Navigation Links
Cancer Drug Appears to Help With Aggressive MS
Date:6/12/2008

Use of cyclophosphamide sees 87% improvement in physical, mental function, study says

THURSDAY, June 12 (HealthDay News) -- High doses of a drug used to fight cancer may reduce disease activity and disability in people with aggressive multiple sclerosis, results of a small trial suggest.

In relapsing-remitting MS, the most common type of the disease, patients experience periods of symptoms followed by stretches of symptom-free remission when they used the immunosuppressant drug cyclophosphamide.

In the two-year open label trial that included nine patients with aggressive relapsing-remitting MS, six men and three women with the average age of 35, received 50 milligrams per kilogram per day of cyclophosphamide intravenously for four consecutive days.

After an average of 23 months follow-up, the patients experienced an average 39.4 percent reduction in disability and an 87 percent improvement on scores of physical and mental function. MRI imaging showed a decrease in the average number of MS-related brain lesions, from 6.5 to 1.2 lesions.

"High-dose cyclophosphamide (sold commercially as Cytoxan or Neosar) induced a functional improvement in most of the patients we studied," wrote lead author Chitra Krishnan of the Bloomberg School of Public Health at Johns Hopkins University in Baltimore, Md. "In many of those patients, the functional improvement was sustained through the length of the study (up to 24 months) despite the absence of any immunomodulatory therapies beyond the initial high-dose cyclophosphamide treatment," she concluded.

The study was published online this week in the journal Archives of Neurology and was expected to be in the August print issue.

Cyclophosphamide has been used in combatting a number of cancers, including lymphomas, multiple myeloma, leukemia, mycosis fungoides, neuroblastoma, ovarian carcinoma, retinoblastoma and breast cancer. The drug affects th
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Conventional prognostic factors fail to explain better prostate cancer survival in most Asian men
2. Survival differences by race most apparent in advanced stages of breast cancer
3. MRI finds breast cancer before it becomes dangerous
4. Investigators uncover intriguing clues to why persistent acid reflux sometimes turns into cancer
5. Pathway links inflammation, angiogenesis and breast cancer
6. Radiologists encouraged to look beyond cancer for clinically unseen diseases
7. Diet high in meat, fat and refined grains linked to risk for colon cancer recurrence, death
8. Immune deficiency linked to a type of eye cancer
9. Drop in breast cancer incidence linked to hormone use, not mammograms
10. Breast cancer prevention practices vary across Canada
11. First biomarker discovered that predicts prostate cancer outcome
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Cancer Drug Appears to Help With Aggressive MS
(Date:9/17/2014)... September 17, 2014 Dr. Shervin Naderi, ... surgeons, has been recognized as a recipient of the 2014 ... only the best of the best as it honors physicians ... Dr. Naderi, who is affectionately known by his plastic surgeon ... handful of true rhinoplasty specialist surgeons in the ...
(Date:9/17/2014)... Steven Reinberg HealthDay Reporter ... The number of Americans dying from accidental overdoses of ... health officials reported Tuesday. Deaths from overdoses of ... climbed from 1.4 per 100,000 people to 5.4 ... Control and Prevention. That means about 3,000 people ...
(Date:9/17/2014)... one can say whether yoga provides clinical benefits to ... in the Journal of Psychiatric Practice , researchers ... with the condition who practice yoga. What the collective ... help, but it sometimes carries risks, too. , "There ... disorder," said lead author Lisa Uebelacker, associate professor (research) ...
(Date:9/17/2014)... (PRWEB) September 17, 2014 A  recent ... of a 24-year-old man named Advait Thakur who had ... caused by degenerative disc disease. This disease led to ... his nerve roots and causing severe pain. Leading spine ... and how it can lead to such severe pain, ...
(Date:9/17/2014)... 2014 The disability rights group Not Dead ... vigil against the World Federation of Right to Die Societies ... American group Final Exit Network is hosting the meeting, which ... group has scheduled a rally to open the protest vigil ... PM. , ”We are here to contradict the message of ...
Breaking Medicine News(10 mins):Health News:Vitals Honors Dr. Shervin Naderi With Top 10 Doctor Award 2Health News:Vitals Honors Dr. Shervin Naderi With Top 10 Doctor Award 3Health News:Deaths From Narcotic Painkillers Quadrupled in Past Decade: CDC 2Health News:Deaths From Narcotic Painkillers Quadrupled in Past Decade: CDC 3Health News:Survey finds benefits, risks of yoga for bipolar disorder 2Health News:Survey finds benefits, risks of yoga for bipolar disorder 3Health News:24-Year-Old Back in College After Degenerative Disc Disease Kept Him Out 2Health News:24-Year-Old Back in College After Degenerative Disc Disease Kept Him Out 3Health News:Disability Rights Activists to Protest International Euthanasia Group Meeting in Chicago 2
... VILLAGE, Calif., Feb. 27 Riverview Medical,Center, ... recognized for service,excellence under the J.D. Power ... a strong commitment by Riverview,Medical Center to ... (Logo: http://www.newscom.com/cgi-bin/prnh/20050527/LAF028LOGO-a ), The service ...
... BOSTON, Feb. 27 Although,physician-scientists and supplement manufacturers ... sparring over multivitamins. In fact, half the,physicians on ... taking a,multivitamin themselves. In recent years, Harvard Men,s ... that even if they don,t,help, they won,t hurt. ...
... The Association for Professionals in Infection Control and ... selected by Blue Shield of California Foundation (BSCF) ... healthcare-associated infections (HAIs). , APIC will join BSCF ... Foundations innovative California Healthcare-Associated Infection Prevention Initiative to ...
... Arthritis Foundation to Launch the ,I ... Can with RA in the Kitchen(TM), Campaign, NEW ... approach to cooking, which involves using 70 percent,store-bought items and ... millions of busy Americans. Unknown to most, Lee,s signature,style was ...
... Feb. 27 /PRNewswire-FirstCall/ - (Imaging Dynamics Company,Ltd.) (TSX: ... image,quality and value, today announced that it was ... digital radiography system. This is the 7th,U.S. patent ... awarded to IDC in,countries around the world for ...
... that is an early indicator of kidney dysfunction in ... of Georgia researchers have found. , Microalbuminuria, excessive amounts ... among diabetics, says Dr. Gregory Harshfield, director of the ... reason, the few studies that have looked at adolescent ...
Cached Medicine News:Health News:J.D. Power and Associates Reports: Riverview Medical Center Recognized for Providing an Emergency Department Experience 2Health News:J.D. Power and Associates Reports: Riverview Medical Center Recognized for Providing an Emergency Department Experience 3Health News:It's Time to Reassess the Value, Safety of Multivitamin Use, Says Harvard Men's Health Watch 2Health News:Celebrity Chef Sandra Lee Offers Recipes and Shortcuts in the Kitchen to People with Rheumatoid Arthritis 2Health News:Celebrity Chef Sandra Lee Offers Recipes and Shortcuts in the Kitchen to People with Rheumatoid Arthritis 3Health News:Celebrity Chef Sandra Lee Offers Recipes and Shortcuts in the Kitchen to People with Rheumatoid Arthritis 4Health News:Celebrity Chef Sandra Lee Offers Recipes and Shortcuts in the Kitchen to People with Rheumatoid Arthritis 5Health News:Celebrity Chef Sandra Lee Offers Recipes and Shortcuts in the Kitchen to People with Rheumatoid Arthritis 6Health News:IDC receives patent on dual energy imaging technology 2Health News:IDC receives patent on dual energy imaging technology 3Health News:Urine protein may be present before hypertension diagnosis in at-risk adolescents 2
(Date:9/17/2014)... MILL VALLEY, Calif. , Sept. 17, 2014 ... a partnership in the fight against sarcoma. Under ... Alliance Suzanne Renee Leider Memorial Assistance Fund. ... to reimburse sarcoma patients for expenses directly related ... specialist. Scientific literature reinforces the importance of this ...
(Date:9/17/2014)... Sept. 17, 2014  Soligenix, Inc. (OTCQB: SNGX) ... developing products that address unmet medical needs in ... today that agreement has been reached with the ... design of a pivotal, Phase 3 clinical trial ... treatment of cutaneous T-cell lymphoma (CTCL).  ...
(Date:9/16/2014)... Massachusetts , 17. September 2014 ... HOLX ), hat heute die ... zur präanalytischen Probenverarbeitung, in Europa bekannt ... gekennzeichnete, vollautomatisierte Universalplattform zur Vereinfachung der ... dass ineffiziente und fehlerbehaftete Arbeitsschritte bei ...
Breaking Medicine Technology:Champions Oncology Partners with Sarcoma Alliance to Bring Personalized Treatment Options to Sarcoma Patients 2Champions Oncology Partners with Sarcoma Alliance to Bring Personalized Treatment Options to Sarcoma Patients 3Soligenix Announces FDA Clearance of Phase 3 Clinical Protocol of SGX301 in Cutaneous T-Cell Lymphoma 2Soligenix Announces FDA Clearance of Phase 3 Clinical Protocol of SGX301 in Cutaneous T-Cell Lymphoma 3Soligenix Announces FDA Clearance of Phase 3 Clinical Protocol of SGX301 in Cutaneous T-Cell Lymphoma 4Soligenix Announces FDA Clearance of Phase 3 Clinical Protocol of SGX301 in Cutaneous T-Cell Lymphoma 5Soligenix Announces FDA Clearance of Phase 3 Clinical Protocol of SGX301 in Cutaneous T-Cell Lymphoma 6Soligenix Announces FDA Clearance of Phase 3 Clinical Protocol of SGX301 in Cutaneous T-Cell Lymphoma 7Hologic stellt in Europa den Tomcat vor, ein neues Gerät zur präanalytischen Probenverarbeitung 2Hologic stellt in Europa den Tomcat vor, ein neues Gerät zur präanalytischen Probenverarbeitung 3
... Inspiration Biopharmaceuticals, Inc. (Inspiration), the only ... of new treatment options for people with hemophilia, is ... as Chief Executive Officer. Mr. Butler replaces Michael Griffith, ... Officer and is retaining the title of President at ...
... 11, 2011 Questcor Pharmaceuticals, Inc. (NASDAQ: QCOR ... financial results on Tuesday, October 25, 2011 after the close ... conference call and slide presentation via webcast on Tuesday, October ... to discuss results and highlights of the third quarter, as ...
Cached Medicine Technology:Inspiration Biopharmaceuticals Names John P. Butler Chief Executive Officer 2Inspiration Biopharmaceuticals Names John P. Butler Chief Executive Officer 3Questcor to Report Third Quarter 2011 Earnings and Conduct Conference Call on October 25, 2011 2
... Accu-Temp Cauteries provide a ... for cauterization in a wide ... single use cautery is packaged ... cap to lock switch in ...
... provide a broad selection of tip ... variety of ophthalmic procedures. Each single ... with a safety cap to lock ... when not in use, and carries ...
... Cauteries provide a broad selection of ... wide variety of ophthalmic procedures. Each ... complete with a safety cap to ... position when not in use, and ...
... Luminary LASIK Light Probes provide the surgeon ... the corneal interface to be easily visualized ... the Tindal effect and light scatter technique, ... debris, epithelial deposits, flap edge folds, corneal ...
Medicine Products: