products
2. Corporate and Political PR Pro to Lead Sudden Cardiac Arrest Association
3. Family History Has Strong Effect on Cardiac Risk
4. American Heart Association Surgical Supplement Journal Report: Appropriate Hospital Discharge System Can Prevent Future Cardiac Events
5. Cardiac Science to Present at the UBS Global Life Sciences Conference
6. Cardiac Science Applauds Mass AED Training of Pittsburgh Educators
7. Guidelines help patients reduce risk of cardiac event before surgery
8. Cardiac Science Named to Deloittes Technology Fast 50 for Washington State
9. Cleveland Clinic and The Larry King Cardiac Foundation Partner to Provide Heart Surgery to Those in Need
10. Cardiac Science Releases New Cardiac Rehabilitation System
11. Cardiac Artery Trouble Boosts Family Heart Risk
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... (PRWEB) January 22, 2015 The Incredible Bulk ... Ben Pakulski to increase lean muscle by up to 30lbs ... caught the attention of HealthyandFitZone.com’s Stan Stevenson, prompting an investigative ... it is a step-by-step, scientific diet formula that allows the ...
(Date:1/22/2015)... 2015 The federal court overseeing thousands of ... Court, Southern District of West Virginia has upheld a $2 ... first bellwether trial. In an Order dated January 21st, the ... finding that C.R. Bard had not proven a miscarriage of ...
(Date:1/22/2015)... released a new blog post explaining the main features of ... Auto insurance quotes help many drivers find the best coverage ... an agent or visit an agency for price information. These ... http://autocarinsurancebest.com/ . , Every business who relies heavily on transportation ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 A ... Sports Medicine flagship journal Medicine & Science in ... before exercise may help reduce gastrointestinal (GI) problems ... , Participants in the double-blind, placebo-controlled study ...
(Date:1/22/2015)... Four years since the release of their debut recording Love is ... Avasa & Matthew Love – the duo are pleased to announce ... White Swan Records on February 24, 2015. , THE ROAD offers ... to all of us to walk out of the mire of ...
Breaking Medicine News(10 mins):Health News:The Incredible Bulk: Review Examining Ben Pakulski’s Brand New Bulking Muscle Building Diet Program Released 2Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 2Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 3Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 4Health News:Commercial Auto Insurance Provides Several Important Features! 2Health News:Study Shows Kyowa Hakko’s L-Citrulline May Help Reduce Gastrointestinal Injury During Strenuous Exercise 2Health News:Study Shows Kyowa Hakko’s L-Citrulline May Help Reduce Gastrointestinal Injury During Strenuous Exercise 3Health News:THE ROAD by Avasa & Matthew Love -- A New Album 2Health News:THE ROAD by Avasa & Matthew Love -- A New Album 3Health News:THE ROAD by Avasa & Matthew Love -- A New Album 4
... breast cancer researcher and assistant member at Moffitt ... General Electric,s $100 million healthymagination Challenge to develop ... to determine if they are predisposed to develop ... grant awarding initiative focuses on "finding new ideas ...
... Researchers at Moffitt Cancer Center and colleagues have ... strong concerns about their ability to have children ... health-related quality-of-life survey tools used to elicit answers ... these concerns. Parents, who often answer survey questions ...
... Center have placed new emphasis on gathering data on cancer ... focus is on gathering and using that data to develop ... treatment and for cancer survivors. Much of the quality ... in Moffitt,s Department of Health Outcomes & Behavior. "Among ...
... , FRIDAY, April 27 (HealthDay News) -- People with chronic ... be able to sleep better, according to a new study. ... basis. The study included 214 people with chronic jaw ... patients were white females, whose average age was 34. ...
... April 27 (HealthDay News) -- People undergoing outpatient surgery should ... to a new study that finds the risk is higher ... older or obese. The University of Michigan researchers found ... clot after outpatient surgery. More than 60 percent of ...
... and Rebecca Moores Professor of Psychology, has earned the ... symbol of overall career excellence and the highest honor ... carries a cash prize of $10,000. "The Farfel ... that we may have as professionals, as mentors, teachers, ...
Cached Medicine News:Health News:Moffitt researcher awarded GE grant to develop tool to detect breast cancer metastasis genetic risks 2Health News:Moffitt researchers find adolescents with cancer concerned about their future reproductive health 2Health News:Moffitt researchers find adolescents with cancer concerned about their future reproductive health 3Health News:Moffitt Cancer Center researchers: Quality of life as important as quantity of life 2Health News:Moffitt Cancer Center researchers: Quality of life as important as quantity of life 3Health News:Adjusting Your Attitude About Chronic Pain May Help You Sleep 2Health News:Blood Clot Risk for Outpatients Needs More Attention: Study 2Health News:Neuropsychologist receives University of Houston's highest faculty honor 2Health News:Neuropsychologist receives University of Houston's highest faculty honor 3
(Date:1/23/2015)... 2015  iMD Companies, Inc. (ICBU) has repositioned itself as a ... grab a foothold in the hydroponic, hemp and medical marijuana ... presence in the sector, and recently partnering with the Chippewa ... and medical marijuana, iMD is committing to bring its vision ...
(Date:1/23/2015)...  Mallinckrodt plc (NYSE: MNK ) announced today ... repurchase program. The open-ended authorization permits the company to ... shares. "Funding additional initiatives and seeking ... continue to pursue a range of focused growth strategies," ...
(Date:1/22/2015)... 22, 2015  BiOptix is pleased to announce the appointment ... of Chemistry and Biochemistry. Scott joins the company after previous ... Amgen throughout the course of his nearly 20 year ... is a nationally recognized thought leader in the biosensor ...
Breaking Medicine Technology:iMD Companies Poised to Make Impact in Multi-Billion Dollar Medical Marijuana Sector With Recent Investments and Strategic Partnerships 2Mallinckrodt plc Announces Share Repurchase Program 2Mallinckrodt plc Announces Share Repurchase Program 3Mallinckrodt plc Announces Share Repurchase Program 4BiOptix Expands Leadership Team with the Appointment of Dr. Scott Klakamp as Vice President of Chemistry and Biochemistry 2
... BETHESDA, Md., April 14 Micromet, Inc.,(Nasdaq: ... novel, proprietary,antibodies for the treatment of cancer, ... meeting of the American Association for,Cancer Research ... that commercial,anti-cancer antibodies trastuzumab (Herceptin(R); Genentech, Roche),cetuximab ...
... the, Tumor Suppressor P53 Inhibited Tumor Growth Synergistically in Preclinical ... ... 14 ,Peregrine Pharmaceuticals, Inc. (Nasdaq: PPHM ) announced today that ... 2008 Annual Meeting of the American Association for Cancer Research,(AACR) further ...
Cached Medicine Technology:Micromet Demonstrates That the Antibodies in Commercial Products Herceptin, Erbitux, Vectibix and Xolair Can Be Converted Into Highly Potent, T Cell- Engaging BiTE Antibodies 2Micromet Demonstrates That the Antibodies in Commercial Products Herceptin, Erbitux, Vectibix and Xolair Can Be Converted Into Highly Potent, T Cell- Engaging BiTE Antibodies 3Micromet Demonstrates That the Antibodies in Commercial Products Herceptin, Erbitux, Vectibix and Xolair Can Be Converted Into Highly Potent, T Cell- Engaging BiTE Antibodies 4Micromet Demonstrates That the Antibodies in Commercial Products Herceptin, Erbitux, Vectibix and Xolair Can Be Converted Into Highly Potent, T Cell- Engaging BiTE Antibodies 5Preclinical Study Presented at AACR Annual Meeting Shows Broad Anti-Cancer Potential of Peregrine's anti-PS Vascular Targeting Antibodies 2Preclinical Study Presented at AACR Annual Meeting Shows Broad Anti-Cancer Potential of Peregrine's anti-PS Vascular Targeting Antibodies 3Preclinical Study Presented at AACR Annual Meeting Shows Broad Anti-Cancer Potential of Peregrine's anti-PS Vascular Targeting Antibodies 4
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: