Navigation Links
Cancer therapies from the ocean?
Date:7/7/2008

Scientists from Aberdeen, Luxembourg and the South Pacific have studied the properties of natural products derived from animals found in Fijian waters, and shown that not only may certain compounds have potential use in anti-cancer therapies, but others may also be useful for improving drug delivery, currently one of the most significant problems faced by medical researchers. Professor Marcel Jaspars from the University of Aberdeen will present insights into these new compounds on Monday 7th July at the Society for Experimental Biology's Annual Meeting in Marseille [Session P2].

The team has focussed on finding compounds which interfere with a protein termed NF-kB. This particular protein is known to have a critical role in many types of cancer, as well as a number of other diseases including inflammatory bowel disease, arthritis and asthma, so there is a major drive to find molecules which can inhibit its activity. "We have tested a large number of marine species to see which can prevent NF-kB from working," explains Professor Jaspars. "A few animals, including sponges, soft corals and sea lilies, were examined further, and from these we have been able to isolate and characterise the compounds responsible. We have shown that one of these molecules is able to allow normal cell death (which NK-kB switches off in some cancerous cells) to start up again, a property which we will be going onto study in much more detail."

There is another possible application of molecules isolated from marine creatures that has the potential to have just as great an impact on the development of new medicines: "It is an unfortunate reality that currently, many new excellent drugs are discovered that cannot be delivered effectively to the places where they are required," Professor Jaspars reveals. "However, we have isolated one compound from a Mediterranean sponge that may help to end this trend. This molecule can reversibly create pores in cell membranes, a
'/>"/>

Contact: Holly Astley
hma25@cam.ac.uk
44-77928-55-259
Society for Experimental Biology
Source:Eurekalert

Page: 1 2

Related medicine news :

1. New ovarian stimulation technique offers more cancer patients the chance to preserve their fertility
2. Kidney Cancer Vaccine Shows No Boost in Survival
3. Susan G. Komen for the Cure(R)s Circle of Promise to Mobilize African American Women Against Breast Cancer at 2008 Music Festival
4. Circulating tumor cells can reveal genetic signature of dangerous lung cancers
5. Blood vessel inhibitor shows promise against metastatic thyroid cancer
6. New Drug Slows Thyroid Cancer
7. Circulating Tumor Cells Reveal Insights Into Lung Cancers
8. Smokeless Tobacco Products Do Raise Cancer Risk
9. DiagnoCures GCC marker for the staging of colorectal cancer discussed at the Eastern Cooperative Oncology Group
10. Designer diet for prostate cancer
11. Analysis of cancer incidence, mortality and survival combined reveals encouraging European trends
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/5/2015)... ... August 05, 2015 , ... HealthyYOU Vending says that recent Health ... the City & County of San Francisco are representative of initiatives across the county ... approved a measure from the City and County of San Francisco Board of Supervisors ...
(Date:8/5/2015)... ... August 05, 2015 , ... It is exciting ... of global organisations such as PhUSE or CDISC are currently bringing in the ... the Japanese PMDA and the European EMA. A move towards global harmonisation of ...
(Date:8/4/2015)... ... ... Fla. – After completing 2,400 hours in the Clinical Pastoral Education Programs at ... Dr. Barbara Thomas-Reddick to gain the skills and the know-how in the ... staff, and she was able to witness after leaving the patients’ bedside, how “ ...
(Date:8/4/2015)... ... ... NOVA Pride , Northern Virginia’s largest and newest LGBTQ nonprofit organization, invites ... them in paving “The Road Ahead” at the second annual Northern Virginia Pride Festival, ... from 12-9pm. In order to ensure the success of this important event, NOVA Pride ...
(Date:8/4/2015)... (PRWEB) , ... August 05, 2015 , ... The ... Pain and Obesity ”. , As corresponding author Professor Akiko Okifuji says “Both obesity ... often, although it is not to say that one causes the other. Rather, there ...
Breaking Medicine News(10 mins):Health News:HealthyYOU Vending says San Francisco’s ‘Soda Free Summer’ Initiative and Other Recent Health-related Ordinances Demonstrate Why Healthy Vending is a Growing Industry 2Health News:HealthyYOU Vending says San Francisco’s ‘Soda Free Summer’ Initiative and Other Recent Health-related Ordinances Demonstrate Why Healthy Vending is a Growing Industry 3Health News:Japan PMDA Publishes English Versions of Electronic Data Submission & Technical Conformance Guidance 2Health News:Japan PMDA Publishes English Versions of Electronic Data Submission & Technical Conformance Guidance 3Health News:New book shows how ‘The Presence of a Chaplain’ affects lives 2Health News:New book shows how ‘The Presence of a Chaplain’ affects lives 3Health News:NOVA Pride Announces Theme for the 2015 Northern Virginia Pride Festival 2Health News:NOVA Pride Announces Theme for the 2015 Northern Virginia Pride Festival 3Health News:NOVA Pride Announces Theme for the 2015 Northern Virginia Pride Festival 4Health News:The Association between Chronic Pain and Obesity published by Dove Medical Press 2
... -- For high-blood-pressure patients, preventing or reducing enlarged heart ... failure. The study is published in the Sept. 4 ... NewYork-Presbyterian Hospital/Weill Cornell Medical Center in New York City. ... or 12 million Americans, have LVH and are at ...
... Summaries of the,articles in the journal INQUIRY,s recently-released Vol. ... Savings in Part A and Part B? The Impact ... C.,Stuart, Becky A. Briesacher, Jalpa A. Doshi, Marian V. ... increases spending,on medications, this study finds no consistent evidence ...
... 13 "Profit, customers and,people are all linked together," ... Facing the Challenges of the 21st Century,Workforce. "If you ... people, your people,will take care of your customers, and ... the recent HR-focused conference of Best Practices, LLC,s Global,Benchmarking ...
... revolutionary unobtrusive sensor that collects and immediately transmits data ... in future. , Cufflink-sized and clipped behind the wearers ... First, it does not hinder performance, yet can gather ... step frequency, acceleration, response to shock waves travelling through ...
... Inverness Medical,Innovations, Inc. (Amex: IMA ), ... for the consumer and professional markets, announced,today the ... CTEC ). Inverness completed the acquisition through ... into Cholestech, after,Cholestech,s shareholders approved the deal at ...
... 12 AtriCure, Inc.,(Nasdaq: ATRC ), a medical ... surgical devices, announced,today that David J. Drachman, President and ... Partners 5th Annual Growth,Conference at the St. Regis Hotel ... a.m. PT. A live web cast and recording ...
Cached Medicine News:Health News:Preventing or reducing enlarged heart decreases risk of heart failure 2Health News:Medicare Prescription Drug Benefit, Nonprofit Hospitals, Ambulatory Surgery Centers, Statistical Methods, and Pay-For-Performance Highlighted In the Latest INQUIRY Journal 2Health News:Medicare Prescription Drug Benefit, Nonprofit Hospitals, Ambulatory Surgery Centers, Statistical Methods, and Pay-For-Performance Highlighted In the Latest INQUIRY Journal 3Health News:Broker a Suite of Research & Advisory Services to Enhance Human Resources 2Health News:Leading-edge body sensor could help produce sporting champions 2Health News:Inverness Completes Acquisition of Cholestech 2Health News:Inverness Completes Acquisition of Cholestech 3Health News:AtriCure to Present at ThinkEquity Partners 5th Annual Growth Conference 2
(Date:8/5/2015)... Aug. 5, 2015  Twist Bioscience, a ... that Emily Leproust, Ph.D., chief executive officer ... 2015 Wedbush PacGrow Healthcare Conference on Wednesday, August 12 ... Hotel in New York City. About ... our expertise is synthetic DNA. We have ...
(Date:8/5/2015)... EnteroMedics Inc. (NASDAQ: ETRM ), the ... obesity, metabolic diseases and other gastrointestinal disorders, today announced ... and Chief Executive Officer, is scheduled to present at ... on Thursday, August 13, 2015 at 11:30 pm Eastern ... Dr. Knudson will provide ...
(Date:8/5/2015)...  Butterfly Network was awarded today as one ... for 2015.  The company is democratizing medical imaging ... By integrating its novel imaging platform with deep ... virtuous cycle, learning as they image, and continually ... chosen by a professional jury among hundreds of ...
Breaking Medicine Technology:EnteroMedics to Present at the Canaccord Genuity 35th Annual Growth Conference 2EnteroMedics to Present at the Canaccord Genuity 35th Annual Growth Conference 3Butterfly Network Recognized as a Technology Pioneer by the World Economic Forum 2
... Dec. 10, 2010 NewCardio, Inc., (OTC Bulletin Board: ... today presented the results from a blinded drug safety ... to evaluate the performance of QTinno™ on its "testing" ... 11,672 electrocardiograms (ECGs) from the moxifloxacin and placebo arms ...
... BIOD ) today reported financial results for the fourth ... Fourth Quarter and Fiscal Year 2010 Financial Results Biodel ... of $8.1 million, or $0.31 per share, compared to a net ... ended September 30, 2009. Net loss applicable to ...
Cached Medicine Technology:NewCardio Presents Results for Cardiac Safety Research Consortium Blinded Drug Safety Study 2NewCardio Presents Results for Cardiac Safety Research Consortium Blinded Drug Safety Study 3NewCardio Presents Results for Cardiac Safety Research Consortium Blinded Drug Safety Study 4NewCardio Presents Results for Cardiac Safety Research Consortium Blinded Drug Safety Study 5NewCardio Presents Results for Cardiac Safety Research Consortium Blinded Drug Safety Study 6Biodel Reports Fourth Quarter and Fiscal Year 2010 Financial Results 2Biodel Reports Fourth Quarter and Fiscal Year 2010 Financial Results 3Biodel Reports Fourth Quarter and Fiscal Year 2010 Financial Results 4Biodel Reports Fourth Quarter and Fiscal Year 2010 Financial Results 5Biodel Reports Fourth Quarter and Fiscal Year 2010 Financial Results 6Biodel Reports Fourth Quarter and Fiscal Year 2010 Financial Results 7
Sierra Wave Quickreport eliminates most dictation. Study driven functions make testing faster and easier. Complete 2/4 channel EMG/NCV/EP....
...
Trial lens set +/- Cyl....
... engineering and innovative design, the Burton 7500-I ... masterful workmanship. At Burton, we set out ... a truly innovative concept, but to set ... quality construction and stringent testing, we devote ...
Medicine Products: