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Can disclosure hurt the translation of research?
Date:9/19/2012

d to an even greater extent when compared with the same trials characterized as having NIH funding. The authors attributed these results to high-profile instances of unethical behavior by pharmaceutical companies sponsoring clinical research in the past decade.

Researchers emphasize that these findings have important implications. The pharmaceutical industry funds a substantial portion of clinical research, and a key determinant of the impact of a trial should be its methodological rigor, not its funding source, Dr. Kesselheim and his co-authors argue.

"While there is good reason to be extra vigilant about industry-funded research, if physicians are reluctant to trust all such research, this could hinder the translation of even high-quality industry-funded research into practice. Strategies such as greater transparency and independent review of trial data could be pursued to try to change such attitudes among physicians," Dr. Kesselheim suggested.


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Contact: Jessica Maki
jmaki3@partners.org
617-534-1603
Brigham and Women's Hospital
Source:Eurekalert

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