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Capsule endoscopy diagnoses more Crohn's disease recurrence after surgery than colonoscopy
Date:9/26/2007

said the studys lead author Vicente Pons Beltrn, MD, PhD, La Fe University Hospital. We believe this is due to capsule endoscopys ability to visualize the entire small intestine, including parts of the upper small intestine that colonoscopy is not designed to reach.

Capsule endoscopy allows physicians to examine the lining of the middle part of the gastrointestinal tract, which includes the three portions of the small intestine (duodenum, jejunum, ileum). A tiny camera is contained inside of a pill that the patient swallows. It captures images of the gastrointestinal tract as it travels through the body and transmits the images to a computer so the physician can view them and make a diagnosis.

Patients and Methods Recurrence after surgery to treat Crohns disease is frequent and unpredictable. The efficacy of post-surgery capsule endoscopy in detecting recurrence in patients with Crohn's disease is yet to be confirmed. The objective of this study was to assess the safety, accuracy, and therapeutic impact of capsule endoscopy. Twenty-four Crohns disease patients from La Fe University Hospital in Valencia, Spain who had ileocolonic resection, followed by reconnection of the ileum to the colon, were subjects in the study.

All patients were asymptomatic and not on any medical therapy for Crohns disease. Colonoscopy and capsule endoscopy were used to visualize and assess Crohn's disease at the anastomosis and in the remaining small intestine. Capsule endoscopy was performed within two weeks of colonoscopy. Investigators were blinded to the results of each technique. Patient comfort during the procedures was also recorded.

Results A colonoscopy was performed in all patients, although the end part of the small intestine could not be reached in three of them. Two of the patients had a narrowing in the small intestine, which precluded capsule endoscopy from being performed.

Recurrent Crohns disease was visualized in the rem
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Contact: Jennifer Michalek
jmichalek@asge.org
630-570-5632
American Society for Gastrointestinal Endoscopy
Source:Eurekalert

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