Navigation Links
Can hormone help treat multiple sclerosis long-term?
Date:3/10/2013

SAN DIEGO A new study suggests that treatment with adrenocorticotropic hormone (ACTH) may be helpful for people whose multiple sclerosis (MS) is not well-controlled through their regular treatment. The study was released today and will be presented at the American Academy of Neurology's 65th Annual Meeting in San Diego, March 16 to 23, 2013.

The study involved 23 people with MS who were taking beta-interferon treatment and had at least one relapse or brain scan showing new disease activity within the previous year. They were considered to have "breakthrough" MS, which means that their treatment that had been working previously stopped being effective, leading to worsening disability and more frequent relapses, as well as increased evidence of disease activity on brain scans.

The study participants were given either ACTH or methylprednisolone as pulse therapy monthly in addition to their regular treatment for one year. The people with MS knew which treatment they were receiving, but the researchers examining them did not.

The participants were tested every three months for 15 months. Over that time, those receiving ACTH had fewer relapses, or 0.08 cumulative relapses per patient compared to 0.8 relapses per patient for those receiving methylprednisolone. Those taking ACTH also had no cases of psychiatric side effects, while those taking methylprednisolone had a cumulative number of 0.55 psychiatric episodes per patient.

"These results are of interest because few treatments are available for people with breakthrough MS," said study author Regina Berkovich, MD, PhD, of Keck Medical Center of USC in Los Angeles. "Further studies, including randomized controlled trials, are needed to validate these preliminary findings, but the results suggest a potential benefit of ACTH pulse therapy in breakthrough MS."

While ACTH has been approved for use in MS relapses for many years, its cost has limited its use to only those pati
'/>"/>

Contact: Rachel Seroka
rseroka@aan.com
612-928-6129
American Academy of Neurology
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Procedure Lowers Hunger Hormone to Help Obese Lose Weight
2. Stress hormone foreshadows postpartum depression in new mothers
3. Thyroid hormones reduce damage and improve heart function after myocardial infarction in rats
4. Renew Health and Wellness, a Hormone Replacement and Weight Loss Clinic Based in St. Louis, MO, Announces the Addition of Tara Smith, NP, to Their Staff of Professionals
5. Could Duration of Prostate Cancer Hormone Therapy Be Halved?
6. Anti-Muellerian hormone predicts IVF success
7. Study finds hormones can change the breasts genetic material
8. Test for hormone-disrupting chemicals gets global seal of approval
9. Love Hormone May Aid Womens Recovery After Childbirth
10. New hormone therapy shows promise for menopausal symptoms in animal model
11. Hormone Replacement Clinic, Renew Health and Wellness Opens in Richmond, Virginia. New Center Specializes in Anti-Aging Therapies for both Women and Men.
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/22/2014)... Steven Reinberg HealthDay Reporter ... that break up blood clots deep in the veins of ... However, one results in a greater risk of bleeding and ... the other treatment, a new study finds. The standard ... (DVT) -- is blood-thinning medications and compression stockings. The other, ...
(Date:7/22/2014)... undergoing a minimally invasive hysterectomy using electric power morcellation, ... at the time of the procedure, according to a ... concern that this procedure, in which the uterus is ... of undetected malignancies. , Despite the commercial availability of ... the prevalence of malignancy at the time of electric ...
(Date:7/22/2014)... The American Society of Hematology (ASH) will present the ... for Lifetime Achievement in Hematology, to Kanti R. Rai, ... School of Medicine for his 50-year career combining landmark ... and exceptional patient care. , The Wallace H. ... on an individual who has been a vital contributor ...
(Date:7/22/2014)... mechanisms with cancer, according to a new report by ... , published in PLOS ONE on July ... very same inhibitors of apoptosis, or cell destruction, in ... diseases. Henry Kaminski, M.D. , chair of the ... and Health Sciences (SMHS), as well as colleagues from ...
(Date:7/22/2014)... Ticket Down is a reliable source ... Fedex Field in Landover, MD. There has never been a ... international soccer. After the success of the American national soccer team ... and well. One way that fans of the world’s sport will ... the 2014 Guinness International Champions Cup. The tournament will kick off ...
Breaking Medicine News(10 mins):Health News:Study Casts Doubt on Costly Treatment for Leg Clots 2Health News:Study Casts Doubt on Costly Treatment for Leg Clots 3Health News:Study examines presence of uterine cancers at the time of hysterectomy using morcellation 2Health News:ASH honors Kanti R. Rai, M.D., with Coulter Award for Lifetime Achievement 2Health News:ASH honors Kanti R. Rai, M.D., with Coulter Award for Lifetime Achievement 3Health News:ASH honors Kanti R. Rai, M.D., with Coulter Award for Lifetime Achievement 4Health News:New research finds pathogenic connection between autoimmune disorders and cancer 2Health News:Manchester United vs. Inter Milan Tickets Fedex Field Landover: Ticket Down Slashes Ticket Prices for Inter Milan ManU International Champions Cup Match in Washington, DC 2Health News:Manchester United vs. Inter Milan Tickets Fedex Field Landover: Ticket Down Slashes Ticket Prices for Inter Milan ManU International Champions Cup Match in Washington, DC 3
... of patients whose myelodysplastic syndrome is related to earlier ... have a poor prognosis, researchers from The University of ... Annual Meeting of the American Society of Hematology. ... or both treatments are usually told that they have ...
... of biological macromolecules are the central bases of ... cells by linking many small molecules together. Naturally ... A detailed understanding of the synthesis of these ... for understanding biological systems, and for the development ...
... smells apart is no problem for the human nose. How ... by an interdisciplinary team of researchers at the RUB. The ... of the three-dimensional structure of the binding site of an ... pattern of hydrogen bonds between odorant and receptor, which accounts ...
... News) -- Undiagnosed chronic fatigue syndrome may account for up ... for extended periods of time and are not truant or ... out of school, a new study reveals. For the ... 16 at three secondary schools in England and concluded that ...
... US Prostate Cancer Prevention Trial found cancer in many men ... which PSA level should lead to a biopsy recommendation. ... considerable controversy, that the evidence does not support recommending PSA ... the risks outweigh the benefits. Now, a study shows ...
... - Adding a drug that activates genes to frontline combination ... remission rate after initial treatment, researchers at The University of ... Meeting of the American Society of Hematology. Results of ... stage for a national Phase III clinical trial of the ...
Cached Medicine News:Health News:Prognostic model developed for MDS related to prior cancer therapy 2Health News:Prognostic model developed for MDS related to prior cancer therapy 3Health News:Visualization of DNA synthesis in vivo 2Health News:A good nose: RUB-Researchers decipher interaction of fragrances and olfactory receptors 2Health News:Chronic Fatigue Tied to Extended School Absences 2Health News:Biopsy referral after PSA screening stays consistent over time 2Health News:AML patients have high response rate with vorinostat added to treatment 2
(Date:7/22/2014)... PLANTATION, Fla. , July 22, 2014  Neurotrope ... has signed a world-wide, exclusive license agreement with the ... ( Mount Sinai ) to ... use of Bryostatin-1 in the treatment of Niemann-Pick Type ... who are afflicted with Alzheimer-like symptoms. The license also ...
(Date:7/22/2014)... , July 22, 2014  According to the ... their children spend on digital devices. An AOA survey ... of 10 and 17 estimate they use an electronic ... a separate AOA survey of parents revealed that only ... electronic device for that same amount of time. Eye ...
(Date:7/22/2014)... MARCOS, Texas , July 22, 2014 Quantum Materials ... and Mr. John Heaton to the Board of ... by Dr. Ghassan Jabbour , QMC Chief Science Officer and ... Michael Wong of Rice University and Mr. Tomio ... Japan . " Quantum Materials welcomes ...
Breaking Medicine Technology:Neurotrope Enters Collaborative Agreement with Icahn School of Medicine at Mount Sinai for use of Bryostatin-1 in the Treatment of Niemann-Pick Disease Type C 2Neurotrope Enters Collaborative Agreement with Icahn School of Medicine at Mount Sinai for use of Bryostatin-1 in the Treatment of Niemann-Pick Disease Type C 3Neurotrope Enters Collaborative Agreement with Icahn School of Medicine at Mount Sinai for use of Bryostatin-1 in the Treatment of Niemann-Pick Disease Type C 4Neurotrope Enters Collaborative Agreement with Icahn School of Medicine at Mount Sinai for use of Bryostatin-1 in the Treatment of Niemann-Pick Disease Type C 5Survey Reveals Parents Drastically Underestimate the Time Kids Spend on Electronic Devices 2Survey Reveals Parents Drastically Underestimate the Time Kids Spend on Electronic Devices 3Survey Reveals Parents Drastically Underestimate the Time Kids Spend on Electronic Devices 4Quantum Materials Announces New Outside Directors and Adds Scientific Advisory Board 2Quantum Materials Announces New Outside Directors and Adds Scientific Advisory Board 3Quantum Materials Announces New Outside Directors and Adds Scientific Advisory Board 4
... Jan. 3, 2012  theVisualMD, www.thevisualmd.com , the world,s leading ... initiative, The 9 Visual Rules of Wellness. Quest Diagnostics (NYSE: ... testing, information and services, is the official sponsor of the ... 9 Visual Rules of Wellness aim to bring readers a ...
...  Arena Pharmaceuticals, Inc. (NASDAQ: ARNA ) and Eisai ... the Complete Response Letter (CRL) issued by the US Food ... Drug Application (NDA). Lorcaserin is intended for weight management, including ... are obese (Body Mass Index, or BMI, >30) or patients ...
Cached Medicine Technology:theVisualMD Launches a Revolutionary New Visual Path to Wellness 2theVisualMD Launches a Revolutionary New Visual Path to Wellness 3theVisualMD Launches a Revolutionary New Visual Path to Wellness 4Arena Submits Response to FDA Complete Response Letter for Lorcaserin 2Arena Submits Response to FDA Complete Response Letter for Lorcaserin 3Arena Submits Response to FDA Complete Response Letter for Lorcaserin 4Arena Submits Response to FDA Complete Response Letter for Lorcaserin 5Arena Submits Response to FDA Complete Response Letter for Lorcaserin 6
... Flowmaster. It is a new portable digital flowmeter ... of use, simplicity and cost effectiveness are top ... now very easy to give a patient some ... and data will be send wirelessly to the ...
... the second generation of Urocap, ... zeroing, starting, stopping and printing. ... uroflowmetry parameters with superior low ... provides standard ICS nomenclature normative ...
... Uro-Guide Open Tip Ureteral ... silicone over-the-wire stents and ... design with an open ... of time-tested biocompatible silicone ...
... patient position during surgery is key to ... procedures. Not every patient is able to ... movements can compromise the procedure or necessitate ... Rousseau chin-lift stabilizer eliminates the "drifting that ...
Medicine Products: