Navigation Links
Cancer prevention: stopping cancer before it can start
Date:4/14/2008

SAN DIEGO Tapping into a growing body of knowledge about the origins and progression of cancer, researchers are now developing and testing new preventive therapies to stop it in its tracks. At the 2008 Annual Meeting of the American Association for Cancer Research, April 12-16, researchers present data on the preventive effects of celecoxib and atorvastatin and vitamin D in colorectal, prostate and breast cancer, respectively, and the relationship between diet, metabolism and the development of pancreatic cancer.


The Adenoma Prevention with Celecoxib (APC) trial: Five-year efficacy and safety results: Abstract LB-141

Colon adenoma prevention with celecoxib, a non-steroidal anti-inflammatory drug (NSAID), is effective and can be safe for patients without underlying cardiovascular risk factors, according to five-year data of a randomized phase III trial.

There has been a significant amount of negative press about Cox-2 inhibitors including celecoxib, and clearly these drugs are risky for some patients. However, our study also shows that for patients without major cardiovascular risk factors, celecoxib at low doses protects against high-risk lesions that can lead to colon cancer, said Monica Bertagnolli, M.D., associate professor of surgery at the Brigham and Womens Hospital.

Bertagnolli was the lead researcher on the Adenoma Prevention with Celecoxib (APC) trial, which enrolled 2,035 patients and randomly assigned them to 200 mg twice-daily (400 mg) of celecoxib, 400 mg twice-daily (800 mg) of celecoxib or a placebo group.

At three years, patients taking celecoxib at 400 mg had a 29 percent reduction in adenomas, a precursor to colon cancer, while those taking 800 mg had a 38 percent reduction. Advanced adenomas, which are lesions with a high-risk for cancer development, were reduced by 55 percent with 400 mg and 63 percent with 800 mg.

After three years, patients stopped taking
'/>"/>

Contact: Staci Vernick Goldberg
Staci.goldberg@aacr.org
267-646-0616
American Association for Cancer Research
Source:Eurekalert

Page: 1 2 3 4 5 6 7

Related medicine news :

1. Detecting, Diagnosing Breast Cancers
2. Calorie restriction inhibits, obesity fuels development of epithelial cancers
3. Stem Cell Marker Controls Pair of Key Cancer Pathways
4. Celebrex Plus Lipitor Could Fight Prostate Cancer
5. Celebrex-Lipitor combo may halt prostate cancer
6. Georgetown researchers find stem cell marker controls 2 key cancer pathways
7. Blood pressure drugs halt pancreatic cancer cell growth, Jefferson researchers find
8. Calorie restriction limits and obesity fuels development of epithelial cancers
9. Allegro Diagnostics Announces Publication in Cancer Prevention Research of Prediction Model for Lung Cancer Diagnosis Integrating Clinical and Genomic Features
10. NovoCure presents results from breast cancer pilot study
11. Jefferson scientists discovery may help explain smoking-pancreatic cancer link
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/3/2015)... “ BolehVPN ” was featured on NewsWatch as ... and coolest technology products available to consumers. Scott Steinberg, a ... and shared with viewers how to protect their private information. ... on computers and even more so online. It helps everyone ... over the world. In terms of work, the internet makes ...
(Date:5/3/2015)... is not too late to register to take part in the ... Been in Arnold, Missouri on May 9, 2015. Family and ... loving memory. It has benefited the renowned Brain Aneurysm Foundation each ... suffered a brain aneurysm . After two operations and five ... designed to serve as a remembrance of her and to help ...
(Date:5/2/2015)... Vancouver fencing company, QS Fencing, has recently announced ... prospective clients related to their questions on railings and gates. ... their decks and patios. While that seems like an easy ... the person rolls up their sleeve to start working. One ... finding a gate that matches it. , Instead of spending ...
(Date:5/2/2015)... We are pleased to announce the Sun ... one of the Top Workplaces of 2015. , The ... field for their ethics and standards of excellence. The ... their educational efforts. The Delray Recovery Center prides itself ... purpose – to help individuals heal from the disease ...
(Date:5/2/2015)... As a nonsurgical staple in ... face, neck and décolleté, radiofrequency energy is proving ... for the success of vulvovaginal rejuvenation. In a ... Council, ThermiGyn’s Women’s Health Clinical Advisory Board Chairman ... ThermiGyn’s temperature controlled radio frequency, specifically that of ...
Breaking Medicine News(10 mins):Health News:A Method to Keep Private Information Secure was Featured on NewsWatch Television 2Health News:Renowned Brain Aneurysm Foundation to Benefit from Arnold, Missouri’s 3rd Annual Brain Aneurysm Walk in Memory of Lissa Anne Been 2Health News:Professional Staff at QS Fencing Company Now Provides Advice on Railings and Gates 2Health News:The Delray Recovery Center Named 2015 Top Workplace 2Health News:Study Demonstrates Efficacy of Temperature Controlled Radiofrequency for Vulvovaginal Laxity 2Health News:Study Demonstrates Efficacy of Temperature Controlled Radiofrequency for Vulvovaginal Laxity 3
... 12 Tennessee-based,Shared Health, Inc., the largest ... announced today the results of a new ... following implementation of its HIE. The,efficiency improvements ... when incorporating the Shared Health solution into ...
... Dermatologist Doing His Part to Warn Consumers, OMAHA, ... has been in the news for the past several ... Fig, the,parent company for up to 18 facilities around ... procedure, has closed its stores and is,considering declaring bankruptcy. ...
... as Chairman of the Board, LIVINGSTON, N.J., Dec. ... recognized leader in,advanced injection technologies, today announced that the ... of the Company,s,medical division, as the new CEO of ... effective January 1, 2008. As CEO, Martin replaces Leonard,Osser, ...
... drug has been shown to improve the sleep quality ... the most commonly-used medication, according to research published today ... compared the effects of the new drug dexmedetomidine with ... the pain and anxiety experienced by mechanically ventilated ICU ...
... A new development in the fight against cancer: Recent ... found in common fungus Ganoderma lucidum aid in suppressing ... prostate cancer. The main action of the fungus: disrupting ... cells. , Over the past 3-4 decades much ...
... Rispler-Chaim of the Department of Arabic language and literature ... to people with various disabilities based on Muslim jurists, ... era. , In the Islamic legal literature people with ... such as religious duties, jihad, marriage, etc., but seldom ...
Cached Medicine News:Health News:New Data From Shared Health, Inc., Proves Effectiveness of Health Information Exchange for Improving Patient Outcomes at the Point of Care 2Health News:Will Lipodissolve Continue to Remain Popular? 2Health News:Joe Martin Appointed CEO of Milestone Scientific and New Executive Member of the Board of Directors 2Health News:Joe Martin Appointed CEO of Milestone Scientific and New Executive Member of the Board of Directors 3Health News:Intensive care quality of sleep improved by new drug, reports study 2Health News:Active compounds found in Ganoderma lucidum fungus with potential to treat prostate cancer 2
(Date:5/1/2015)... , May 1, 2015  Thoratec Corporation (NASDAQ: ... to save, support and restore failing hearts, announced today that ... created role of President, International. This new ... commercial operations outside of North America , ... , and Latin America , and reports ...
(Date:5/1/2015)... Calif. , May 1, 2015 The ... its 2015 health literacy award winners. The IHA Health ... that make an impact on the practice of educating ... health literacy. IHA gives awards in three categories: innovative ... bestowed its Health Literacy Hero award. In ...
(Date:5/1/2015)... , May 1, 2015 Semler Scientific, Inc. ... company that develops, manufactures and markets products that assist ... today reported financial results for the first quarter ended ... quarter of 2015, Semler reported continued progress with year ... quarter revenue growth of 14%," said Doug Murphy-Chutorian ...
Breaking Medicine Technology:Thoratec Announces Addition To Senior Management Team 2Thoratec Announces Addition To Senior Management Team 3Institute for Healthcare Advancement Announces 2015 Award Winners 2Semler Reports First Quarter 2015 Financial Results 2Semler Reports First Quarter 2015 Financial Results 3Semler Reports First Quarter 2015 Financial Results 4Semler Reports First Quarter 2015 Financial Results 5
SPIRAL-FLEX® Oral Precut Reinforced Tubes...
Pre-Loaded with a Stylet., ,Available Cuffed or Uncuffed, pre-loaded with a stylet to facilitate quick intubations....
... cuff., ,Sheridan Endotracheal Tubes offer the ... level of tactile feedback from pilot balloon ... soften at body temperature , Smooth tube ... trauma during intubation , Two distinct cuff ...
Adult (ICU) Tracheal Tubes with Micro-thin-walled cuffs....
Medicine Products: