Navigation Links
Cancer theory stands the test of time -- rediscovering Boveri a century later
Date:2/29/2008

COLD SPRING HARBOR, N.Y. Rarely has a book in the biological sciences proved as prescient as Theodor Boveris 1914 monograph Concerning the Origin of Malignant Tumours. Out of print for decades and previously almost impossible to track down, the book is now available as a new and authoritative translation, co-published by Cold Spring Harbor Laboratory Press and The Company of Biologists.

Concerning the Origin of Malignant Tumours had a huge impact on cancer research. In it, Boveri was the first to argue that cancer is caused by defects in chromosomes and that these can be caused by a failure of cells to divide properly. He also proposed that the cells natural urge is to divide and that it is held in check by specific mechanisms that prevent cancer almost a hundred years later we know this to be true, having identified so-called tumor suppressors like the retinoblastoma protein. Perhaps most astonishingly, Boveri also predicted the existence of genes, suggesting that hereditary characters are aligned along chromosomes in a specific order.

Regularly quoted and frequently misquoted the only English version of Concerning the Origin of Malignant Tumours ever available before was a rare translation by Boveris wife, who was not a biologist. The new translation is by Sir Henry Harris, Regius Professor of Medicine at Oxford University, and includes extensive annotations in which Harris discusses the relevance of Boveris views today.

Reviewing the book, leading geneticist Felix Mitelman wrote that he cannot find superlatives enough to praise the lucid text, adding that the annotations contain words of wisdom that I wish could be made compulsory reading.


'/>"/>

Contact: Ingrid Benirschke
benirsch@cshl.edu
619-275-6021
Cold Spring Harbor Laboratory
Source:Eurekalert  

Page: 1

Related medicine news :

1. When couples face the diagnosis of cancer, women carry a larger emotional burden than men
2. Vitamin E Supplements May Raise Lung Cancer Risk
3. Certain vitamin supplements may increase lung cancer risk, especially in smokers
4. New study of targeted therapies for breast cancer -- model for global clinical trials
5. Broccoli Sprout Extract Hinders Bladder Cancer Development
6. Heart Hormones Beat Back Cancers in Mice
7. Cancer-related protein may play key role in Alzheimers disease
8. Weill Cornell team identifies potential new drug targets against hormone-dependent breast cancer
9. Atypical protein kinase C stabilizes SRC-3 levels in breast cancer cells
10. Breast cancer death rates among black women not decreasing across all states
11. Scientists Find Cancer Culprits in Cigarette Smoke
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Cancer theory stands the test of time -- rediscovering Boveri a century later
(Date:10/13/2017)... Calif. (PRWEB) , ... October 13, 2017 , ... Many ... dementia. However, many long-term care insurance companies have a waiver for care if the ... 90-day elimination period, when the family pays for care, is often waived, so the ...
(Date:10/13/2017)... ... , ... Global Healthcare Management’s 4th Annual Kids Fun Run brought out many ... event, sponsored by Global Healthcare Management’s CEO, Jon Letko, is aimed at getting kids ... of all ages; it is a non-competitive, non-timed event, which is all about having ...
(Date:10/13/2017)... ... October 13, 2017 , ... Coveros, a ... has been awarded a contract by the Center for Medicare and Medicaid Services ... accelerate the enterprise use of Agile methodologies in a consistent and high value ...
(Date:10/12/2017)... , ... October 12, 2017 , ... ... services for healthcare compliance program management, will showcase a range of technology and ... for Assisted Living (NCAL) Convention and Expo to be held October 14–18, 2017 ...
(Date:10/12/2017)... Wis. (PRWEB) , ... October 12, 2017 , ... ... standard products to meet the demand of today’s consumer and regulatory authorities worldwide. ... of probiotic experts and tested to meet the highest standard. , These ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... ORANGE COUNTY, Calif. , Oct. 10, 2017  NDS received ... Mobile  — a medical-grade battery-powered display stand specifically designed for ... aims to transform technology into a clinical solution to support the ... costs. Innovative Design ... NDS ZeroWire Mobile Wireless Solution ...
(Date:10/4/2017)... to the Centers for Disease Control and Prevention (CDC), influenza vaccination ... is helping communities across Massachusetts , Connecticut ... flu shots through the end of the month. *Some exclusions ... ... shot is by the end of October, according to the Centers for ...
(Date:10/2/2017)... , Oct. 2, 2017 Halo Labs announces the European ... system called the HORIZON at MIBio 2017 in Cambridge, ... and visible particulate matter in biopharmaceutical samples with unprecedented speed and ... the novel technique Backgrounded Membrane Imaging. ... The HORIZON subvisible particle analysis system ...
Breaking Medicine Technology: