Navigation Links
Cardiac Deaths May Lead to Shortage of Donor Livers

FRIDAY, Jan. 11 (HealthDay News) -- The number of donor livers that aren't being used for transplants in the United States is increasing due to declining quality of the donated organs, and could lead to a shortage of livers available for transplant, a new study finds.

The primary cause of the decrease in liver donor quality is donation after cardiac death (when blood circulation ceases), but it is also due to donors who are older, have diabetes or are overweight.

For the study, researchers analyzed U.S. data on more than 107,000 deceased organ donors between 1988 and 2010. The number of unused livers declined from 66 percent in 1988 to 15 percent in 2004, and then rose to 21 percent in 2010, the investigators found.

Nonuse of donated livers was independently linked to donation after cardiac death, older donor age, donor diabetes and donors being overweight or obese, according to the study, which appears in the January issue of the journal Liver Transplantation.

"Our findings show nonuse of livers for transplantation is steadily rising, and is primarily due to donation after cardiac death," Dr. Eric Orman, of the University of North Carolina School of Medicine, in Chapel Hill, said in a journal news release. "If these trends continue, a significant decline in liver transplant availability would be inevitable."

"For patients with end-stage liver disease, transplantation is the only option for extending life, but organ availability places constraints on the transplant community," Orman noted. "One of the methods to increase the donor pool is to include donors with less than ideal health status -- those with fatty livers, older donors and donation after cardiac death."

Dr. Anton Skaro, of the Feinberg School of Medicine at Northwestern University in Chicago, wrote an accompanying editorial. He pointed out that livers donated after cardiac death have higher complication and failure rates. These organs, however, should be encouraged for patients who face poor outcomes if they remain on the liver transplant waiting list, he noted.

More information

The U.S. National Institute of Diabetes and Digestive and Kidney Diseases has more about liver transplantation.

-- Robert Preidt

SOURCE: Liver Transplantation, news release, Jan. 10, 2013

Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Survival Tripled for Hospitalized U.S. Kids With Cardiac Arrest
2. Predicting risk of arrhythmias and sudden cardiac death: Theres a computer model for that
3. Discovery in Ghent could improve screening for sudden cardiac death
4. General thoracic surgeons emerge as leading providers of complex, noncardiac thoracic surgery
5. AHA awards Loyola more than $60,000 for cardiac research
6. Cardiac Screening for All Young Athletes Carries Big Price Tag: Study
7. Preventive screening for sudden cardiac death in young athletes debated
8. Patients More Likely to Survive In-Hospital Cardiac Arrest Today: Study
9. Body Temperature May Matter After Cardiac Arrest
10. Fish Oil Wont Prevent Irregular Heartbeat After Cardiac Surgery: Study
11. Losing Weight May Lower Cardiac Risks
Post Your Comments:
Related Image:
Cardiac Deaths May Lead to Shortage of Donor Livers
(Date:11/26/2015)... (PRWEB) , ... November 26, 2015 , ... ... a real-time eReferral system for diagnostic imaging in the Waterloo region. Using the ... and Nuclear Medicine tests directly from their electronic medical record (EMR) without the ...
(Date:11/26/2015)... ... November 26, 2015 , ... The Catalent Applied Drug Delivery ... to integrate dose form selection in early phase drug development. The first of ... and bringing together the UK’s emerging life sciences companies, corporate partners, and investors, ...
(Date:11/26/2015)... , ... November 26, 2015 , ... PRMA Plastic Surgery ... 19, 2015, our surgeons performed their 6,000th free flap breast reconstruction surgery! , “What ... up every day excited to rebuild lives and it’s an honor to have served ...
(Date:11/26/2015)... , ... November 26, 2015 , ... ... set of retro-fused, self-animating trailer titles with ProTrailer: Vintage. This newly styled ProTrailer ... classically-influenced trailer titles work with any font, giving users limitless opportunities to stylize ...
(Date:11/26/2015)... ... November 26, 2015 , ... Indosoft Inc., developer and distributor of ... server to improve system efficiency and reliability. , The new Q-Suite 6 platform is ... the system avoids locking itself into a specific piece of software for many key ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... , November 26, 2015 ... --> adds "Global Repaglinide ... "Investigation Report on China Repaglinide Market, ... forecasts data and information to its ... . --> ...
(Date:11/26/2015)... , Nov. 26, 2015 Research ... addition of the "2016 Future Horizons and ... (TDM) Market: Supplier Shares, Country Segment Forecasts, Competitive ... --> --> ... analysis of the Italian therapeutic drug monitoring market, ...
(Date:11/26/2015)... , November 26, 2015 /PRNewswire/ ... announced the addition of the  "2016 ... the European Cell Surface Marker Testing ... Opportunities"  report to their offering.  ... the addition of the  "2016 Future ...
Breaking Medicine Technology: