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Cancer researchers seek safe reduction of radiotherapy
Date:10/2/2007

ester team are using samples from VORTEX to carry out VORTEX-BIOBANK, a study that aims to develop a tumour profile that will identify patients with an increased likelihood of secondary cancer. The team also aims to investigate associations between common genetic variation and a patient's risk of radiation induced side-effects in this particular cancer, as they are doing for a variety of other cancers in RAPPER.

Miss Rebecca Elliott, who will make a presentation about the team's work at the conference today, says: "There is exciting high-throughput technology out there and we are looking at the possibility of individualising patient treatment. The technology allows us to look at the variation and expression of genes to see which genes indicate who will be sensitive to radiotherapy. In future we will have a patient profile - if you have certain versions of genes x, y and z, then you have the chance of getting toxicity one hundred times more than someone with other versions."

"Although we are still collecting samples and are some way off getting our final results, it is an important new pathway in cancer research."


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Contact: Mikaela Sitford
Mikaela.Sitford@manchester.ac.uk
07-768-980-942
University of Manchester
Source:Eurekalert

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