Navigation Links
Canadian researchers discover the first-ever link between intelligence and curiosity
Date:9/15/2009

TORONTO, Sept. 15 /PRNewswire/ - Scientists from the Samuel Lunenfeld Research Institute of Mount Sinai Hospital in Toronto have discovered a molecular link between intelligence and curiosity, which may lead to the development of drugs to improve learning.

In a paper, published in Neuron, Dr. John Roder, Senior Investigator at the Lunenfeld, and Bechara Saab, Ph.D candidate at the Lunenfeld, studied the interaction of two proteins in a small region of the brain called the dentate gyrus (part of the hippocampus, which plays a role in long-term memory and spatial navigation).

For the study, the neuronal calcium sensor-1 (NCS-1), a protein which is known to affect the memory of worms and is linked to bipolar and schizophrenia in people, was increased by one-and-a-half fold specifically in the dentate gyrus of mouse models. This modest overexpression increased the ability of brain cells to change how they communicate with each other and gave the mice superior memory in complex tasks and a significant increase in exploratory behaviour (curiosity). Because the exploratory behaviour was only altered in safe environments, Dr. Roder and Saab believe they have discovered a region of the brain that generates curiosity and a model for how brain activity leads to curiosity.

The researchers also discovered that both curiosity and spatial memory were impaired when a benign drug blocked the NCS-1 protein from binding to the dopamine type-2 receptors (a major target of anti-psychotics) in the dentate gyrus.

"Now that we know that some of the molecules and brain regions that control learning and memory also control curiosity, we can go back to the lab and design drugs that may improve cognition in humans - that's the potential benefit for the future," explains Saab. "Immediately, however, we can put into use the knowledge that fostering curiosity should also foster intelligence and vice versa."

The study was funded by the Canadian Instit
'/>"/>

SOURCE Mount Sinai Hospital
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2

Related medicine news :

1. Queens study to test Canadian guidelines for daily exercise
2. Elsevier and Canadian College of Health Service Executives announce new publishing partnership
3. NeuroVasx Receives Canadian Approval for cPAX Aneurysm Treatment System
4. Canadians Travel to Detroit Town Meeting to Talk About Their Health Care
5. The National Health Care Anti-Fraud Association Signs Memorandum of Understanding With Canadian and European Anti-Fraud Organizations
6. Narconon Trois-Rivieres Cites Hillbilly Heroin as Canadian Drug Addiction Crisis
7. Canadian Bio Med Attacks Worlds Leading Cause of Blindness
8. Live Broadcast of Drug Rehab Graduation at Canadian Narconon
9. Purolator USA Offers Canadian Customs Expertise for Medical Device Exports
10. Streamline Health Document Workflow Solution to be Integrated Into Electronic Medical Records System for Leading Canadian Healthcare Region
11. iUniverse Hosts Canadian Storytellers, Cystic Fibrosis Awareness Advocate for BookExpo America 2009 Book Signings
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/27/2014)... Recently, DressVe , the well-known trendy ... Sales, which are valid during Nov. 29 – Dec. 3 ... these new dresses, up to 90% off. In addition, free ... view more at http://www.dressve.com/ , Dresses that combine ... way to showcase somebody’s personality and figure. The designers of ...
(Date:11/27/2014)... Caicos Islands; BWI (PRWEB) November 28, 2014 ... Tuscany Resort in the Turks & Caicos. This ... TripAdvisor in Providenciales, is announcing a few highly sought ... villa rentals. And they are offering every seventh ... , Additionally, The Tuscany, is having a January 2015 ...
(Date:11/27/2014)... 27, 2014 Luciana Lagana and ... part of Omadox, a feature film that received 9 awards ... for best ensemble cast. It is also an official selection ... start to a successful cinematic career for James Noel, a ... If you enjoy experimental mystery, filmed in glorious black and ...
(Date:11/27/2014)... PITTSBURGH, PA (PRWEB) November 27, 2014 ... suffer the embarrassing side effects of urinary incontinence," said ... to it and developed this specialized accessory to prevent ... developed the Incontinence to absorb urine leakage. This prevents ... wearer from potential embarrassment. The pad ensures that the ...
(Date:11/27/2014)... -- Thanksgiving meals can pose a challenge for people ... says. Many traditional Thanksgiving dishes -- such as ... gluten-free, but "when it comes to pies, stuffing, gravy, ... Anca Safta, director of the Gluten and Allergic Digestive ... North Carolina, said in a center news release. ...
Breaking Medicine News(10 mins):Health News:DressVe.com Introduces Its 2014 Special Monday Sales To The Global Customers 2Health News:The Tuscany on Grace Bay, Top-Rated TripAdvisor Resort in the Turks & Caicos Islands, Offers Special Pre-Christmas & January 2015 Promotions! 2Health News:Luciana Lagana and Gregory Graham Join the Award-Winning Cast of the Black-and-White Experimental Mystery Feature Film Omadox. 2Health News:Luciana Lagana and Gregory Graham Join the Award-Winning Cast of the Black-and-White Experimental Mystery Feature Film Omadox. 3Health News:Expert Shares Gluten-Free Thanksgiving Tips 2
... COLUMBUS, Ohio, Dec. 1 Seniors who take a ... Medicare Advantage plans may still realize,savings next year. ... continue,to offer $0 monthly premiums and $0 deductibles with ... pay 100% of their,drug bills until reaching $4,350 in ...
... ( www.amanzitea.com ), a unique tea bar and retailer, announced today ... 6th, it is offering free "amanzi tea flu shots" made of ... and 20th from noon until four. This is a healthy ... of winter. , , ...
... appropriately treat breast cancer in men, according to a ... Center in Houston, TX. , Image findings from ... were reviewed during the study. "The findings show that ... a mass with an irregular shape and spiculated (spiky ...
... used a new imaging technique to take high quality ... in mice, and the technology could help in the ... may cause blindness. , The study, "The Clinical Time-Course ... with Histologic and Cellular Infiltrate Correlation," was published in ...
... OAKLAND, Calif., Dec. 1 As President Bush seeks,to ... which will especially,adversely impact healthcare services and workplace safety, ... new,website inviting web browsers to help "send Bush packing,", ... The site offers an interactive game highlighting some of ...
... CHICAGO, Dec. 1 For difficult to diagnose patients,Breast-Specific ... useful adjunctive,imaging tool than ultrasound for patients who need ... presented today,at the annual meeting of the Radiological Society ... technique that can see lesions independent,of tissue density and ...
Cached Medicine News:Health News:HealthMetrix Research Finds Medicare Advantage Plans Offer Seniors Opportunity to Lower Their 2009 Out-of-Pocket Drug Costs 2Health News:Amanzi Tea offers free, natural 'Flu Shots' to New Yorkers 2Health News:New technique captures high-res images of full retina 2Health News:Citing 'Midnight Rules' to Erode Health and Safety, Nurses Unveil New Website to Send Bush Packing 2Health News:Molecular Breast Imaging Performs Better Than Ultrasound in Patients With Mammographic Abnormalities 2
(Date:11/26/2014)... Nov. 25, 2014  Breckenridge Pharmaceutical, Inc. announced ... ANDA agreement with Pii (Pharmaceutics International, Inc.) ( ... Breckenridge and Pii expect to develop and commercialize ... agreement, Pii will develop, manufacture and supply the ... products under its own label.  The drugs, comprised ...
(Date:11/26/2014)... DUBLIN , Nov. 25, 2014 Jazz Pharmaceuticals plc ... be webcasting its corporate presentations at two upcoming investor conferences.  ... London, UK on Tuesday, December 2, 2014 at ... senior vice president and head of EUSA International, will provide an ... , 26 th Annual Piper Jaffray Healthcare Conference in ...
(Date:11/26/2014)... DIEGO , Nov. 25, 2014 Halozyme Therapeutics, ... the Piper Jaffray Healthcare Conference in New York ... EDT/10:00 a.m. PDT . Dr. Helen Torley , ... The presentation will be webcast through the "Investors" ... a recording will be made available for 90 days following ...
Breaking Medicine Technology:Breckenridge Pharmaceutical signs Multi-Product Generic Agreement with Pharmaceutics International, Inc. 2Jazz Pharmaceuticals Announces Participation in Two Investor Conferences 2Halozyme Therapeutics To Present At The Piper Jaffray Healthcare Conference 2
... MUNDELEIN, Ill. , March 18 Sysmex ... and information systems developer, today announced its selection to ... Karen Stoneman , Vice President of Human Resources, Sysmex ... practice of the "10 Characteristics of a Company That ...
... the "Company"), an international biopharmaceutical company with,operations in the U.S. and China , is pleased to announce the exercise of a,warrant by a principal shareholder, RimAsia Capital ... ... ... ...
Cached Medicine Technology:Sysmex America Honored Second Consecutive Year as a 'Company That Cares' 2Sysmex America Honored Second Consecutive Year as a 'Company That Cares' 3Sysmex America Honored Second Consecutive Year as a 'Company That Cares' 4NeoStem Announces Warrant Exercise by Principal Shareholder 2NeoStem Announces Warrant Exercise by Principal Shareholder 3NeoStem Announces Warrant Exercise by Principal Shareholder 4NeoStem Announces Warrant Exercise by Principal Shareholder 5
... Wristrest is the standard for stabilization of the ... easily adjustable and its bar can be rotated ... eye. It allows the surgeon to stabilize his ... the fine finger movements necessary for eye surgery. ...
Hydroview insertion forcep with very thin jaws to allow insertion through tunnel or clear cornea incision. Locking. Made in titanium....
... most flexible intraocular lens for ease ... The notched jaws align the implant ... fold. Ideal for lens diameters from ... on tip is great for tucking ...
Titanium. Curved 18 mm shafts with 1.5 wide grasping tip. Flat, serrated cross action handle with dull finish....
Medicine Products: