Navigation Links
Can a Contact Lens Cure Nearsightedness? Five-Year Clinical Study Testing Corneal Reshaping Therapy as Possible Method to Arrest Myopia
Date:7/7/2009

Researchers have reported positive first-year results from a clinical trial that is testing whether specialized contact lenses can slow or halt the progression of near sightedness in children. Co principal investigators Drs S. Barry Eiden and Robert Davis, working with EyeVis Eye and Vision Research Institute, recently reported on initial results from the SMART Trial (Stabilization of Myopia by Accelerated Reshaping Technique).

Chicago (PRWEB) July 7, 2009 -- Researchers have reported positive first-year results from a clinical trial that is testing whether specialized contact lenses can slow or halt the progression of near sightedness in children.

Co principal investigators Drs S. Barry Eiden and Robert Davis, working with EyeVis Eye and Vision Research Institute, recently reported on initial results from the SMART Trial (Stabilization of Myopia by Accelerated Reshaping Technique).

The clinical study, which has 10 investigational sights located throughout the United States, has enrolled approximately 300 subjects aged 8 to 14 to determine if wearing corneal reshaping contact lenses on an overnight basis stops or slows the progression of myopia (nearsightedness) in children.

Overnight corneal reshaping (also termed overnight orthokeratology, corneal refractive therapy, and vision shaping treatment) is a non-surgical process that utilizes specially designed contact lenses to change the shape of the cornea. Lenses are worn overnight during sleep only. Once removed upon waking the induced flatter curvature of the cornea results in clear vision thus reducing or eliminating the dependence on contact lenses or glasses during waking hours.

Approximately 25 percent of the U.S. population has myopia while the incidence of nearsightedness approaches 70 percent in some Asian countries. High levels of myopia are associated with a number of risk factors for permanent vision loss and also effects vision performance that can have deleterious influences on a child's school and sports performance. This makes a treatment that may control myopia progression very significant.

"Correcting and controlling nearsightedness is very important because it potentially contributes to eye disease conditions and problems in academic and social activities, " said Dr. S. Barry Eiden, co principal investigator of the SMART Study, and president of North Suburban Vision Consultants, Deerfield, Ill., one of the clinic sites in the five-year, SMART trial.

The FDA approved corneal reshaping therapy in 2002 to treat myopia. However, as more eye care professionals and patients used CRT, anecdotal information emerged that suggested CRT could not only correct myopia but it could slow the progression of the disorder compared to normal contact lenses or eyeglasses. Two small-scale studies in Hong Kong and at the Ohio State University support this conclusion and a new, multi-site trial (the SMART Study) began in 2007 involving hundreds of U.S. teens and pre-teens.

A year ago, U.S. investigators started their own study of nearsighted children and teens to test whether the anecdotal information was accurate. In the SMART study, half of the subjects are fitted with Boston Equalens II gas permeable contact lens polymer in a reverse geometry/corneal reshaping lens design. The control group subjects are fitted with normal soft contact lenses worn on a daily wear basis.
"The net effect of this contact lens fitting philosophy is to change the cornea shape for the sole purpose of reducing the amount of myopia as measured by change in refraction," said Dr. Robert L. Davis, of Davis Eye Care Associates, Oak Lawn, Ill., co principal investigator of the SMART trial.

Each subject will be followed for five years and be seen by optometric and ophthalmologic researchers at staged intervals throughout each year for evaluation. Once annually investigators will collect the contact lenses and test the subject's vision to determine how far their myopia has progressed. The first-year data showed that the corneal reshaping lenses did control nearsightedness progression in comparison to the control soft lens subjects who became significantly more nearsighted than the test corneal reshaping lens subjects.

According to Dr. S. Barry Eiden the trial will also investigate why these special lenses may be effective in slowing myopia.

"Current thinking suggests that these CRT lenses flatten the cornea but other evidence suggests that these lenses may influence the growth in eyeball length (termed axial length). A major contributor to progressive nearsightedness is axial length elongation. Corneal reshaping may actually result in decreased axial length growth. The exact mechanism by which this happens is still being investigated" said Dr. Eiden.

"The results of the SMART Study so far are very exciting," said Dr. Davis. "The outcomes of this study may revolutionize how we manage young nearsighted patients from this point forward".

EyeVis and Eye and Vision Research Institute is the sponsor of the SMART Study through an unrestricted research grant from Bausch & Lomb and Euclid Technologies.

Visit the SMART Trial Facebook page to learn more: http://companies.to/smartclinicaltrial/

###

Read the full story at http://www.prweb.com/releases/2009/07/prweb2612144.htm.


'/>"/>
Source: PRWeb
Copyright©2009 Vocus, Inc.
All rights reserved

Related medicine news :

1. Amcat Partners With Gryphon to Provide Comprehensive and Guaranteed Do Not Call (DNC) Compliance Solution for Outbound Contact Activities
2. Service-to-Sales Transformation at Contact Centers Hinges on Soft Skills
3. Presentation at Bio Contact Quebec 2007
4. ILC Dover Launches Revolutionary ArmorFlex (R) Pharmaceutical Product Contact Film
5. ACUVUE(R) 2 COLOURS(R) Brand Contact Lenses Launches Virtual Eye Makeover Tool
6. Worlds First Non-Contact Thermometer for Children Now Available at Walgreens Nationwide
7. ECO2 Plastics to File for FDA Approval for Food-Contact Applications
8. Contact Lens Shift Can Compromise Vision of People with Astigmatism with the Blink of an Eye
9. Contact lenses purchased over Internet may place individuals at risk for harmful eyecare practices
10. Eye Care Lacking in Many Who Buy Contact Lenses Online
11. Contact lenses with circuits, lights a possible platform for superhuman vision
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... ... 27, 2016 , ... "FCPX editors can now reveal their media with growing ... said Christina Austin - CEO of Pixel Film Studios. , ProSlice Color brings ... users can now reveal the media of their split screens with growing colorful panels. ...
(Date:6/27/2016)... , ... June 27, 2016 , ... TopConsumerReviews.com recently awarded ... Eyeglasses . , Millions of individuals in the United States and Canada wear ... a way to both correct vision and make a fashion statement. Even celebrities use ...
(Date:6/26/2016)... ... ... PawPaws brand pet supplements owned by Whole Health Supply is ... of felines. The formula is all-natural and is made from Chinese herbs that have ... Kidney Support Supplement Soft Chews are Astragalus Root Extract and Rehmannia Root Extract ...
(Date:6/25/2016)... ... , ... Austin residents seeking Mohs surgery services, can now turn to Dr. ... Russell Peckham for medical and surgical dermatology. , Dr. Dorsey brings specialization to include ... in Mohs Micrographic Surgery completed by Dr. Dorsey was under the direction of Glenn ...
(Date:6/25/2016)... ... June 25, 2016 , ... As a lifelong Southern Californian, Dr. ... his M.D from the David Geffen School of Medicine at UCLA. He trained in ... to complete his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program where he ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 24, 2016 According to a ... (Standard Pen Needles, Safety Pen Needles), Needle Length (4mm, ... Hormone), Mode of Purchase (Retail, Non-Retail) - Trends & ... studies the market for the forecast period of 2016 ... 2.81 Billion by 2021 from USD 1.65 Billion in ...
(Date:6/23/2016)... June 23, 2016  MedSource announced today that ... e-clinical software solution of choice.  This latest decision ... value to their clients by offering a state-of-the-art ... relationship establishes nowEDC as the EDC platform of ... full-service clients.  "nowEDC has long been a preferred ...
(Date:6/23/2016)... 2016  In a startling report released today, National Safety ... lacking a comprehensive, proven plan to eliminate prescription opioid overdoses. ... how states are tackling the worst drug crisis in recorded U.S. ... Kentucky , New Mexico , ... Of the 28 failing states, three – Michigan ...
Breaking Medicine Technology: