Navigation Links
Canada-wide study on slow progressors to investigate new treatments for HIV
Date:2/6/2009

This press release is available in French.

Montreal, Febrauary 6, 2009 -- Why do some HIV patients manage to control the progression of their infection naturally over long periods of time? As part of a nation-wide investigation, a team of researchers will examine that question and others as they work to develop new strategies to fight AIDS.

The five-year study will be headed by Dr. Ccile Tremblay, a physician and investigator with the Centre hospitalier de l'Universit de Montral's Research Centre (CRCHUM) and a professor at the Universit de Montral, thanks to nearly $1 million in support from the Canadian Institutes for Health research (CIHR).

In light of a limited success in developing vaccine therapies, it has become clear that the scientific community needs to place greater emphasis on the basic research necessary to address the many unanswered questions that remain about HIV. One of the best approaches to try to develop effective vaccines is the study of HIV-infected individuals who control their infection naturally and do not show disease progression over a long period of time. Called slow progressors (SP), these individuals make up less than 1percent of HIV-infected population. Some of the questions that this study will address include:

  • What constitutes a protective immune response?
  • What are the drivers of HIV diversity?
  • Can we develop broadly neutralizing antibodies?
  • And, ultimately, how can this understanding lead to the development of an effective vaccine?

Conducting a study of this nature requires a sufficiently large pool of slow progessors. Enter Dr. Tremblay, whose team has assembled a unique cohort of slow progessors in Quebec and, thanks to the CIHR funding, she will expand it throughout Canada. This national effort will involve the collaboration of major HIV clinical scientists across the country, including in Toronto, Vancouver and Victoria, as well as international colleagues.

The cohort will enable researchers to gather important information concerning the clinical course of HIV, which may lead to the identification of factors that predict a favourable outcome. The study will enable the collection of samples that will be stored in a specimen bank, which will be made available to various investigators investigating the progression of HIV.

The project aims to determine the natural history of the disease over a five-year period. It will also focus on the impact of viral genetic evolution on the immune system through the collection of clinical, demographic, social and behavioural data that will be analyzed in correlation with virological, immunological and genetic findings.


'/>"/>

Contact: Nathalie Forgue
nathalie.forgue.chum@ssss.gouv.qc.ca
51-489-080-001-4342
University of Montreal
Source:Eurekalert

Related medicine news :

1. New Vivisimo Case Study Details Medical Search
2. Penn study shows how electronic medical records can be used to test drug efficacy
3. Genome Study Points to New Culprit for Schizophrenia
4. New Clinical Study Presented at the Society for Critical Care Medicine Shows Value of Pulse CO-Oximetry(TM) to Identify Acquired Methemoglobinemia
5. New Study Provides Benchmarks for Best Practices for Valuing Internal Consulting Organizations
6. MSU study finds high level of medical mistrust among minority women impacts quality of health care
7. Transition Therapeutics Announces Completion of Patient Enrolment of Phase 2 Study of TT-223 in Type 2 Diabetes Patients
8. New study raises concerns about screen time among urban children with asthma
9. Study Reveals Consumers Want to Buy Products That Dental Hygienists Recommend
10. Methamphetamine use cost the US about $23 billion in 2005, RAND study estimates
11. USC study finds that green tea blocks benefits of cancer drug
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/22/2017)... Dallas, TX (PRWEB) , ... ... ... HCC Risk Adjustment solution leverages advanced data analytics to accurately understand each ... ensure proper reimbursement for a given population. This new solution helps transform ...
(Date:2/22/2017)... ... February 22, 2017 , ... Sideline Products participated in the World ... TV host Tom Seay and his production crew. Tom Seay’s program “Best of ... the world. Saddle Sidekicks will be featured on April 6, 2017. After the ...
(Date:2/22/2017)... ... February 22, 2017 , ... ANGLESTRONG , the new recovery management app ... the App Store and Google Play . Florida-based Sober Network, Inc., ... recovery industry, partnered with Angle to build ANGLESTRONG. The new recovery management app is ...
(Date:2/22/2017)... ... ... A product of digesting a micronutrient found in soy may hold the key ... while others do not, a University of Pittsburgh Graduate School of Public Health-led study ... some types of “good” gut bacteria when they metabolize isoflavones (micronutrients found in dietary ...
(Date:2/22/2017)... ... 22, 2017 , ... Super-Sod will attend the Athens Home Show with a ... A shift from Super-Sod’s simple Athens Home Show booth of 2016, this year’s exhibit ... plant manager Chris Roquemore constructed furniture from recycled pallet wood at the Super-Sod farm ...
Breaking Medicine News(10 mins):
(Date:2/22/2017)... and PUNE, India , February 22, 2017 ... Market Research, titled, "Automated Radio Synthesis Modules Market: Global Opportunity ... radiosynthesis modules market was worth $20 million in 2015 and ... CAGR of 6.6% from 2016 to 2022. North ... of both market revenues and unit volumes, whereas ...
(Date:2/22/2017)... , Feb 22, 2017 Research and ... Drugs Market by Drug Molecule (Biologic, Small Molecule Drugs), By ... Inhibitors, Interleukin Blockers) Outlook 2022" report to their offering. ... The ... growth during 2016-2022 This report provides a detailed ...
(Date:2/22/2017)... , Feb. 22, 2017 The Senior Care ... U.S. Senate and House of Representatives that will curtail ... Managers (PBMs) -- from extracting retroactive direct and indirect ... care (LTC) pharmacies and the Medicare program. ... (R-WV) and Jon Tester (D-MT), and ...
Breaking Medicine Technology: