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Can New Surgery Revolutionize Diabetes Treatment?
Date:5/14/2009

HOUSTON, May 14 /PRNewswire-USNewswire/ -- Metabolic surgery, a new surgical approach to metabolic disease, may provide the key to curing diabetes in some patients. This data was presented today at the American Association of Clinical Endocrinologists (AACE) 18th Annual Meeting & Clinical Congress.

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"This goes beyond just weight-loss surgery," Chief of Gastrointestinal Metabolic Surgery at Weill Cornell Medical College Francesco Rubino, MD, said. "For its clinical potential, and maybe even more for its implications for the understanding of diabetes, metabolic surgery is one of the most important research opportunities for the next decade in medicine."

According to Dr. Rubino, a growing body of evidence suggests that the mechanisms of diabetes resolution after surgery involve intestinal signals: "I am confident that we may see important discoveries occur as we direct our attention to the role of the bowel in diabetes."

Recent studies have indicated that bariatric surgery, an approach typically used to treat severe obesity, often results in normalization of blood sugar levels and other metabolic abnormalities. This results in a reduction of the overall risk of mortality associated with diabetes in severely obese patients.

Dr Rubino's personal research showed for the first time that the effects of bariatric surgery on diabetes cannot be entirely explained by weight loss, and are intrinsic with the change of intestinal anatomy characteristic of these procedures. As a result, experts have been studying the biological impacts of the surgery on mechanisms of glycemic control, and are exploring the possibility to use gastrointe
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SOURCE American Association of Clinical Endocrinologists
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