Navigation Links
Cancer in the elderly: Research fails to keep up with demographic change
Date:5/11/2012

the best way of selecting patients for specific treatment, says Professor Sebag-Montefiore.

"Although a patient's treatment should not be determined purely on the basis of age, we need to take into account the fact that things like the length of treatment, which often takes place over five to six weeks, and the travel time to cancer centres can weigh much more heavily on an older person. And although most trials do not have an upper age limit, many studies exclude patients with co-morbidities and usually the median age in such trials is significantly lower than that of the general population. So we need to design studies urgently to address these problems if we are to be able to provide the best evidence-based treatment to an ageing population," he says.

Chemotherapy also poses problems for older people, says Dr. Laura Biganzoli, from the Hospital of Prato, Istituto Toscano Tumori, Prato, Italy. "Recommendations for treatment are largely based on limited retrospective subgroup analyses from larger trials and the extrapolation of study results from younger patients. This is clearly inappropriate, since breast cancer biology differs in older patients, treatment tolerance varies, and there are the ever-present problems of co-morbidities."

Only two published studies have prospectively evaluated the role of chemotherapy in elderly breast cancer patients, and a retrospective study has found a higher risk of treatment-related deaths in older women. "In addition to the lack of clinical trials dedicated to older patients," says Dr. Biganzoli, "we also need to design studies for those who are vulnerable and frail."

In radiotherapy under-treatment after breast conserving surgery is common, she says. "The CALGB [3] trial 9343 showed that not giving radiotherapy to women with early stage breast cancer with oestrogen receptor positive tumours who had breast conserving surgery and were taking tamoxifen had no impact on survival but was assoc
'/>"/>

Contact: Mary Rice
mary.rice@riceconseil.eu
European Society for Radiotherapy and Oncology (ESTRO)
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. Many Young Adults at Risk of Skin Cancer: CDC
2. Genetic predictor of breast cancer response to chemotherapy
3. Stem cell sparing radiotherapy for head and neck cancer may avoid salivary gland damage
4. Infection Causes 1 in 6 Cancers Worldwide: Study
5. Soybeans soaked in warm water naturally release key cancer-fighting substance
6. Editorial calls for comprehensive approach to cancer screening
7. Mayo Clinic: Exhaustion renders immune cells less effective in cancer treatment
8. Exercise May Boost Survival in Breast, Colon Cancer Patients
9. Mystery of the missing breast cancer genes
10. Physical activity linked to reduced mortality in breast and colon cancer patients
11. UC Irvine study finds racial, economic disparities in ovarian cancer care, survival
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/6/2015)... 2015 MJNational LLC strengthens its consultant ... Canna Bizcard ™ platform. This exciting new SMS platform ... Product Sales / Services. Now you can reach ... to products, services and ticker symbol through an easy ... MJNational LLC will provide managed support and services to ...
(Date:5/6/2015)... (PRWEB) May 06, 2015 A quality built chicken ... a functional yet practical way to raise chickens on a pasture. ... Chicken Coop Condo, it will have a chicken tractor that stands ... last for many years, as it is able to flex to ... which areas of the land are fertilized, and it will help ...
(Date:5/6/2015)... The Canton Group is joining Lardarius ... 6th annual charity softball game. The event takes place on ... Stadium. Past years guests include Joe Flacco, John Harbaugh, Ed ... on sale if you are interested in attending. , ... such as SOAR Baltimore and The CollegeBound ...
(Date:5/6/2015)... 2015 Animals make just as good friends ... good for your health. An Ohio veterinarian has ... he's seeing with health advantages of owning a pet. , ... comes to pet ownership, there are proven health benefits for ... Leffler of the Animal Medical Center of Streetsboro ...
(Date:5/6/2015)... 2015 Anitha Nallari, MD has ... Consultants, Inc. in Columbus, OH. Dr. Nallari will see ... focus in breast cancer, lung cancer, GI and gallbladder cancer, ... as benign hematology. , Dr. Anitha Nallari is ... the American Board of Internal Medicine. She completed her medical ...
Breaking Medicine News(10 mins):Health News:Cannabiz Mobile Inc. Launches the Canna Bizcard ™ Platform to Support to Cannabis Market 2Health News:Cannabiz Mobile Inc. Launches the Canna Bizcard ™ Platform to Support to Cannabis Market 3Health News:Chicken Coop Condo Launches the Chicken Tractor 2Health News:The Canton Group Sponsors Ravens Charity Softball Event 2Health News:The Canton Group Sponsors Ravens Charity Softball Event 3Health News:Veterinarian Supports 2015 HABRI Study Citing Increase in Health Advantages of Pet Owners 2Health News:Veterinarian Supports 2015 HABRI Study Citing Increase in Health Advantages of Pet Owners 3Health News:New Oncologist to Join Hematology Oncology Consultants, Inc. 2Health News:New Oncologist to Join Hematology Oncology Consultants, Inc. 3
... It took 12 years and a creation of a highly ... Jefferson have finally proven a long suspected theory: Inflammation in ... breast cancer. In the December 15 issue of ... show that an inflammatory process within the breast itself promotes ...
... By Karen Pallarito HealthDay Reporter , TUESDAY, ... that struck down a key component of the new U.S. ... insurance -- marks the first successful challenge to the controversial ... which has pitted President Barack Obama and fellow Democrats against ...
... sociologists have developed a device to gather more ... teenagers and young adults than conventional face-to-face interviews ... group,s new nonverbal response card allows respondents to ... of sociology David Lindstrom and Dennis Hogan, and ...
... other people is scary. One way to respond to this is ... to them. But there,s another common response, according to a new ... Association for Psychological Science. The researchers found that people who believe ... the victim,s life more meaning. "A lot of the ...
... Laboratory culture (in vitro) studies examining the activity of ... of central nervous system aging, injury and disease, have ... that enhances survival and maturation of hippocampal neurons harvested ... "As we age, cognitive function tends to decline," said ...
... JOLLA, CA-A close collaboration between researchers at the Salk ... Study found that the tumor suppressor p53, long thought ... more than thwart cancer-causing mutations. It may also prevent ... stem-like state by serving as a "Guardian against Genome ...
Cached Medicine News:Health News:Breast inflammation is key to cancer growth, Kimmel Cancer Center researchers say 2Health News:Health-Care Reform Faces Long Legal Fight 2Health News:Health-Care Reform Faces Long Legal Fight 3Health News:Health-Care Reform Faces Long Legal Fight 4Health News:New survey device gets better information on teenage sexual behavior 2Health News:New survey device gets better information on teenage sexual behavior 3Health News:People who believe in justice also see a victim's life as more meaningful after tragedy 2Health News:Human umbilical cord blood cells found to enhance survival and maturation of key brain cells 2Health News:The stemness of cancer cells 2Health News:The stemness of cancer cells 3
(Date:5/6/2015)... 2015 CVS Health (NYSE: CVS ) officially announced ... locations that sustained heavy fire damage during protests last week.  ... Baltimore over the past week or so, our hearts ... CVS Health President and CEO Larry Merlo . "Our purpose ... health. There is no better way that we can fulfill that ...
(Date:5/6/2015)... , May 06, 2015 Research and Markets ... addition of the "Cannulas Market by Product ... Infusion, Venous, Microcannula), Material (Plastic, Metal) & End ... to 2020" report to their offering. ... grow at a CAGR of 5.6% from 2015 ...
(Date:5/6/2015)... , May 6, 2015  Rigrodsky & Long, P.A.: ... Pharmaceuticals, Inc. (NASDAQ GM: AERI )? , Did you ... inclusive? , Did you lose money in your investment in ... rights? Rigrodsky & Long, P.A. , ... , announces that a complaint has been filed in the United ...
Breaking Medicine Technology:CVS Health Announces it Will Rebuild Baltimore CVS/pharmacy Locations 2Global Cannulas Market 2015 - Forecasts to 2020 with Medtronic, Edward Lifesciences, Terumo, Sorin & Maquet Holding B.V. & Co. Dominating 2Global Cannulas Market 2015 - Forecasts to 2020 with Medtronic, Edward Lifesciences, Terumo, Sorin & Maquet Holding B.V. & Co. Dominating 3SHAREHOLDER ALERT: Rigrodsky & Long, P.A. Announces A Securities Fraud Class Action Lawsuit Has Been Filed Against Aerie Pharmaceuticals, Inc. 2SHAREHOLDER ALERT: Rigrodsky & Long, P.A. Announces A Securities Fraud Class Action Lawsuit Has Been Filed Against Aerie Pharmaceuticals, Inc. 3
Subretinal Fluid Cannula, Curved; 20g (0.90) x 1-1/2" (38mm); 12mm Flexible Tubing Extends 6mm Beyond Tip; Curved at 65°....
Silicone Oil Cannula; 16g (1.40) x 8mm....
Micro Vitreoretinal Cannula; Angled; 20g (0.90) x 1" (25mm); Tip Extension: 3mm, 32g (0.23); Angled at 65°, 1mm from Tip....
...
Medicine Products: