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Cancer targeted treatments from space station discoveries
Date:2/27/2014

s already begun. The space station research led to 13 licensed microcapsule-related patents and two that are pending. In addition, NuVue has designed devices integrating the delivery of the MEPS-II microcapsules with enhanced ultrasound visualization and cryotherapeutic effects, which are the subject of four additional issued and three pending patents.

NuVue also is currently seeking FDA approval of MEPS microcapsules containing pharmaceuticals and marker imaging agents to view MEPS microcapsules during ultrasound. Fortunately, the MEPS microcapsules were made in NASA labs for the space station under stringent conditions comparable to those of existing FDA requirements.

Through the use of NuVue's specialized biopsy needles working in concert with their enhanced ultrasound guided visualization technology, the needles are visible by an ultrasound imaging system. This allows for a targeted and site-specific approach of the MEPS microencapsulated drug delivery to the tumor. With this targeted approach, the MEPS microcapsules reduce the amount of unpleasant side effects of chemotherapy, whereas normal chemotherapy involves pharmaceutical injection into the entire body to treat cancer cells present in a patient. The microcapsules can also include a combination of drugs tailored to a specific patient, and they can be engineered for time release, providing longer-lasting therapeutic effects within the patient's cancerous tissues.

"Overall, this amounts to a combination of unique things that individually work, but put together work much better," said Morrison. "Microcapsules are a device that can be used together with ultrasound needles to mark the biopsy site for diagnosis. They can also mark the perimeter and margin of the tumor. When properly implemented, ultrasound can monitor the progress of any tumor therapy with the new MEPS marker imaging microcapsules being positioned within the tumor tissues, even if the therapeutic delivered was not th
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Contact: Laura Niles
Laura.E.Niles@nasa.gov
281-244-7069
NASA/Johnson Space Center
Source:Eurekalert  

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