Navigation Links
Cancer researchers receive NIH grant to advance brain tumor therapies from lab to clinical trials
Date:4/24/2008

Cancer researchers at Childrens Hospital of Pittsburgh of UPMC and the University of Pittsburgh Cancer Institute (UPCI) will further develop novel treatments for brain tumors through a new, five-year, $6.24 million grant to the University of Pittsburgh School of Medicine.

The grant from the National Institute of Neurological Disorders and Stroke (NINDS) will fund three projects aimed at developing cutting-edge treatment strategies for a type of brain tumor known as gliomas. The projects are led by principal investigator Ian Pollack, MD, chief of the Division of Pediatric Neurosurgery at Childrens Hospital and director of the UPCI Brain Tumor Program. This is the second five-year grant the Brain Tumor Program project has received from the NINDS.

In the laboratory over the last five years, our researchers have developed three unique and promising approaches to treating gliomas, which are the most common form of brain tumors, Dr. Pollack said. Over the next five years, our goal is to take these approaches from the laboratory to clinical trial and begin to have a direct impact on patients diagnosed with brain tumors.

The three projects and their respective investigators are:

  • Molecularly targeted therapies that interrupt the signaling pathways in the brain that drive tumor growth Dr. Pollack, also the Walter Dandy Professor of Neurosurgery at the University of Pittsburgh School of Medicine

  • Immunotherapy using segments of proteins that are overexpressed by brain tumors to vaccinate patients against tumor growth Hideho Okada, MD, PhD, associate professor in the departments of Neurological Surgery and Surgery at the University of Pittsburgh School of Medicine

  • Viral vectors (a modified herpes virus) to kill tumor cells while leaving other cells intact Joseph C. Glorioso III, PhD, chair of the Department of Microbiology and Molecular Genetics at the University of Pittsburgh Scho
    '/>"/>

Contact: Marc Lukasiak
marc.lukasiak@chp.edu
412-692-7919
Children's Hospital of Pittsburgh
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Conventional prognostic factors fail to explain better prostate cancer survival in most Asian men
2. Survival differences by race most apparent in advanced stages of breast cancer
3. MRI finds breast cancer before it becomes dangerous
4. Investigators uncover intriguing clues to why persistent acid reflux sometimes turns into cancer
5. Pathway links inflammation, angiogenesis and breast cancer
6. Radiologists encouraged to look beyond cancer for clinically unseen diseases
7. Diet high in meat, fat and refined grains linked to risk for colon cancer recurrence, death
8. Immune deficiency linked to a type of eye cancer
9. Drop in breast cancer incidence linked to hormone use, not mammograms
10. Breast cancer prevention practices vary across Canada
11. First biomarker discovered that predicts prostate cancer outcome
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/28/2015)... 28, 2015 Pitching speed, player’s height, and ... shoulder and elbow injuries, according to new research released today ... ) Specialty Day. , “Our findings indicate that a 10 ... in likelihood of a history of injury, a 10 mile ... increase likelihood of a history of injury, and playing for ...
(Date:3/28/2015)... (PRWEB) March 28, 2015 Delaying rotator ... be necessary, according to research presented today at the ... Specialty Day. , “Our study compared results for 170 ... underwent an additional glenohumeral joint capsule release procedure to ... Murrell MD, PhD, lead author from St. George Hospital ...
(Date:3/28/2015)... (PRWEB) March 28, 2015 Andrew Hawley of ... 1960's Who psychedelic concert posters. The Who and the Doors ... on August 2, 1968. According to Hawley, “The Who toured ... concert halls and college campuses. Perhaps the most famous Who ... Jim Morrison and the Doors on August 2, 1968 at ...
(Date:3/28/2015)... La Mirada, CA (PRWEB) March 28, 2015 ... with ear, nose and throat disorders, are ... Tinnitus is a common issue which is characterized by ... ears. Affecting 1 in 5 people, tinnitus is a ... or disorder and while it is non-fatal, tinnitus can ...
(Date:3/28/2015)... March 28, 2015 ARDX will sponsor the ... 12pm -3pm at the Chesapeake Conference Center in Chesapeake, Virginia. ... an empowering event for women in the Hampton Roads region. ... Stories of Women’s Lives. Women grow stronger through sharing ... other. This year the WWC™ theme is T-talk where ...
Breaking Medicine News(10 mins):Health News:Researchers Highlight Shoulder and Elbow Injury Possibility in Youth Players 2Health News:No Need to Delay Rotator Cuff Surgery, Study Shows 2Health News:Avid Collector from Vintage Rock Posters, Inc. Announces His Search For Original 1960's Who Psychedelic Concert Posters. 2Health News:Healthpointe now Offering Tinnitus Treatments in Clinics throughout Southern California 2
... Union asks board member to seek restatement of Beth ... Staples director Martin Trust,should apply the same Sarbanes-Oxley standards ... role on the board of Beth Israel Deaconess,Medical Center ... East. Trust is the CEO of Samtex and a ...
... Advisory Board Company,(Nasdaq: ABCO ) announced today ... Michael T. Kirshbaum, Chief Financial Officer and Robert,Musslewhite, ... upcoming investor conferences., Mr. Williams will present ... at,the UBS 18th Annual Global Healthcare Services Conference, ...
... in Long-Term Care: A Board of Directors Dashboard, ... Office of Inspector General (OIG) for the Department of ... Association (HCCA),present the challenges and opportunities for the boards ... of Care Dashboard." A,Quality of Care Dashboard is a ...
... Fla., Feb. 6 Mangrove Employer Services, a,leading ... Payroll, Benefits Administration and Self Service solutions,announces the ... Mangrove Employer Services teamed up with an ... in electronic benefits,payment services, in 2007 to provide ...
... NAPA, Calif., Feb. 6 Senetek PLC (OTC,Bulletin ... the development,of technologies that target the science of ... on Pyratine-6(TM) at the 66th Annual Meeting,of the ... In his presentation to the Academy, Dr. ...
... after , , WEDNESDAY, Feb. 6 (HealthDay News) -- An advanced ... harbingers of Alzheimer,s disease, can develop in just 24 hours. ... Hyman, leader of the group reporting the finding in the ... develop, damage is evident in nearby nerve cells almost immediately, ...
Cached Medicine News:Health News:Staples Board Member Should Use Sarbanes-Oxley Disclosure Rules in Non-Profit Role, Asserts 1199 SEIU 2Health News:The Advisory Board Company to Present at Upcoming Conferences 2Health News:OIG and HCCA Issue Government-Industry Roundtable Report 2Health News:Mangrove Announces Health Savings Account (HSA) and Health Reimbursement Account (HRA) Product Launches 2Health News:Dr. Neil Sadick Presents on Pyratine-6(TM) at the Annual Meeting of the American Academy of Dermatology 2Health News:Alzheimer's Plaques Can Form in One Day 2
(Date:3/27/2015)... 27, 2015 Concord Medical Services Holdings ... CCM ), a leading specialty hospital management solution ... radiotherapy and diagnostic imaging centers in ... a purchase agreement under which Concord Medical Services ... the Company, agreed to acquire the Fortis Surgical ...
(Date:3/26/2015)... , March 26, 2015  The Burzynski Research ... study independently conducted by the Department of Surgery ... Japan have been published. The study, ... hepatic arterial infusion as post-operative adjuvant therapy with ... of the liver. A total ...
(Date:3/26/2015)... March 26, 2015 Huntington Memorial Hospital is ... perform transcatheter aortic valve replacement (TAVR), a minimally invasive ... revolutionary new way to replace an aortic valve without ... lung machine. The procedure is performed by ... Azhil ( Alex) Durairaj , MD, interventional cardiologist and ...
Breaking Medicine Technology:Concord Medical Announces Acquisition of Fortis Surgical Hospital in Singapore 2Concord Medical Announces Acquisition of Fortis Surgical Hospital in Singapore 3Huntington Memorial Hospital Performs Groundbreaking Minimally Invasive Replacement of Heart Valves 2
... Mylan Inc. (Nasdaq: MYL ) today ... approval from the U.S. Food and Drug Administration (FDA) ... Acid Injection, 100 mg/mL, packaged in 1,000 mg/10 mL ... Pharmacia & Upjohn,s Cyklokapron® Injection, which is indicated for ...
... Dec. 1, 2011 /PRNewswire-iReach/ -- Global ... Pipeline Analysis, Competitive Landscape and Market Forecasts to ... (Photo:   http://photos.prnewswire.com/prnh/20111201/CG15956 ) ... deliver insulin in a precisely controlled manner at ...
Cached Medicine Technology:GiiResearch.com: Insulin Pumps - Availability of Reimbursement and Favorable Clinical Trial Data to Drive Market Growth 2GiiResearch.com: Insulin Pumps - Availability of Reimbursement and Favorable Clinical Trial Data to Drive Market Growth 3
...
Knot tier...
... The Blitz Suture Retriever is for arthroscopic and ... of design eliminates complicated procedural steps. It ... of suture material and in conjunction with,anchors or ... A small, curved needle tip permits the placement ...
... Blitz Suture Retriever is for arthroscopic and open ... design eliminates complicated procedural steps. It may ... suture material and in conjunction with,anchors or screws ... small, curved needle tip permits the placement of ...
Medicine Products: