Navigation Links
Can aspirin prolong a healthy life?
Date:7/7/2010

WINSTON-SALEM, N.C. Wednesday, July 7, 2010 In an effort to extend the length of a disability-free life for older adults, researchers from Wake Forest University Baptist Medical Center are partnering with colleagues from across the US and Australia in the largest international trial ever sponsored by the US National Institute on Aging (NIA).

The Aspirin in Reducing Events in the Elderly (ASPREE) study aims to assess whether aspirin can not only prolong life, but a life free of physical disability and/or dementia for healthy older people.

According to Jamehl Demons, M.D., an assistant professor of geriatric medicine and an ASPREE investigator from Wake Forest Baptist, "We have, through technology, been able to prolong life but not necessarily function in our seniors. This study will allow us to look at a possible mechanism for maintaining functional independence. The population of age 70+ is such a vulnerable one for functional decline; this is the perfect group to target for interventions such as aspirin."

While it is known that aspirin prevents heart attacks and strokes in people with established heart disease benefits which clearly outweigh any risks associated with aspirin, such as bleeding the role of aspirin in people without a history of cardiovascular disease is less certain.

"In the US, Australia and elsewhere, people are living longer so identifying treatments to prolong life free of physical disability and memory problems is increasingly important," said ASPREE investigator Anne Murray, M.D., MSc, an epidemiologist and geriatrician, and associate professor of medicine and geriatrics at the University of Minnesota. "Aspirin is a potentially useful drug as it is cheap and widely available."

To date, very little information is available about the overall effects of aspirin in older adults, because most trials focus on middle-aged people. The ASPREE study, for the first time, will determine whether the potential benefits of low dose aspirin outweigh the risks specifically for people age 70 and older.

"Because of its proven effectiveness in preventing second events, many doctors have also prescribed aspirin to prevent heart attacks and strokes in otherwise healthy people," said Professor John McNeil, Head of the Monash School of Public Health and Preventative Medicine in Australia, and also a principal investigator for ASPREE. "However, in the last couple of years, serious doubts have been raised about the evidence supporting this practice, and as a result, editorials in major medical journals have called for this question to be settled."

The ASPREE study will enroll 6,500 healthy individuals age 70 and over in the US and another 12,500 in Australia. Two hundred of those participants will be local from the Triad area. All eligible participants will be randomly assigned to take either low dose aspirin or placebo daily for about 5 years.

Patients will receive initial measurements on specific health markers, as well as functional and cognitive ability, and changes in these will be monitored throughout the study.

"The magnitude of this study will mean we will be able to answer a question looming in minds of physicians and patients for quite some time: how to remain mentally and physically independent as we age," Demons said.


'/>"/>

Contact: Jessica Guenzel
jguenzel@wfubmc.edu
336-716-3487
Wake Forest University Baptist Medical Center
Source:Eurekalert

Related medicine news :

1. Aspirin May Boost Breast Cancer Survival
2. Cardiologists Comment on Aspirin Versus Resveratrol
3. Aspirin Alone Works Best to Prevent Clots a Year After Stenting
4. Aspirin May Increase Risk of Crohns Disease
5. Experts Advise At-Risk Diabetics to Begin Daily Aspirin Later
6. Aspirin recommendations changed for many younger diabetic patients
7. Kidney removal does not prolong the lives of elderly patients with localized kidney cancer
8. New treatment approach to rare cancer results in prolonged survival
9. Say “I Love You” From Head to Toe with a Gift That's Healthy and Soothes Away Stress this Valentine's Day
10. PERSONALABS Offers Discounted Healthy Heart Online Blood Tests in February
11. Cigars, Pipes No Healthy Alternative to Cigarettes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/8/2016)... ... 2016 , ... Stephanie Hebert Insurance Agency, serving families of ... charity campaign. As part of their ongoing community involvement program, funds are now ... children deserve a voice, and in the spirit of neighbors helping neighbors in ...
(Date:2/8/2016)... , ... February 08, 2016 , ... A man who has struggled to quit smoking, ... Laser Therapy , was determined to find solutions to his problems – and he did. ... Digest is ready to introduce his breakthrough inventions to the world and better people's ...
(Date:2/8/2016)... York, NY (PRWEB) , ... February 08, 2016 , ... ... are too much to handle, you are not alone. According to the Center for ... include heart disease, stroke, type 2 diabetes and certain types of cancer, some of ...
(Date:2/8/2016)... Hilton Head Island, SC (PRWEB) , ... February 08, 2016 , ... ... Head and surrounding areas with a vital new community enrichment program, has teamed up ... to local women and children suffering from intimate abuse. To support all those victimized ...
(Date:2/8/2016)... ... February 08, 2016 , ... Local ... the greater Venice, FL area, has initiated a fundraiser for a two year ... just four days after Christmas. To support this beautiful child who is facing ...
Breaking Medicine News(10 mins):
(Date:2/8/2016)... Cardiovascular Surgery Devices - Medical Devices Pipeline Assessment, ... report, "Cardiovascular Surgery Devices - Medical Devices Pipeline ... Devices currently in pipeline stage. ... comprehensive information on the pipeline products with comparative ... development. The report reviews major players involved in ...
(Date:2/8/2016)... 2016  Labvantage Lx, a newcomer to the ... sexual enhancement product, EnduramenT. Setting a new standard ... a patented biomedical breakthrough molecule that promotes the ... responsible for many biological functions including erectile function. ... Forgoing the use of prescription medications, scientists working ...
(Date:2/8/2016)... TOKYO and FAIRFIELD, N.J. ... (Otsuka) and Medimetriks Pharmaceuticals, Inc. (Medimetriks) today announced that ... exclusive development and commercialization rights for OPA-15406 in the ... agreement also provides manufacturing rights.  OPA-15406 is a topical, ... for atopic dermatitis. --> ...
Breaking Medicine Technology: