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Cancer Drugs May Treat Type 1 Diabetes
Date:11/18/2008

etes, he said.

Teodora Staeva, from the Juvenile Diabetes Research Foundation International, thinks the results of the study are important, but whether the drugs can treat diabetes in people safely still has to be established.

"What is exciting is that this is a new class of compounds to modulate autoimmunity," Staeva said. "The findings here suggest that they may be potentially useful in type 1 diabetes."

Staeva noted that other drugs have been able to reverse diabetes, but when the drug is stopped, the disease comes back immediately. "What is encouraging here is that when they stopped the 10-week regimen, they still see a prolonged remission from the disease," she said.

Despite these encouraging findings, Staeva isn't sure how well the results will translate into human diabetics. "The biggest unknown right now is the safety," she said.

"Where one is not dealing with a life/death situation, one has to be much more careful about the potential safety of the drug," she said.

More information

For more about type 1 diabetes, visit the Juvenile Diabetes Research Foundation International.



SOURCES: Jeffery Bluestone, Ph.D., University of California, San Francisco, Diabetes Center; Teodora Staeva, Ph.D., Juvenile Diabetes Research Foundation International, New York City; Nov. 17-21, 2008, Proceedings of the National Academy of Sciences, online


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