Navigation Links
Cancer Cells in Bloodstream Show Great Diversity: Study
Date:5/8/2012

TUESDAY, May 8 (HealthDay News) -- There is a great deal of genetic diversity in cells shed by cancerous tumors into the bloodstream, a new study has found.

Some cells have genes that enable them to lodge themselves in new locations, helping the cancer spread between organs, while other cells have different patterns of gene expression that might make them more benign or less likely to survive in other locations in the body.

Some circulating tumor cells even express genes that could predict their response to a specific cancer treatment, the researchers said.

"Within a single blood draw from a single patient, we're seeing [varied] populations of circulating tumor cells," senior study author Dr. Stefanie Jeffrey, chief of surgical oncology research at the Stanford University School of Medicine, said in a university news release.

The researchers said their findings highlight how multiple types of treatment may be needed to cure what appears to be a single kind of cancer and suggest that the current cell-line models of human cancers need to be improved upon.

The study, which used blood samples from breast cancer patients, is the first to look at circulating tumor cells one by one instead of taking the average of many of the cells. It also is the first to show the extent of genetic differences between circulating tumor cells, the researchers said.

Scientists have long known that circulating tumor cells move through the bloodstreams of cancer patients. Over the past five years, though, many cancer researchers have begun to think the cells could be the key to tracking tumors noninvasively.

The study appears online Tuesday in the journal PLoS One.

More information

The U.S. National Cancer Institute has more about cancer.

-- Robert Preidt

SOURCE: Stanford University, news release, May 7, 2012


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Enhancing arrest of cell growth to treat cancer in mice
2. Paxil Blocks Tamoxifen, Lowers Survival Odds Against Breast Cancer
3. The National Coalition for Cancer Survivorship Joins the Commission on Cancer
4. Low forms of cyclin E reduce breast cancer drugs effectiveness
5. Racial disparities persist in the diagnosis of advanced breast cancer and colon cancer in the U.S.
6. Soft drinks may increase risk of pancreatic cancer
7. UH Case Medical Center researchers publish promising findings for advanced cervical cancer
8. Genes Play Role in Prognosis With Non-Small Cell Lung Cancers
9. Single gene mutation induces endometrial cancer
10. Certain genetic profiles associated with recurrence-free survival for non-small cell lung cancer
11. Molecular pathways linked to sex, age affect outcomes in lung cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Cancer Cells in Bloodstream Show Great Diversity: Study
(Date:5/26/2016)... ... 26, 2016 , ... On Memorial Day, Hope For Heroes and ... military battle for the country. The nonprofit Hope For Heroes partnered with the ... empower independence for disabled military veterans, as well as police, firemen, and EMS professionals ...
(Date:5/26/2016)... ... 26, 2016 , ... There are nearly 14.5 million people living with and ... On Sunday, June 5, 2016, communities around the world will gather to recognize these ... National Cancer Survivors Day® is an annual worldwide Celebration of Life that is held ...
(Date:5/26/2016)... ... May 26, 2016 , ... Dr. James Maisel will ... Long Island Chapter on June 4, 2016, 1:30-3:30 pm at the Farmingdale Public ... Retina Group of New York , is a Board Certified ophthalmologist who ...
(Date:5/26/2016)... R.I. (PRWEB) , ... May 26, 2016 , ... Memorial ... That’s why Amica Insurance is sharing tips to make sure your family ... estimate from the National Safety Council, there may be 439 deaths and an additional ...
(Date:5/26/2016)... ... May 26, 2016 , ... The Lung Institute has partnered ... cessation class starting June 6 at their clinic in downtown Tampa. The class is ... the Lung Institute has created a free downloadable 4 Week Smoking Cessation Guide ...
Breaking Medicine News(10 mins):
(Date:5/25/2016)... , May 25, 2016 According ... by Type (3D, 2D, 4D), by Therapeutic Area (Oncology, ... End User (Medical Device Manufacturers, Hospitals/ Clinics) - Forecast ... global Medical Animation Market for the forecast period of ... USD 301.3 Million by 2021 from USD 117.3 Million ...
(Date:5/25/2016)... , May 25, 2016  According to Kalorama Information, ... billion in 2015.  Though these are challenging times ... opportunity for success for companies that remain optimistic ... of new growth prospects medical device companies spend ... and development (R&D) than do companies in other ...
(Date:5/25/2016)... Texas , May 25, 2016 ... the issuance to it by the US Patent ... The company,s technology includes proprietary processes for electronic ... for health and wellness programs, HIPAA compliance and ... "Our technology ...
Breaking Medicine Technology: