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Cancer research partnership between UCSF, MMRF to drive drug development
Date:5/29/2009

vering new treatment options to patients, multiple myeloma remains very difficult to treat and effective treatment options are limited," said Wolf. "By bringing to bear the expertise of UCSF in partnership with the MMRF, we are confident that the MMTI will hasten the pace at which new therapies to treat the disease are developed."

UCSF is at the forefront in advancing translational research, which is recognized as the critical weak link in medical science today. It involves moving discoveries made in the lab through the process of animal studies, animal testing and small-scale human trials to determine if a discovery warrants examination on a larger scale by a biotechnology or pharmaceutical company.

Research universities have excelled at discovering the genes and proteins and other cellular and extracellular components that underlie disease processes, but they have not had the infrastructure to investigate the potential of these components as therapeutic targets or tools. The work requires close collaboration between basic researchers, clinical researchers and clinicians.

In 2006, UCSF received a five-year, $100 million grant from the National Institutes of Health to support further development of the UCSF infrastructure for translational medicine. UCSF's existing infrastructure will enable the MMTI to begin its research efforts immediately.

"Currently, there are few translational research initiatives focused solely on multiple myeloma, so we are especially proud to support the MMRF and UCSF, and we are grateful to HHMI for its help in supporting such exciting, important science," said Stephen Grand, an MMRF board member. "The MMTI provides new hope for patients whose treatment options are limited, by enabling the swifter development of new drug candidates and increasing access to promising therapies under investigation."


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Contact: Jennifer OBrien
jobrien@pubaff.ucsf.edu
415-476-2557
University of California - San Francisco
Source:Eurekalert

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