Navigation Links
Can charcoal fight heart disease in kidney patients?
Date:10/31/2009

Charcoal may provide a new approach to managing the high rate of heart disease in patients with advanced kidney disease, according to preliminary research being presented at the American Society of Nephrology's 42nd Annual Meeting and Scientific Exposition in San Diego, CA.

Patients with advanced kidney disease have high rates of atherosclerosis ("hardening of the arteries") and death from heart disease. Oral activated charcoala product called AST-120has traditionally been used as an emergency treatment for certain types of poisoning. Recent studies have suggested that AST-120 may exert beneficial effects in kidney disease.

"We found that oral activated charcoal lessens atherosclerotic lesions in experimental mice with kidney damage," comments Valentina Kon, MD (Vanderbilt University). "This is especially important because there is no effective treatment to reduce the high rate of cardiovascular mortality in patients with end-stage renal disease."

The researchers studied the effects of AST-120 in mice genetically engineered to develop atherosclerosis. The effects were assessed in mice with different levels of kidney mass.

In mice with profoundly reduced renal mass, treatment with AST-120 led to a dramatic decrease in atherosclerosis. This was so even when charcoal treatment was delayed. The improvement in atherosclerosis was unrelated to changes in blood pressure or cholesterol levels. Rather, the effect appeared related to reduced inflammation in the blood vessels.

In mice, oral activated charcoal appears to reduce atherosclerosis associated with kidney disease. The effect is present at different levels of kidney function, in very advanced atherosclerosis, and even when treatment is delayed. More research is needed to see if AST-120 offers similar benefits in humans with kidney disease.


'/>"/>

Contact: Shari Leventhal
sleventhal@asn-online.org
202-558-8423
American Society of Nephrology
Source:Eurekalert

Page: 1

Related medicine news :

1. Brown & Toland Supports Fight Against Hepatitis B
2. Company C Donates $40,000 To Fight Breast Cancer
3. Minnesota Charity Launches Global Initiative to Help Children and Families Fighting Chronic Illnesses
4. Let Kids Sleep Late on Weekends to Fight Fat: Study
5. Physical scientists at Arizona State University will apply laws of physics in cancer fight
6. Lifestyle Changes Remain Important in Fighting Peripheral Arterial Disease (PAD)
7. New Quick and Convenient Emergen-C(R) Shot Gives Immune Systems a Fighting Chance This Fall
8. Bill & Melinda Gates Foundation Rewards 76 New Ideas to Fight Infectious Disease
9. Kimberly-Clark Professional Announces Clean Hands Campaign and Flu Fighters Contest To Help Protect Office Workers From Flu
10. Sams Day Celebrates 5 Year Anniversary; Local Family Event Will Benefit Largest U.S. Non-Profit Fighting Duchenne Muscular Dystrophy
11. Mars Lends Sweet Support in Fight Against Breast Cancer Through Its M&Ms(R) And Dove(R) Chocolate Brands, as Well as Its Celebrated Race Team
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/22/2017)... ... September 22, 2017 , ... Silicon Valley ... even on the go. Their electric toothbrushes aggressively attack oral bacteria by reducing ... sanitizing technology. Combining leading edge Enke technology with a premium timeless design, they ...
(Date:9/22/2017)... ... September 22, 2017 , ... “Letters From Home”: a moving ... lost, have value to God. “Letters From Home” is the creation of published author, ... the President’s Cabinet of Jerry Savelle Ministries International, who has traveled and ministered on ...
(Date:9/22/2017)... ... September 22, 2017 , ... ... and create life. Although frozen embryos have a slight statistical advantage for live ... freezing is a wonderful opportunity for women undergoing medical treatment or who are ...
(Date:9/21/2017)... ... 21, 2017 , ... With ProSlideshow Portrait from Pixel Film Studios creating a ... select from up to two layers of subject matter along with fully customizable backdrop ... Final Cut Pro X. , With ProSlideshow Portrait each user are given ...
(Date:9/21/2017)... ... 21, 2017 , ... Process Capability Indices for Medical Device ... ET, http://www.fdanews.com/processcapabilityindices      , Quality in device manufacturing is ... Quality System Regulation (§820.250), and Devicemakers find themselves staring at a warning letter. ...
Breaking Medicine News(10 mins):
(Date:9/9/2017)... ... ... – Monday, September 18 th .The Brain Tumor Foundation (BTF) begins ... the public.Where:  BTF,s Mobile MRI Unit – a ... Washington, D.C.What:BTF brings its nationwide initiative, the Road to Early Detection Sponsor-A-City ...
(Date:9/9/2017)... Lilly and Company (NYSE: LLY ) will ... an investigational, oral, first-in-class molecule for the acute treatment ... placebo in the Phase 3 SPARTAN study. Detailed results ... the International Headache Society (IHC) in Vancouver ... lasmiditan,s potential to reduce pain and provide freedom from ...
(Date:9/7/2017)... MIRAGE, Calif. , Sept. 7, 2017  For nearly two decades, ... service in the Assisted Reproduction Insurance industry. Today, New Life Agency announces ... fertility medications. ... http://pharmacarecard.com/ (PRNewsfoto/PharmaCareCard) ... ...
Breaking Medicine Technology: