Navigation Links
Can charcoal fight heart disease in kidney patients?

Charcoal may provide a new approach to managing the high rate of heart disease in patients with advanced kidney disease, according to preliminary research being presented at the American Society of Nephrology's 42nd Annual Meeting and Scientific Exposition in San Diego, CA.

Patients with advanced kidney disease have high rates of atherosclerosis ("hardening of the arteries") and death from heart disease. Oral activated charcoala product called AST-120has traditionally been used as an emergency treatment for certain types of poisoning. Recent studies have suggested that AST-120 may exert beneficial effects in kidney disease.

"We found that oral activated charcoal lessens atherosclerotic lesions in experimental mice with kidney damage," comments Valentina Kon, MD (Vanderbilt University). "This is especially important because there is no effective treatment to reduce the high rate of cardiovascular mortality in patients with end-stage renal disease."

The researchers studied the effects of AST-120 in mice genetically engineered to develop atherosclerosis. The effects were assessed in mice with different levels of kidney mass.

In mice with profoundly reduced renal mass, treatment with AST-120 led to a dramatic decrease in atherosclerosis. This was so even when charcoal treatment was delayed. The improvement in atherosclerosis was unrelated to changes in blood pressure or cholesterol levels. Rather, the effect appeared related to reduced inflammation in the blood vessels.

In mice, oral activated charcoal appears to reduce atherosclerosis associated with kidney disease. The effect is present at different levels of kidney function, in very advanced atherosclerosis, and even when treatment is delayed. More research is needed to see if AST-120 offers similar benefits in humans with kidney disease.


Contact: Shari Leventhal
American Society of Nephrology

Page: 1

Related medicine news :

1. Brown & Toland Supports Fight Against Hepatitis B
2. Company C Donates $40,000 To Fight Breast Cancer
3. Minnesota Charity Launches Global Initiative to Help Children and Families Fighting Chronic Illnesses
4. Let Kids Sleep Late on Weekends to Fight Fat: Study
5. Physical scientists at Arizona State University will apply laws of physics in cancer fight
6. Lifestyle Changes Remain Important in Fighting Peripheral Arterial Disease (PAD)
7. New Quick and Convenient Emergen-C(R) Shot Gives Immune Systems a Fighting Chance This Fall
8. Bill & Melinda Gates Foundation Rewards 76 New Ideas to Fight Infectious Disease
9. Kimberly-Clark Professional Announces Clean Hands Campaign and Flu Fighters Contest To Help Protect Office Workers From Flu
10. Sams Day Celebrates 5 Year Anniversary; Local Family Event Will Benefit Largest U.S. Non-Profit Fighting Duchenne Muscular Dystrophy
11. Mars Lends Sweet Support in Fight Against Breast Cancer Through Its M&Ms(R) And Dove(R) Chocolate Brands, as Well as Its Celebrated Race Team
Post Your Comments:
(Date:6/25/2016)... ... June 25, 2016 , ... "With 30 hand-drawn hand gesture animations, FCPX ... Austin - CEO of Pixel Film Studios. , ProHand Cartoon’s package transforms over ... Cut Pro X . Simply select a ProHand generator and drag it above media ...
(Date:6/25/2016)... ... June 25, 2016 , ... As a lifelong Southern Californian, Dr. Omkar ... M.D from the David Geffen School of Medicine at UCLA. He trained in Internal ... complete his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program where he had ...
(Date:6/25/2016)... ... June 25, 2016 , ... On Friday, June 10, ... Bronze Wellness at Work award to iHire in recognition of their exemplary accomplishments in ... the 7th annual Maryland Workplace Health & Wellness Symposium at the BWI Marriott in ...
(Date:6/24/2016)... ... June 24, 2016 , ... A recent article ... people are unfamiliar with. The article goes on to state that individuals are now ... of these less common operations such as calf and cheek reduction. The Los Angeles ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... June 19, ... the dangers associated with chronic pain and the benefits of holistic treatments, Serenity ... who are suffering with Sickle Cell Disease. , Sickle Cell Disease (SCD) is a ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 Revolutionary ... Oticon , industry leaders in advanced audiology ... of Oticon Opn ™, the world,s first internet ... possibilities for IoT devices.      (Photo: ... introduces a number of ,world firsts,: , ...
(Date:6/23/2016)... MEDIA, Pa. , June 23, 2016 ... treatments in an outpatient dialysis facility.  Treatments are usually ... to 6 hours per visit, including travel time, equipment ... on a patient, but especially grueling for patients who ... residents of a skilled nursing and rehabilitation centers for ...
(Date:6/23/2016)... June 23, 2016  Experian Health, the ... transforming the patient payment and care experience, ... new products and services that will enhance ... cycle offerings. These award-winning solutions will enable ... remain compliant in an ever-changing environment and ...
Breaking Medicine Technology: