Navigation Links
Canada-wide study on slow progressors to investigate new treatments for HIV
Date:2/6/2009

This press release is available in French.

Montreal, Febrauary 6, 2009 -- Why do some HIV patients manage to control the progression of their infection naturally over long periods of time? As part of a nation-wide investigation, a team of researchers will examine that question and others as they work to develop new strategies to fight AIDS.

The five-year study will be headed by Dr. Ccile Tremblay, a physician and investigator with the Centre hospitalier de l'Universit de Montral's Research Centre (CRCHUM) and a professor at the Universit de Montral, thanks to nearly $1 million in support from the Canadian Institutes for Health research (CIHR).

In light of a limited success in developing vaccine therapies, it has become clear that the scientific community needs to place greater emphasis on the basic research necessary to address the many unanswered questions that remain about HIV. One of the best approaches to try to develop effective vaccines is the study of HIV-infected individuals who control their infection naturally and do not show disease progression over a long period of time. Called slow progressors (SP), these individuals make up less than 1percent of HIV-infected population. Some of the questions that this study will address include:

  • What constitutes a protective immune response?
  • What are the drivers of HIV diversity?
  • Can we develop broadly neutralizing antibodies?
  • And, ultimately, how can this understanding lead to the development of an effective vaccine?

Conducting a study of this nature requires a sufficiently large pool of slow progessors. Enter Dr. Tremblay, whose team has assembled a unique cohort of slow progessors in Quebec and, thanks to the CIHR funding, she will expand it throughout Canada. This national effort will involve the collaboration of major HIV clinical scientists across the country, including in Toronto, Vancouver and Victoria, as well as international colleagues.

The cohort will enable researchers to gather important information concerning the clinical course of HIV, which may lead to the identification of factors that predict a favourable outcome. The study will enable the collection of samples that will be stored in a specimen bank, which will be made available to various investigators investigating the progression of HIV.

The project aims to determine the natural history of the disease over a five-year period. It will also focus on the impact of viral genetic evolution on the immune system through the collection of clinical, demographic, social and behavioural data that will be analyzed in correlation with virological, immunological and genetic findings.


'/>"/>

Contact: Nathalie Forgue
nathalie.forgue.chum@ssss.gouv.qc.ca
51-489-080-001-4342
University of Montreal
Source:Eurekalert

Related medicine news :

1. New Vivisimo Case Study Details Medical Search
2. Penn study shows how electronic medical records can be used to test drug efficacy
3. Genome Study Points to New Culprit for Schizophrenia
4. New Clinical Study Presented at the Society for Critical Care Medicine Shows Value of Pulse CO-Oximetry(TM) to Identify Acquired Methemoglobinemia
5. New Study Provides Benchmarks for Best Practices for Valuing Internal Consulting Organizations
6. MSU study finds high level of medical mistrust among minority women impacts quality of health care
7. Transition Therapeutics Announces Completion of Patient Enrolment of Phase 2 Study of TT-223 in Type 2 Diabetes Patients
8. New study raises concerns about screen time among urban children with asthma
9. Study Reveals Consumers Want to Buy Products That Dental Hygienists Recommend
10. Methamphetamine use cost the US about $23 billion in 2005, RAND study estimates
11. USC study finds that green tea blocks benefits of cancer drug
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/8/2016)... ... February 08, 2016 , ... ... newly redesigned website, federallabs.org . The site houses a wealth of federal ... federal technologies through the process called technology transfer (T2). As a network of ...
(Date:2/8/2016)... ... ... has struggled to quit smoking, a man who has struggled with hair loss – Craig ... problems – and he did. Now Nabat, a serial entrepreneur featured as the October 2015 ... the world and better people's lives. His own experience with nicotine addiction led to the ...
(Date:2/8/2016)... Indianapolis, IN (PRWEB) , ... February 08, 2016 ... ... serving the Indianapolis, IN metro area, has selected the latest beneficiary of their ... nonprofit organization dedicated to preventing bullying in area schools. Donations are now being ...
(Date:2/8/2016)... ... 08, 2016 , ... Eating disorders and post-traumatic stress disorder ... and men with eating disorders report a history of trauma, research suggests that ... an eating disorder. , At the 2016 iaedp Symposium, the workshop, “What ...
(Date:2/8/2016)... ... February 08, 2016 , ... TopConsumerReviews.com recently awarded their highest five-star rating ... Moles are derived from a cluster of melanin when exposed to sunlight. Although most ... create a lifetime of embarrassment. Historically, mole removal has involved a painful, ...
Breaking Medicine News(10 mins):
(Date:2/8/2016)... Alzheimer Diagnostic Tests - Medical Devices Pipeline Assessment, ... report , "Alzheimer Diagnostic Tests - Medical Devices ... Diagnostic Tests currently in pipeline stage. The ... with comparative analysis of the products at various ... involved in the pipeline product development. It also ...
(Date:2/8/2016)... 2016 CBG Technologies, a U.S. company, ... Recycling Systems, specifically designed for precision parts cleaning. ... and existing vapor degreasers, parts washers and ultrasonic ... continuous recycling and recovers 100% of the solvent ... --> Precision parts manufacturers benefit from this ...
(Date:2/8/2016)... 2016 --> ... "Ablation Technologies Market by Product (Radiofrequency, Ultrasound, Irreversible Electroporation, ... Surgery, Ophthalmology, Gynecology) - Global Forecasts to 2020", published ... the forecast period of 2015 to 2020. The market ... CAGR of 10.5% from 2015 to 2020. ...
Breaking Medicine Technology: