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Cancer cells revert to normal at specific signal threshold, Stanford researchers find
Date:6/30/2008

ff a little bit, or for a little time, and that's enough to have a profound effect on cancer," Felsher said.

The multidisciplinary research team that conducted the work included 14 scientists from seven different Stanford departments.

The study's results will be used to design future cancer treatments, the team said. At present, no drugs target Myc. Understanding the Myc threshold will make it easier to design new drugs that focus on Myc itself or target other key signals required to switch from tumor to healthy cells. Armed with a detailed profile of cellular changes near the Myc threshold, researchers now have a much better idea of where to look for new cancer treatments. "It allowed us to narrow down the hunt," Felsher said.


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Contact: Erin Digitale
digitale@stanford.edu
650-724-9175
Stanford University Medical Center
Source:Eurekalert

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