Navigation Links
Capturing cancer: A powerful new technique for early diagnosis
Date:7/14/2014

es were used in the training phase and the remaining 25 percent subjected to blind test.

Remarkably, an average diagnostic accuracy of over 98 percent was achieved, demonstrating the suitability of immunosignaturing for the simultaneous classification of multiple diseases.

Specifically, in one experimental trial, researchers were able to detect and distinguish a complex, heterogeneous diseasestage IV breast cancer, relative to 4 other cancers and healthy controls. In the second trial, 14 separate diseases were distinguished from one another as well as from healthy controls, through immunosignatures. Among the cancers tested were 3 different stages of breast cancer, 4 different brain cancers, 2 pancreatic diseases, ovarian cancer and 2 different blood cancers.

The study emphasizes the fact that incidence of cancer constitutes an unprecedented global challenge to healthcare infrastructure, particularly in the face aging populations. Early detection and treatment of cancer must be given highest priority in order to adequately address projected increases in cancer cases.

Immunoisignatures provide an attractive means of capturing disease complexity, offering a marked improvement in detection over traditional methods in which one-to-one molecular recognition events are measured and only one or a small number of analytes can be evaluated.

In addition to the problem of dilution of measurable analytes in conventional tests, the authors stress the considerable heterogeneity of cancer, which results in complexity at the molecular level that tends to evade characterization when only a few target analytes are evaluated.

The microarray chip used for the current study contains 10,000 imprinted peptides, of random sequence, which serve the role of artificial disease antigens used to poll the antibodies present in blood. The fact that the random sequence peptides are structurally unrelated to natural antigens allows the arr
'/>"/>

Contact: Joseph Caspermeyer
Joseph.Caspermeyer@asu.edu
Arizona State University
Source:Eurekalert  

Page: 1 2 3 4

Related medicine news :

1. Capturing circulating cancer cells could provide insights into how disease spreads
2. Capturing live tumor cells in the blood
3. Capturing a hard-wired variability
4. You Survived Cancer: Now Pay Attention to Your Overall Health
5. Veggies Like Broccoli, Cabbage May Help Fight Breast Cancer: Study
6. Surgery Rates Rising for Non-Melanoma Skin Cancer: Study
7. Many Young Adults at Risk of Skin Cancer: CDC
8. Common Painkillers May Help Prevent Skin Cancer: Study
9. New Drug Effective for Rare Genetic Skin Cancer: Studies
10. Multiple sclerosis patients have lower risk of cancer: UBC-VCH research
11. Prions and cancer: A story unfolding
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Capturing cancer: A powerful new technique for early diagnosis
(Date:8/28/2015)... ... August 28, 2015 , ... The ... consolidated as MDL 2545, Testosterone Replacement Therapy Products Liability Litigation, are in the ... of custodial files the PSC may receive for corporate employees involved in the ...
(Date:8/28/2015)... ... ... Yisrayl Hawkins, Pastor and Overseer at The House of Yahweh in Abilene, Texas, ... in order to ease the stress on the atmosphere, and lessen the number and ... the real cause of global warming and urges them to look into his studies ...
(Date:8/28/2015)... Knoxville, TN (PRWEB) , ... August 28, 2015 , ... ... surrounding the Centers for Medicare & Medicaid Services’ (CMS) proposal to mandate bundled ... 45-minute webinar , “Get Ready for Game Day: Comprehensive Care for Joint Replacement,” ...
(Date:8/28/2015)... , ... August 28, 2015 , ... Inc. magazine today ... list, an exclusive ranking of the nation’s fastest-growing private companies. The list was unveiled ... sales growth of 85% over the last three years, PREVENT ranks higher on the ...
(Date:8/28/2015)... ... ... launched their new website this summer. The new user-friendly site has a ... design. Website users will now have an improved browsing experience on their phones, tablets, ... the monthly turf-tips email, and find a local Super-Sod store all from the convenience ...
Breaking Medicine News(10 mins):Health News:National Testosterone Lawyers Provide Testosterone Lawsuit MDL Update 2Health News:National Testosterone Lawyers Provide Testosterone Lawsuit MDL Update 3Health News:National Testosterone Lawyers Provide Testosterone Lawsuit MDL Update 4Health News:Wake Up and Smell the Sick Atmosphere Says Yisrayl Hawkins in New Article This Week 2Health News:PYA Offers Complimentary CCJR Webina — Game On 2Health News:PYA Offers Complimentary CCJR Webina — Game On 3Health News:PREVENT Life Safety Ranks No. 3660 on the 2015 Inc. 5000 With Three-Year Sales Growth of 85% 2
... , , WASHINGTON , Jan. 27 ... the National Viral Hepatitis Roundtable (NVHR) issued the following ... Address.  NVHR is a coalition of more than 150 public, ... infection, morbidity, and mortality from chronic viral hepatitis that afflicts ...
... , 30 Groups Emphasize The Urgency Of ... Thousands of Americans , WASHINGTON , ... consumers, health professionals and providers recently sent a letter ... the exceptions process for Medicare Part B outpatient therapy ...
... from a team at the Providence Heart + Lung Institute ... (UBC) may lead to new treatment options for abdominal aortic ... no pharmacological treatments. An aortic aneurysm is a bulging ... If the aneurysm ruptures, it causes rapid blood loss and ...
... with end-stage kidney disease suffer physical, social, emotional and ... Hopkins Children,s Center shows that even mild to moderate ... life. The findings, reported in the February issue ... quality-of-life issues in children with chronic kidney disease is ...
... higher cost-sharing for outpatient visits may increase overall spending ... for doctor visits and other outpatient care reduces seniors, ... the unintended consequence of sharply increasing hospitalizations, a new ... inflating overall health-care spending and put vulnerable elderly at ...
... , ... breast cancer charity partners with the Vehicle Donation Processing Center to provide financial assistance ... ... (TBCS) has partnered with the Vehicle Donation Processing Center, Inc. to launch a vehicle ...
Cached Medicine News:Health News:NVHR Issues Challenge to Administration, Congress: Don't Leave 5 Million Americans Afflicted with Chronic Viral Hepatitis Out in the Cold with Budget Freeze 2Health News:NVHR Issues Challenge to Administration, Congress: Don't Leave 5 Million Americans Afflicted with Chronic Viral Hepatitis Out in the Cold with Budget Freeze 3Health News:Congress Urged to Take Immediate Action to Ensure Frail Patients Continue to Receive Critical Therapy Services 2Health News:Congress Urged to Take Immediate Action to Ensure Frail Patients Continue to Receive Critical Therapy Services 3Health News:Discovery points way for new treatment for aneurysms: UBC-Providence Research 2Health News:Even mild kidney disease harms a child's quality of life 2Health News:Raising Co-Pays for Doctor Visits Raises Seniors' Hospital Use 2Health News:Raising Co-Pays for Doctor Visits Raises Seniors' Hospital Use 3Health News: The Breast Cancer Society Launches Vehicle Donation Program 2Health News: The Breast Cancer Society Launches Vehicle Donation Program 3
(Date:8/27/2015)... 27, 2015  The Academy of Managed Care ... Administration,s (FDA,s) draft guidance and proposed rule that ... to bear a nonproprietary name with an FDA-designated ... a decision from the FDA on the naming ... stakeholders urging the agency to use the same ...
(Date:8/27/2015)... , Aug. 27, 2015  A recent ... KSSTA Knee Journal, compared the Arthrosurface HemiCAP® Wave ... design, versus an "onlay" design implant for isolated ... improvements in function and pain scores, none of ... of osteoarthritis (OA). However, 53% of the patients ...
(Date:8/27/2015)... CUPERTINO, Calif. , Aug. 27, 2015 ... management is scheduled to present at three upcoming healthcare ... , President and CEO, will present at the Rodman ... 10:00 a.m. Eastern time. The conference is being held ... York City . A live audio webcast of ...
Breaking Medicine Technology:AMCP Is Disappointed in FDA's Draft Guidance and Proposed Rule Calling for Suffix on Nonproprietary Names of Biological Products 2Study Demonstrates Dramatic Reduction in Progression of Osteoarthritis with the Arthrosurface "Inlay" Patellofemoral Implant Design Compared to Traditional "Onlay" Implant 2Study Demonstrates Dramatic Reduction in Progression of Osteoarthritis with the Arthrosurface "Inlay" Patellofemoral Implant Design Compared to Traditional "Onlay" Implant 3DURECT to Participate in Upcoming Healthcare Conferences 2
... ALR ), a global leader in enabling ... through the merger of rapid diagnostics and health management, ... JMP Securities Healthcare Conference being held September 27 through ... Avenue, New York.  Jon Russell, Vice President, Finance, will ...
... ALR ) announced today that, in connection with its ... it entered into a purchase agreement with the initial purchasers ... the offering was increased from $350.0 million to $400.0 million. ... offered at 100.0% of the aggregate principal amount of the ...
Cached Medicine Technology:Alere Inc. Announces Pricing of Senior Subordinated Notes Offering; Offering Size Increased to $400.0 Million 2
... Solution For Your Tracheostomy Care Needs, ... features the latest components for efficient and ... task. Designed by clinicians, these latex-free trays ... patient and caregiver. All of our trays ...
... Right Solution For Your Tracheostomy Care Needs, ... tray features the latest components for efficient ... control task. Designed by clinicians, these latex-free ... each patient and caregiver. All of our ...
... Kendall provides hospitals and alternate care ... tracheostomy care trays which offer the ... control. Designed with the guidance of ... trays provide exactly what is required ...
For use with cushioned neckband....
Medicine Products: