Navigation Links
Cancer theory stands the test of time -- rediscovering Boveri a century later

COLD SPRING HARBOR, N.Y. Rarely has a book in the biological sciences proved as prescient as Theodor Boveris 1914 monograph Concerning the Origin of Malignant Tumours. Out of print for decades and previously almost impossible to track down, the book is now available as a new and authoritative translation, co-published by Cold Spring Harbor Laboratory Press and The Company of Biologists.

Concerning the Origin of Malignant Tumours had a huge impact on cancer research. In it, Boveri was the first to argue that cancer is caused by defects in chromosomes and that these can be caused by a failure of cells to divide properly. He also proposed that the cells natural urge is to divide and that it is held in check by specific mechanisms that prevent cancer almost a hundred years later we know this to be true, having identified so-called tumor suppressors like the retinoblastoma protein. Perhaps most astonishingly, Boveri also predicted the existence of genes, suggesting that hereditary characters are aligned along chromosomes in a specific order.

Regularly quoted and frequently misquoted the only English version of Concerning the Origin of Malignant Tumours ever available before was a rare translation by Boveris wife, who was not a biologist. The new translation is by Sir Henry Harris, Regius Professor of Medicine at Oxford University, and includes extensive annotations in which Harris discusses the relevance of Boveris views today.

Reviewing the book, leading geneticist Felix Mitelman wrote that he cannot find superlatives enough to praise the lucid text, adding that the annotations contain words of wisdom that I wish could be made compulsory reading.


Contact: Ingrid Benirschke
Cold Spring Harbor Laboratory

Page: 1

Related medicine news :

1. When couples face the diagnosis of cancer, women carry a larger emotional burden than men
2. Vitamin E Supplements May Raise Lung Cancer Risk
3. Certain vitamin supplements may increase lung cancer risk, especially in smokers
4. New study of targeted therapies for breast cancer -- model for global clinical trials
5. Broccoli Sprout Extract Hinders Bladder Cancer Development
6. Heart Hormones Beat Back Cancers in Mice
7. Cancer-related protein may play key role in Alzheimers disease
8. Weill Cornell team identifies potential new drug targets against hormone-dependent breast cancer
9. Atypical protein kinase C stabilizes SRC-3 levels in breast cancer cells
10. Breast cancer death rates among black women not decreasing across all states
11. Scientists Find Cancer Culprits in Cigarette Smoke
Post Your Comments:
Related Image:
Cancer theory stands the test of time -- rediscovering Boveri a century later
(Date:6/24/2016)... CA (PRWEB) , ... June 24, 2016 , ... A ... procedures that most people are unfamiliar with. The article goes on to state that ... but also many of these less common operations such as calf and cheek reduction. ...
(Date:6/24/2016)... ... June 24, 2016 , ... June 19, 2016 is ... associated with chronic pain and the benefits of holistic treatments, Serenity Recovery Center ... suffering with Sickle Cell Disease. , Sickle Cell Disease (SCD) is a disorder of ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... Sessions in Dallas that it will receive two significant new grants to support ... as PHA marked its 25th anniversary by recognizing patients, medical professionals and scientists ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... for accelerated orthodontic treatment. Dr. Cheng has extensive experience with all areas of ... AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct to ...
(Date:6/24/2016)... ... June 24, 2016 , ... Topical BioMedics, Inc, makers of Topricin and MyPainAway Pain Relief Products, ... minimum wage raise to $12 an hour by 2020 and then adjusting it yearly to ... value of the minimum wage, assure the wage floor does not erode again, and make ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... DUBLIN , June 23, 2016 ... the "Pharmaceutical Excipients Market by Type (Organic Chemical ... Preservative), Formulation (Oral, Topical, Coating, Parenteral) - Global Forecast ... The global pharmaceutical excipients ... 2021 at a CAGR of 6.1% in the forecast ...
(Date:6/23/2016)... Research and Markets has announced the addition of the ... to 2022" report to their offering. ... financial data derived from varied research sources to present unique ... on the market during the next five years, including a ... markets, regional and country level analysis. The report provides a ...
(Date:6/23/2016)... June 23, 2016 Bracket , a leading ... next generation clinical outcomes platform, Bracket eCOA (SM) 6.0, ... June 26 – 30, 2016 in Philadelphia ... Clinical Outcome Assessment product of its kind to fully integrate ... Bracket eCOA 6.0 is a flexible platform for electronic ...
Breaking Medicine Technology: