Navigation Links
Cancers of sweat glands, other skin-related structures may be increasing in United States
Date:6/21/2010

Cutaneous appendageal carcinomastumors of the skin appendages such as hair, nails, sweat glands and mammary glandsare rare but rates appear to be increasing in the United States, according to a report in the June issue of Archives of Dermatology, one of the JAMA/Archives journals.

"Cutaneous appendageal carcinomas are a rare and diverse group of complex neoplasms with diverse differentiation that frequently present a diagnostic challenge," the authors write as background information in the article. Because of their rarity, studies of these cancers have been limited.

Patrick W. Blake, B.S., of the National Cancer Institute, Bethesda, Md., and colleagues examined incidence rates, trends and survival rates of the disease using 16 cancer registries in the Surveillance, Epidemiology and End Results Program from 1978 to 2005. A total of 1,801 patients were identified for incidence analysis, 2,228 for trend analysis and 1,984 for survival analysis.

The age-adjusted incidence rates were 5.1 cases per 1 million people per year, with men more likely to develop one of the cancers than women. Hispanic whites, blacks and Asian/Pacific Islanders all had lower rates of incidence than non-Hispanic whites. The most common type was apocrine-eccrine carcinoma, or cancer of the sweat glands. Incidence rates increased with age, with a 100-fold difference between individuals age 20 to 29 years and those age 80 years and older.

Cutaneous appendageal carcinomas also became more common over time, with a 150-percent increase in incidence between 1978 to 1982 and 2002 to 2005. Rates of sweat gland cancers increased 170 percent and sebaceous carcinomas, cancers of glands in the eyelid, increased 217 percent. Overall, five-year survival rates were 99 percent for localized disease and 43 percent for disease that had spread to another part of the body.

"Cutaneous appendageal carcinoma incidence rates are increasing in the United States, especially for sebaceous carcinoma, perhaps related to improved recognition and classification, but factors such as UV exposure and immunosuppression may also play a role," the authors write. "Further increases in cutaneous appendageal carcinomas over time should prompt new strategies for cancer screening and early intervention of this cancer."


'/>"/>

Contact: NCI Press Officers
ncipressofficers@mail.nih.gov
301-496-6641
JAMA and Archives Journals
Source:Eurekalert

Related medicine news :

1. Coffee Might Guard Against Head, Neck Cancers
2. Study shows Hodgkin lymphoma survivors lack post-treatment screening for other cancers
3. Non-melanoma skin cancer may help identify survivors at increased risk for future cancers
4. ASCO data show serum DNA blood tests detect cancers with high sensitivity and specificity
5. Proton therapy carries precise, potent punch against childrens cancers
6. Targeted immunotherapy shows promise for metastatic breast, pancreatic cancers
7. Genes Link to Certain Cancers Questioned
8. Proton Therapy Carries Precise, Potent Punch Against Cancers for Patients at The Children's Hospital of Philadelphia
9. Drug in new class of targeted therapies shows early promise against blood-related cancers
10. U.S. Must Do More to Cut Cases of Environmental Cancers
11. Screening mammograms in younger women have low accuracy and detect few cancers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/5/2016)... ... February 05, 2016 , ... ... franchises from across the country gathered at the La Valencia Hotel in San ... PROSHRED Chicago was named the year’s most outstanding franchise, walking away with ...
(Date:2/5/2016)... York (PRWEB) , ... February 05, 2016 , ... Regular ... and find themselves having to wait longer to access the treadmills. It’s a predictable ... Year’s resolutions to lose weight and get in shape by joining gyms, starting new ...
(Date:2/5/2016)... (PRWEB) , ... February 05, 2016 , ... Boar’s Head ... just in time for this weekend’s Big Game. Take the stress out of your ... will keep your guests happy at every stage of the game. , “The key ...
(Date:2/5/2016)... ... February 05, 2016 , ... At its annual meeting held ... as Chairman of the National Board of Directors. Mr. McDermott succeeds former APDA Chairman, ... stated Leslie A. Chambers , APDA President and CEO. “Pat has tirelessly served ...
(Date:2/5/2016)... , ... February 05, 2016 , ... Stuart Bentkover, ... technology, the PicoSure. Designed to provide the most effective tattoo removal today, Dr. Bentkover ... unmatched results. , Developed by Cynosure, the PicoSure has been approved by the Food ...
Breaking Medicine News(10 mins):
(Date:2/5/2016)... , February 5, 2016 ... new market research report "Fetal (Labor & Delivery) and ... Antepartum), Warmer, Incubator, Pulse Oximeter, Phototherapy/Jaundice Management Devices, CPAP, ... by MarketsandMarkets, This report studies the global market over ... is estimated at USD 6.28 Billion in 2015 and ...
(Date:2/4/2016)... 2016 For hospitals considering enrollment in the ... in the program, the Health Resources and Services Administration,s ... , Mega-Guidance , could have significant impact on plans ... September 2016. Essential Insights , Daniel ... summarizes the Mega-Guidance,s key proposed changes, including a new ...
(Date:2/4/2016)... FOSTER CITY, Calif. , Feb. 4, 2016 ... (the "Company") today announced it has entered into ... and Exchange Commission (SEC) fully resolving the SEC,s ... Practices Act (FCPA).  Under the terms of the ... total of $12.8 million, including disgorgement, pre-judgment interest ...
Breaking Medicine Technology: