At Burnham-UCSB, Ruoslahti opened the Vascular Mapping Center which focuses on developing applications for vascular "zip codes," based on technology discovered in his laboratory. Vascular zip codes are molecular signatures in blood and lymphatic vessels (vasculature) that are specific to individual tissues and disease sites. Ruoslahti has discovered ways to selectively target drugs to tumor blood vessels in mice and suppress the growth of those tumors. He has also found a way to selectively target the lymphatic vessels in tumors. The hope is that this very specific delivery of therapeutics to tumor blood and lymphatic vessels will increase the efficacy of cancer therapies and decrease side effects.
Ruoslahti joined the faculty at UCSB as an adjunct professor in the Department of Molecular, Cellular, and Developmental Biology in 2006. He is affiliated with The Burnham Institute for Medical Research, an institute that is located both at UCSB and in San Diego. This type of collaboration, involving a highly ranked university and a nonprofit, independent research institute, exemplifies the inherent value of interdisciplinary research and the enhanced potential created when two such entities join force. Ruoslahti also belongs to the faculty of UC San Diego as a distinguished professor.
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| Contact: Gail Gallessich gail.g@ia.ucsb.edu 805-893-7220 University of California - Santa Barbara Source:Eurekalert |