Navigation Links
Canada-US scientists discover gene responsible for brain's aging
Date:1/16/2009

This press release is available in French.

Montreal, January 16, 2009 Will scientists one day be able to slow the aging of the brain and prevent diseases such as Alzheimer's and Parkinson's? Absolutely once the genetic coding associated with neuronal degeneration has been unraveled.

According to a new study published in The Journal of Neuroscience, a research team from the Universit de Montral, Maisonneuve-Rosemont Hospital and Lawrence Berkeley National Laboratory has taken a giant step in this direction by identifying a gene that controls the normal and pathological aging of neurons in the central nervous system: Bmi1.

The primary risk factor for diseases such as macular degeneration, Parkinson's and Alzheimer's is age. Although many researchers have sought to better understand the genetics and pathophysiology of these diseases, few studies have focused on the basic molecular mechanisms that control neuronal aging.

Dr. Gilbert Bernier, of the Universit de Montral and Maisonneuve-Rosemont Hospital, led a team that identified a mutation in mice that dramatically accelerates the process of aging in the brain and the eye. The new study reveals that neurons in the retina and cerebral cortex require a gene called Bmi1 to prevent activation of the p53 pathway and the accumulation of free radicals.

"Overall, we have now established that the Bmi1 gene is a direct regulator of cell aging in brain and retinal neurons of mammals through its action on the defense mechanisms against free radicals," says Dr. Bernier.


'/>"/>

Contact: Pascal Mailhot
pmailhot.hmr@ssss.gouv.qc.ca
514-252-3451
University of Montreal
Source:Eurekalert

Page: 1

Related medicine news :

1. University of Ottawa Heart Institute Scientists Successfully Develop Novel Biomaterial to Help Grow New Blood Vessels
2. Scientists develop new tool to improve oral hygiene
3. Scientists call up stem cell troops to repair the body using new drug combinations
4. Scientists identify new congenital neutropenia syndrome and causative gene mutation
5. Hebrew University scientists succeed through stem cell therapy in reversing brain birth defects
6. Scientists May Isolate Stem Cells From Rats, Other Mammals
7. Scientists Create New Means to Study Disease Origins
8. Scientists reveal structure of new botulism nerve toxin subtype
9. Scientists Discover Trigger for Autoimmune Diseases
10. Scientists Spot Key to Cystic Fibrosis Infections
11. Scientists, Physicians, Health, and Environmental Justice Advocates to New Obama EPA Director: We Look Forward to Toxic Chemical Regulatory Reform
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/23/2017)... , ... June 23, 2017 , ... ... Private Flood Insurance offerings. With the Federal Emergency Management Agency’s (FEMA) recent update ... the United States. In 2012, the Biggert-Waters Act was enacted to reflect the ...
(Date:6/23/2017)... (PRWEB) , ... June 23, 2017 , ... Ulster University, ... June, 2017 from 9 am to 3 pm to present to graduate students exciting ... is an original curriculum project led by The Health Improvement Service of the ...
(Date:6/23/2017)... ... June 23, 2017 , ... Jusino Insurance Services, ... communities in the greater Chicago metropolitan area, is embarking on a charity drive ... in Chicago. , Founded in 1897, Hephzibah Children’s Association is one of the ...
(Date:6/23/2017)... ... 23, 2017 , ... Radabaugh & Associates, a locally owned ... owners in North Central West Virginia, is embarking on a cooperative charity drive ... in the region. , The Stepping Stones organization offers a series of personal ...
(Date:6/22/2017)... ... 22, 2017 , ... Branches, Inc. has been partnering with The Miami Foundation ... support its programs focused on providing opportunity to low-income families and breaking the cycle ... Foundation of $15,000 to support its , Climb to College & Career initiative which ...
Breaking Medicine News(10 mins):
(Date:6/16/2017)... Datascope Corp. is voluntarily performing a worldwide field correction of ... test failure code.     ... PART NUMBER ... 0998-UC-0446HXX; 0998-UC-0479HXX 0998-00-3013-XX;  0998-UC-3013-XX ... This field correction also applies to ...
(Date:6/13/2017)... Zimmer Biomet Holdings, Inc. (NYSE and SIX: ZBH), ... U.S. Food and Drug Administration (FDA) has notified the Company ... its Zhejiang, China manufacturing facility has ... successful clearance of the Warning Letter related to our ... measure of the progress we have made in our ongoing ...
(Date:6/9/2017)... INDIANAPOLIS , June 9, 2017 More ... a further effort to help spread lessons learned from ... the International Diabetes Federation (IDF) and Eli Lilly and ... for the second phase of the Bringing Research in ... reaffirming their commitment to helping people with diabetes effectively ...
Breaking Medicine Technology: