Navigation Links
Can't focus? Maybe it's the wrong time of month
Date:9/24/2010

Montreal September 24, 2010 Feeling a little sluggish and having trouble concentrating? Hormones might be to blame according to new research from Concordia University published in the journal Brain and Cognition. The study shows that high estrogen levels are associated with an inability to pay attention and learn the first such paper to report how this impediment can be due to a direct effect of the hormone on mature brain structures.

"Although estrogen is known to play a significant role in learning and memory, there has been no clear consensus on its effect," says senior author Wayne Brake, an associate professor at Concordia's Center for Studies in Behavioural Neurobiology. "Our findings, using a well-established model of learning called latent inhibition, shows conclusively that high estrogen levels inhibit the cognitive ability in female rodents."

Human females have high estrogen levels while they are ovulating. These high levels have also been shown to interfere with women's ability to pay attention.

"The similarity between human studies and our findings suggest that we have a good model for human learning," says first author Matthew Quinlan, a former Concordia doctoral student now a lecturer at California State University San Bernadino. "Rodent research is invaluable to us. We can tease out the real contributors and their respective roles in these systems. It is much more difficult to conduct comparable experiments in humans."

Latent inhibition: A model of learning

Latent inhibition is observed in many species and is believed to be the important part of learning, which enables individuals to interact successfully in their environment. It is a test of new memory formation.

In the Brake protocol, rats received a pre-exposure phase during which they were repeatedly exposed to a tone, with no consequence. Once they became used to this tone and ignored it, the test dynamics changed and another stimulus was linked to the tone. Rats with low levels of estrogen quickly learned that the tone was associated with the new stimulus whereas those with higher levels of estrogen took longer to form this memory.

"We only observed this effect in adult female rats," says Brake. "This and our other findings indicate that estrogen directly effects the brain, perhaps by interfering with brain signaling molecules. Our study helps clear up the controversy about the effects of estrogen, the next step is to look at how this occurs."


'/>"/>

Contact: Sylvain-Jacques Desjardins
s-j.desjardins@concordia.ca
51-484-824-245-068
Concordia University
Source:Eurekalert

Related medicine news :

1. Gum disease found to be significant public health concern
2. Non-invasive therapy significantly improves depression, UCLA researchers say
3. Significant advance announced in treatment of cervical cancer
4. Elevated heart rate over time linked to significant risk of death
5. Survey of coastal residents shows Gulf oil spill has significant impact on families
6. TCT 2010 to have significant impact on interventional cardiology practices and patient care
7. U of M study finds fast food chains have significantly decreased trans fats in cooking oils
8. Study shows universal surveillance for MRSA significantly decreased HAIs at PCMH
9. High-risk prostate cancer associated with significantly lower bone mineral content loss
10. FileHold Document Management Software Announces Significant Enhancements and Support for all New Microsoft Platforms
11. Bars, restaurants see no significant employment change under smoking bans in 2 cities
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/26/2017)... ... April 26, 2017 , ... Journal of Oral Implantology ... have severe consequences to overall dental health, including complications with speech, eating, and overcompensation ... dental implants to replace lost teeth. As the number of tooth replacements increase, it ...
(Date:4/26/2017)... ... April 26, 2017 , ... ... Hackensack, N.J. has been honored by Enterprising Women magazine as one of its ... world’s top women business owners. Winners have demonstrated that they have fast-growth businesses, ...
(Date:4/26/2017)... (PRWEB) , ... April 26, 2017 , ... RawTrition now ... easy way to get nutrients from SUPERFOODS! , RawTrition is taking nutrients ... the cellular level because the body recognizes its raw form (unlike the synthetically made ...
(Date:4/26/2017)... ... 26, 2017 , ... MYOLYN, a medical technology company dedicated ... received 510(k) clearance from the U.S. Food & Drug Administration (FDA) for two ... devices are stationary cycling systems that use MYOLYN’s patent-pending functional electrical stimulation ...
(Date:4/25/2017)... ... April 25, 2017 , ... ... Newport Beach, California, committed to raising awareness for Duchenne muscular dystrophy, and ... its randomized CAP-1002 (cardiosphere-derived cells) Phase I/II HOPE clinical trial in Duchenne ...
Breaking Medicine News(10 mins):
(Date:4/24/2017)... , April 24, 2017 Solentim, the ... announced the addition of a major new product ... Plate Seeding,). The VIPS has been developed for ... well microplates as part of the process to ... a simple and more reliable solution when compared ...
(Date:4/20/2017)... Research and Markets has announced the addition ... Addressing Production Complexities Through Risk Management and Quality by ... ... Market Prospects: Overcoming Production Complexities Through Risk Management and ... current trends in the global biosimilars market, with a ...
(Date:4/20/2017)... , April 20, 2017  AbbVie (NYSE: ... 99 percent (n=145/146) of chronic hepatitis C virus ... 5 or 6 and compensated cirrhosis (Child-Pugh A) ... (SVR 12 ) with its investigational, pan-genotypic regimen ... rates were seen following 12 weeks of G/P ...
Breaking Medicine Technology: