Navigation Links
Cancer Cells in Bloodstream Show Great Diversity: Study
Date:5/8/2012

TUESDAY, May 8 (HealthDay News) -- There is a great deal of genetic diversity in cells shed by cancerous tumors into the bloodstream, a new study has found.

Some cells have genes that enable them to lodge themselves in new locations, helping the cancer spread between organs, while other cells have different patterns of gene expression that might make them more benign or less likely to survive in other locations in the body.

Some circulating tumor cells even express genes that could predict their response to a specific cancer treatment, the researchers said.

"Within a single blood draw from a single patient, we're seeing [varied] populations of circulating tumor cells," senior study author Dr. Stefanie Jeffrey, chief of surgical oncology research at the Stanford University School of Medicine, said in a university news release.

The researchers said their findings highlight how multiple types of treatment may be needed to cure what appears to be a single kind of cancer and suggest that the current cell-line models of human cancers need to be improved upon.

The study, which used blood samples from breast cancer patients, is the first to look at circulating tumor cells one by one instead of taking the average of many of the cells. It also is the first to show the extent of genetic differences between circulating tumor cells, the researchers said.

Scientists have long known that circulating tumor cells move through the bloodstreams of cancer patients. Over the past five years, though, many cancer researchers have begun to think the cells could be the key to tracking tumors noninvasively.

The study appears online Tuesday in the journal PLoS One.

More information

The U.S. National Cancer Institute has more about cancer.

-- Robert Preidt

SOURCE: Stanford University, news release, May 7, 2012


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Enhancing arrest of cell growth to treat cancer in mice
2. Paxil Blocks Tamoxifen, Lowers Survival Odds Against Breast Cancer
3. The National Coalition for Cancer Survivorship Joins the Commission on Cancer
4. Low forms of cyclin E reduce breast cancer drugs effectiveness
5. Racial disparities persist in the diagnosis of advanced breast cancer and colon cancer in the U.S.
6. Soft drinks may increase risk of pancreatic cancer
7. UH Case Medical Center researchers publish promising findings for advanced cervical cancer
8. Genes Play Role in Prognosis With Non-Small Cell Lung Cancers
9. Single gene mutation induces endometrial cancer
10. Certain genetic profiles associated with recurrence-free survival for non-small cell lung cancer
11. Molecular pathways linked to sex, age affect outcomes in lung cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Cancer Cells in Bloodstream Show Great Diversity: Study
(Date:4/21/2017)... TX (PRWEB) , ... April 21, 2017 , ... ... Care products, announced an exciting new partnership with the highly regarded and well ... Airway Management’s highly innovative, myTAP & myTAP PAP Nasal Pillow Mask, and will ...
(Date:4/21/2017)... Malvern, Worcestershire, UK (PRWEB) , ... April 21, ... ... Queen’s Award for Enterprise in the category of International Trade, the UK’s most ... performance in international trade, which represents 95% of total revenues and has grown ...
(Date:4/21/2017)... Ramon, CA (PRWEB) , ... April 21, 2017 , ... ... might not understand the estate planning process, or where to even begin. “Now more ... unresolved if you are to properly protect yourself and your family,” said attorney Lisa ...
(Date:4/21/2017)... , ... April 21, 2017 , ... Westside Dental ... personalized dental care since 1985. After thirty-two years, Dr. Latner has become one of ... help my numerous clients over the years with all their dental needs,” said Dr. ...
(Date:4/21/2017)... (PRWEB) , ... April 21, 2017 , ... Each year, ... is a day to clean, plant trees and look forward to a better future. ... just about doing something outdoors. Indoor air quality can be two to five times ...
Breaking Medicine News(10 mins):
(Date:4/19/2017)... Calif. , April 19, 2017  IRIDEX Corporation ... will release financial results for the first quarter 2017 ... 2017.  The Company,s management team will host a corresponding ... p.m. ET. Investors interested in listening to ... 707-0665 for domestic callers or (703) 326-3030 for international ...
(Date:4/19/2017)... -- The Global Effective Microorganisms (EM) Market by ... covered and analysed the potential of Global Effective Microorganisms (EM) ... and growth factors. The report identifies and analyses the emerging ... global market. ... Tables and Figures, 6 Major Company Profiles, spread across 124 ...
(Date:4/19/2017)... 19, 2017  Novartis today announced the publication ... Lung, and Blood Institute (NHLBI) of the National ... patients with treatment-naïve severe aplastic anemia (SAA) achieved ... eltrombopag at the initiation of and concurrently with ... three sequential treatment groups, or cohorts. Cohort 3 ...
Breaking Medicine Technology: