Navigation Links
Can eGFR be a routine preoperative renal function test?
Date:5/20/2010

The creatinine clearance (Ccr) test has been used as a gold standard for evaluation of preoperative renal function in patients with gastric cancer. However, it is known that Ccr is not strictly equivalent to glomerular filtration rate (GFR). It has been accepted that estimated GFR (eGFR) is equal to measured GFR in chronic kidney disease. However, there have been no studies regarding the reliability of eGFR as a preoperative renal function test in gastric cancer patients.

A research article to be published on May 21, 2010 in the World Journal of Gastroenterology addresses this question. The research team from Second Department of Surgery, Dokkyo Medical University, Japan, analyzed Ccr and eGFR retrospectively in a series of gastric cancer patients.

Among 110 patients with normal preoperative Ccr values, 7 (6.3%) had abnormal postoperative sCr values, and among 112 patients with normal preoperative eGFR values, postoperative sCr was abnormal in 5 (4.5%). Among 37 patients with abnormal preoperative Ccr values, 30 (81.1%) had normal postoperative sCr values, and of 35 patients with abnormal preoperative eGFR values, postoperative sCr was normal in 25 (71.4%). Preoperative Ccr was significantly correlated with eGFR, and postoperative sCr was significantly correlated with preoperative Ccr and eGFR.

The authors concluded that eGFR is as equally valuable as Ccr as an indicator of preoperative renal function in patients with gastric cancer, and that eGFR may now be used in place of Ccr in view of the former's clear medical and socioeconomic advantages.


'/>"/>

Contact: Ye-Ru Wang
wjg@wjgnet.com
86-105-908-0039
World Journal of Gastroenterology
Source:Eurekalert

Page: 1

Related medicine news :

1. AIDS Drugs Dont Need Routine Lab Monitoring
2. Siemens Boosts Advanced Image Reading Efficiency and Opens New Path Into The Clinical Routine with syngo(R).via
3. MRI May Not Add Value to Routine Breast Cancer Care
4. Is Your Exercise Routine Killing You?
5. Flexible Floor-Cleaning Routine Helps School Prevent Spread of Infection
6. Maintaining regular daily routines is associated with better sleep quality in older adults
7. Routine screening for pediatric chronic kidney disease is not effective
8. New U of A research goes against moms advice that routine lifting is bad for your back
9. Routine breast cancer biopsy might predict lymph node cancer spread
10. Study: Carbon Monoxide Exposure Can be Reduced During Routine Anesthesia in Kids
11. New commentary suggests alternatives to routine use of OTC cold/cough meds in children
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/24/2017)... ... , ... As a former supermodel known for her timeless beauty, Joan Severance ... women is that she put all the words in her new book, "Manifest Your ... experiences and sparkling sense of humor have inspired her to write a book on ...
(Date:4/24/2017)... ... , ... “Reflections of God’s Work”: an enlightening collection of life lessons leading ... of published author, Jerri Broglin, a survivor of great loss who gained insight on ... eye-opener for those searching for answers, as we are finding the answers that are ...
(Date:4/24/2017)... (PRWEB) , ... April 24, 2017 , ... ... lifestyle brands, work wear distributors and International relief organizations across the globe to ... company also offers lifestyle and work wear collections via insectshield.com . In ...
(Date:4/22/2017)... ... April 22, 2017 , ... Ecommerce sales have grown every year since the ... billion. The consequences of rapid innovation and growth are often neglected in the ... is every business and individual’s job to give something back to the planet that ...
(Date:4/21/2017)... ... 21, 2017 , ... An April 10 article in the Daily ... reveal a great deal about prehistoric ice-age dental practitioners and their primitive and, no ... to remove decayed dental matter, and that teeth were then filled with bitumen, a ...
Breaking Medicine News(10 mins):
(Date:4/19/2017)... SAN DIEGO , April 19, 2017 /PRNewswire/ ... ("Sorrento"), an antibody-centric, clinical-stage biopharmaceutical company developing new ... today announced the closing of its previously announced ... common stock at a public offering price of ... commissions and estimated offering expenses payable by Sorrento.  ...
(Date:4/19/2017)... EAST HANOVER, N.J. , April 19, 2017 ... study conducted by the National Heart, Lung, and ... Health (NIH) demonstrating that 58% of patients with ... at six months when treated with eltrombopag at ... treatment 1 . The study evaluated three sequential ...
(Date:4/18/2017)... , April 18, 2017 Cogentix Medical, ... on providing the Urology, Uro/Gyn and Gynecology markets with ... the first quarter ended March 31, 2017 after the ... The Company will host a conference call and ... on Tuesday, May 2, 2017 at 4:30 p.m. Eastern ...
Breaking Medicine Technology: