Navigation Links
Cancer researchers discover new type of retinoblastoma in babies
Date:3/12/2013

(TORONTO, Canada March 13, 2013) A team of Canadian and international cancer researchers led by Dr. Brenda Gallie at the Princess Margaret Cancer Centre, University Health Network (UHN), has discovered a new type of retinoblastoma, a rapidly developing eye cancer that affects very young babies a finding that can immediately change clinical practice and optimize care for these children.

The finding, published online today in Lancet Oncology, is a breakthrough in recognizing that a single cancer gene (an oncogene) drives an aggressive retinoblastoma that starts long before birth in families with no history of the disease, says surgeon Dr. Gallie, an ophthalmologist who is also affiliated with The Hospital for Sick Children (SickKids) and a Professor in the Faculty of Medicine, University of Toronto.

"This research completely challenges conventional thinking and clinical practice," says Dr. Gallie. "The common type of retinoblastoma is initiated by damage to both copies of the RB1 tumor suppressor gene; the predisposition to this type of retinoblastoma can be inherited, so the other eye of the child and those of infant relatives are at risk to develop tumours. When we remove the eye with a large tumour in very young babies and show it is the new oncogene-driven type of retinoblastoma, there is believed to be zero risk for retinoblastoma developing in the other eye or in other infants in the family. This is a major advance in personalized cancer medicine for these children and families."

The oncogene-driven tumours are much larger than those anticipated in children with inherited retinoblastoma at the same age. "The earliest diagnosis comes when parents observe a white (instead of black) pupil of the eye, and the doctors listen to their observations and understand the urgency of referral. Sometimes Mom really does know best and clinicians should pay close attention."

Although less than 2% of unilateral retinoblastoma tu
'/>"/>

Contact: Jane Finlayson
jane.finlayson@uhn.ca
416-946-2846
University Health Network
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Many Ovarian Cancer Patients Denied By-the-Book Care, Study Says
2. Medicare Spending Not Linked to Longer Cancer Survival
3. Bitter melon juice prevents pancreatic cancer in mouse models
4. Penn study: Financial incentives affect prostate cancer treatment patterns
5. Repairing the nose after skin cancer in just one step
6. Lung Cancer Asbestos Victims Center Now Urges Families Of A Lung Cancer Victim To Ask If The Victims Was Exposed To Asbestos At Work And To Call them-If The Answer Is Yes
7. Dr. Gary McClain of JustGotDiagnosed.com Addresses Breast Cancer Support Group
8. Regenstrief and IU study investigates older adults views on cancer screening
9. Daily Aspirin Linked to Lower Risk for Deadly Skin Cancer in Women
10. Trio of biomarkers may help identify kidney cancer in early stages
11. Abdominal Chemo Bath May Extend Survival in Ovarian Cancer Patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/19/2014)... 2014 For decades it has been ... chiropractic adjustments are dangerous and cause strokes, cervical artery ... they do not recommend chiropractic to their patients. Now ... do refer to chiropractors because they have read the ... new research has popped up that tries to cast ...
(Date:8/19/2014)... week,s JAMA highlights the importance of physicians ... to treat patients. Written by Robert Vinci, MD, chief ... pediatrics at Boston University School of Medicine and Howard ... examines results of a study published in the same ... doctors can often over-emphasize certain types of data. , ...
(Date:8/19/2014)... Recently, UWDress.com, a professional company of women’s dresses and related ... formal evening dresses . Additionally, the firm has launched a ... moment, all of them can be ordered at discounted rates, ... until August 27, 2014. , The company puts much ... that women of all shapes can be graceful and charming. ...
(Date:8/19/2014)... NJ (PRWEB) August 19, 2014 Horizon Blue ... TOUR pro Morgan Hoffmann are once again teaming up ... a charitable cause through a Walking Challenge, and Horizon BCBSNJ ... well through a course challenge of their own. , Horizon ... that it is making a $5,000 donation to the New ...
(Date:8/19/2014)... August 19, 2014 Drews Dental Services is ... D.D.S., to vice president of the Maine Dental Association (MDA). ... three years, Dr. Drews has now been sworn in to ... serving his term as vice president and being a part ... as the First District Caucus in 2015. He plans to ...
Breaking Medicine News(10 mins):Health News:Is It True That the Chiropractor Can Cause a Stroke? Dr. Harbison of AlignLife Wood River Speaks Up 2Health News:Is It True That the Chiropractor Can Cause a Stroke? Dr. Harbison of AlignLife Wood River Speaks Up 3Health News:Is It True That the Chiropractor Can Cause a Stroke? Dr. Harbison of AlignLife Wood River Speaks Up 4Health News:Review of clinical treatment of bronchiolitis in infants reveals over-reliance on one test 2Health News:Cheap Plus Size Formal Evening Dresses Announced By UWDress.com 2Health News:Horizon Blue Cross Blue Shield of New Jersey Pairs up with PGA TOUR Pro Morgan Hoffmann for Walking Challenge During The Barclays for Charity and to Promote Good Health 2Health News:Horizon Blue Cross Blue Shield of New Jersey Pairs up with PGA TOUR Pro Morgan Hoffmann for Walking Challenge During The Barclays for Charity and to Promote Good Health 3Health News:Horizon Blue Cross Blue Shield of New Jersey Pairs up with PGA TOUR Pro Morgan Hoffmann for Walking Challenge During The Barclays for Charity and to Promote Good Health 4Health News:Dr. Drews Elected VP of Maine Dental Association 2
... SAN JUAN, Puerto Rico, Nov. 30 How exposed are ... damaging effects? Do you remember the,date of your next eye ... Find the answers to these questions and more,information about eye ... . , Over 56 ...
... Medical Inc., a leading manufacturer of breast MRI coils ... announcing an OEM Distribution Agreement for Sentinelle,s Vanguard(R) T-Series ... (RSNA) annual meeting in Chicago, Nov. 30 - Dec. ... Under this agreement, Toshiba will offer the Sentinelle ...
... the arteries , , SUNDAY, Nov. 30 (HealthDay News) -- The ... summer,s spike in gas prices may be a boon to ... long list of risk factors for heart disease and stroke. ... data that links particulate air pollution with cardiovascular disease and ...
... FUJIFILM Medical Systems USA is,pleased to announce the ... 100 percent of the Empiric stock, making the vendor ... step,in Fujifilm,s growth strategy, and a demonstration of the ... health information technology. , ...
... Summit: From Vision to Action, is set for December 1-2, ... together more than 300,stakeholders in public health in Colorado from ... "The work at this summit will be of ... delivery of basic health services," said Chris,Wiant, Caring for Colorado ...
... Banderas launched his fifth,fragrance, BLUE SEDUCTION FOR WOMEN, earlier ... cast members from Tony Award(R) Winning Best Musical, "In,the ... Roses, Ballet,Hispanico School of Dance, R. Evolucion Latina, Steps ... (See video from PUIG USA at:, http://media.medialink.com/WebNR.aspx?story=36005 ...
Cached Medicine News:Health News:Prevention and Eyecare Begin at Home 2Health News:Sentinelle Medical Enters OEM Distribution Agreement with Toshiba 2Health News:Heavy Traffic Can Be Heartbreaking 2Health News:Heavy Traffic Can Be Heartbreaking 3Health News:Fujifilm Acquires Information Systems Vendor Empiric 2Health News:Fujifilm Acquires Information Systems Vendor Empiric 3Health News:Hundreds to Gather for Colorado Public Health Summit 2
(Date:8/19/2014)... , Aug. 19, 2014  Stryker Corporation,s Orthopaedics Division, ... Champions Tour, is bringing its message of joint health to ... Jersey this week at The Barclays.  The company,s ... in the Spectator Village near the 17 th fairway ... starting on Thursday, August 21 st .    ...
(Date:8/19/2014)... 19, 2014  Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) will ... , Sanofi and Regeneron will host an IR Thematic Conference Call ... September 2, 2014 , Baird 2014 Healthcare Conference ... 2014 , Citi,s 9 th Annual Biotech ... 4, 2014 , Morgan Stanley Global Healthcare Conference ...
(Date:8/19/2014)... ENGLEWOOD, Colo. , Aug. 19, 2014 /PRNewswire/ ... of Ampio Pharmaceuticals, Inc. (NYSE MKT: ... 73 rd Annual Meeting of the American ... of Acute Care Surgery in Philadelphia, ... 10-13, 2014.  The presentation will report results from ...
Breaking Medicine Technology:Stryker, The Official Joint Replacement Products Of The PGA TOUR, Welcomes Golf Fans To Its Home State Of New Jersey For The Barclays 2Stryker, The Official Joint Replacement Products Of The PGA TOUR, Welcomes Golf Fans To Its Home State Of New Jersey For The Barclays 3Stryker, The Official Joint Replacement Products Of The PGA TOUR, Welcomes Golf Fans To Its Home State Of New Jersey For The Barclays 4Stryker, The Official Joint Replacement Products Of The PGA TOUR, Welcomes Golf Fans To Its Home State Of New Jersey For The Barclays 5Luoxis Announces Presentation of Positive Clinical Findings from Five-Year Clinical Study of Traumatic Brain Injury and Oxidation-Reduction Potential at 2014 American Academy of Surgical Trauma Meeting 2Luoxis Announces Presentation of Positive Clinical Findings from Five-Year Clinical Study of Traumatic Brain Injury and Oxidation-Reduction Potential at 2014 American Academy of Surgical Trauma Meeting 3
... Nov. 16, 2011 Hotspur Technologies today announced ... Catheter in the United States and select international ... Hotspur,s innovative GPSCath™ Balloon Dilatation Catheter integrates ... physicians to inject contrast during a procedure without ...
... DIEGO, Nov. 16, 2011 OncoSec Medical Incorporated (OTCBB: ... to treat solid tumor cancers, today announced it has ... to analyze subjects in three OncoSec Phase II ... cutaneous T-cell lymphoma with the goal of identifying biomarkers ...
Cached Medicine Technology:Hotspur Technologies Commences US Launch at Veith/AIM Conference in New York City 2OncoSec and Serametrix Collaborate to Identify Potential Biomarkers to Enhance Skin Cancer Immune Therapies 2OncoSec and Serametrix Collaborate to Identify Potential Biomarkers to Enhance Skin Cancer Immune Therapies 3OncoSec and Serametrix Collaborate to Identify Potential Biomarkers to Enhance Skin Cancer Immune Therapies 4
Open blade speculum designed for both temporal and superior approach ocular surgery. Thumb screw adjusting mechanism. Manufactured in titanium....
Open 11 mm blades. Dull finish. Most popular size or model....
Open 5 mm blades. Dull finish. Most popular size or model....
Closed wire 5 mm blade with a wing tip twist giving the surgeon better on-axis accessibility....
Medicine Products: