Navigation Links
Call to action: Running out of options to fight ever-changing 'super bugs'
Date:1/28/2009

People are dying from "super bugs" because our antibiotic arsenal has run dry, leaving the world without sufficient weapons to fight ever-changing bacteria, warn infectious disease researchers at The University of Texas Medical School at Houston.

In a Jan. 29 perspective in The New England Journal of Medicine, Barbara E. Murray, M.D., and Cesar Arias, M.D., Ph.D., evaluate the past, present and future response to preventing and treating "super bugs."

A "super bug" is an organism that is resistant to antibiotics. It can evade antibiotics by:

  • destroying the medication by producing an enzyme that devours the drug;
  • creating a barrier to the drug;
  • pumping out any antibiotic that reaches the bacterial cell;
  • modifying the target of the antibiotic so the drug can't bind to it.

"Most of the public has heard of MRSA (methicillin-resistant Staphylococcus aureus) because it produces the most cases each year. However, they have not heard of other super bugs that can be far worse," said Murray, co-author and director of Division of Infectious Diseases at the UT Medical School. "The Gram-negative bacteria are the most antibiotic-resistant with fewer treatment options in life-threatening diseases, such as certain forms of pneumonia, bloodstream infections, gastroenteritis and even meningitis." Gram-negative bacteria can release toxins created by their cell walls into the bloodstream, where it is harder to treat them.

According to a 2004 report, "Bad Bugs, No Drugs," by the Infectious Diseases Society of America (IDSA), none of the 89 new drugs approved by the U.S. Food and Drug Administration were antibiotics. Murray and Arias say people are also taking antibiotics without prescriptions or not following the prescription as directed. It is those practices that allow the antibiotics to be exposed to a wide-range of bacteria in the body, both good and bad, which gives the bugs an opportunity to find w
'/>"/>

Contact: Melissa McDonald
Melissa.E.McDonald@uth.tmc.edu
713-500-3308
University of Texas Health Science Center at Houston
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Hope In Action: Policymakers and Artists Promote Youth and Latino Suicide Prevention
2. Live Action: New Video Shows Indiana Planned Parenthood Covering Up Rape of 13-year old Girl
3. Running shipwreck simulations backwards helps identify dangerous waves
4. Pricey Running Shoes Not Worth It: Study
5. Kids Respiratory Virus Season Off and Running
6. Photo: Two Men Raising Awareness of HIV/AIDS by Running Minimum of a Marathon a Day from San Francisco to Los Angeles
7. OrthoLite Joins the Teva U.S. Mountain Running Team
8. Ex-Cowboys Running Back Ron Springs Named Plaintiff in Constitutional Challenge to Texas Malpractice Award Cap
9. Running Pioneer Kathrine Switzer Will Headline Women on the Move Conference August 13-15, 2008 in Spearfish, SD
10. 55-Year-Old Grandmother to Document Journey of Running Seven Marathons on Seven Continents on Run7on7.com
11. Wounded Marines Running Their Way to Recovery at Fourth Annual Pats Run
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/28/2014)... (HealthDay News) --,The more chronic medical conditions people have ... be, a new study claims. Since nearly ... scientists at Johns Hopkins Bloomberg School of Public Health ... gains in life expectancy are slowing in the United ... diabetes, kidney disease and heart failure is now the ...
(Date:7/28/2014)... News) -- Endurance runners are far more likely to ... according to a new study. The researchers ... warm climates are actually 10 times more likely to ... common sudden death of a young and apparently healthy ... irregular heartbeat, often gets a lot more media attention. ...
(Date:7/28/2014)... do not divide unless there is enough oxygen present ... other cell types circumvent this rule. Researchers at The ... overrides the cells, warning signals, enabling cancers to continue ... the process, the researchers found that lysosomes the ... decisions. They also uncovered new evidence that certain drugs ...
(Date:7/28/2014)... NY (PRWEB) July 28, 2014 Parker Waichman ... years fighting to ensure that the heroes of 9/11 are ... (VCF) has announced an important deadline. According to a ... diagnosed with a covered cancer on or before October 12, ... 12, 2014. First responders and others who were allegedly injured ...
(Date:7/28/2014)... (PRWEB) July 28, 2014 The ... that has donated more than 200,000 books to children ... announces the launch of Brooke’s Cooks, a new initiative ... encouraging healthy living among at-risk children and their families ... include a series of nutrition information workshops, cooking demonstrations ...
Breaking Medicine News(10 mins):Health News:Chronic Medical Conditions Can Shorten Seniors' Lives: Study 2Health News:Heat Stroke a Greater Threat to Endurance Runners Than Heart Problems: Study 2Health News:Cell's recycling center implicated in division decisions 2Health News:October 12, 2014 Deadline Approaching for 9/11 First Responders Suffering from Certain Cancers to Submit Their Registration to the VCF, Parker Waichman LLP Comments 2Health News:October 12, 2014 Deadline Approaching for 9/11 First Responders Suffering from Certain Cancers to Submit Their Registration to the VCF, Parker Waichman LLP Comments 3Health News:Brooke Jackman Foundation Launches Brooke's Cooks, New Initiative to Promote Healthy Living Among At-Risk Youth and Their Families 2Health News:Brooke Jackman Foundation Launches Brooke's Cooks, New Initiative to Promote Healthy Living Among At-Risk Youth and Their Families 3Health News:Brooke Jackman Foundation Launches Brooke's Cooks, New Initiative to Promote Healthy Living Among At-Risk Youth and Their Families 4
... contains significantly more females and includes a large proportion ... or specialized care, according to research published by researchers ... over-40 cohort, published online May 20 in the ... help guide future treatment of cystic fibrosis as survival ...
... finds , WEDNESDAY, May 19 (HealthDay News) -- For ... procedure called endovascular repair appears as good as conventional ... repair has been shown to have fewer complications and ... much shorter than with open surgery. However, questions remained ...
... next 40 years , WEDNESDAY, May 19 (HealthDay News) -- ... will more than double in the next 40 years, and the ... exceed $20 trillion, a new report from the Alzheimer,s Association finds. ... memory loss, -- it is a national crisis that grows worse ...
... men get liver cancer more often than women and opens the ... between the androgen receptor, which is more active in men, and ... The study is published May 19, 2010, in Science ... the Advancement of Science, AAAS. Primary liver cancer is the ...
... immune system in action, researchers say , WEDNESDAY, May 19 ... two different types of noninvasive probes to uncover the ... system. , One of the probes, known as an ... cells break down glucose (sugar), while the so-called FAC probe ...
... ... athlete in mind -- is proud to announce the launch of their latest collection ... time walk / run marathoners to seasoned triathletes and everyone in between. , ... (PRWEB) May 19, 2010 ...
Cached Medicine News:Health News:Older patients offer insight into the future of cystic fibrosis 2Health News:Older patients offer insight into the future of cystic fibrosis 3Health News:Less Invasive Fix for Abdominal Aortic Aneurysm Works 2Health News:Less Invasive Fix for Abdominal Aortic Aneurysm Works 3Health News:Alzheimer's Costs Could Explode by Mid-Century 2Health News:Androgen receptor may explain male dominance in liver cancer 2Health News:Androgen receptor may explain male dominance in liver cancer 3Health News:Androgen receptor may explain male dominance in liver cancer 4Health News:New Clues to Treating Immune System Disorders 2Health News:Inspired Endurance, E-tailer of Jewelry for Walkers, Runners, Marathoners and Triathletes, Introduces Endurance and Inspiration Beads Collection 2Health News:Inspired Endurance, E-tailer of Jewelry for Walkers, Runners, Marathoners and Triathletes, Introduces Endurance and Inspiration Beads Collection 3
(Date:7/28/2014)... , July 28, 2014 Southern Research ... , Ph.D., President and CEO of Southern Research ... Release Society (CRS) for the 2014-2015 term.  The ... on July 12 in Chicago ... The Controlled Release Society is ...
(Date:7/28/2014)...  MedSpring Urgent Care, an Austin -based health ... Blvd., Austin, TX 78704 on Saturday, July ... southeast corner of Barton Springs Rd. and S. Lamar ... p.m. daily, including weekends and holidays. With existing locations ... , Anderson Mill , Cedar Park ...
(Date:7/28/2014)... 28, 2014  ALPHAEON Corporation ® ... and subsidiary of Strathspey Crown Holdings ... Nutriceuticals (PRN) ® , a leading developer ... for dry eye and macular degeneration, ... worth up to $55M. ...
Breaking Medicine Technology:Arthur J. Tipton, Ph.D., Named President of Controlled Release Society 2Arthur J. Tipton, Ph.D., Named President of Controlled Release Society 3MedSpring Urgent Care opens Barton Springs walk-in clinic in Austin, TX 2ALPHAEON Acquires PRN, A Leading Specialty Nutriceutical Company 2ALPHAEON Acquires PRN, A Leading Specialty Nutriceutical Company 3
The REVEALRT and REVEALXVI PET/CT scanners combine our fastest PET scanner, the REVEALXL, with multi-slice spiral CT scanners from Siemens Medical Systems....
... a second generation device, having evolved from ... over 700 patients beginning in 1989. Designed ... cardiologists who perform these procedures, CardioSEAL has ... the engineering bench, and in animals. In ...
Allows surgeons to successfully complete coronary artery bypass without cross clamping or side biting. Saphaneous vein grafts may be attached to the aorta without sutures....
... treat a diverse range of patients suffering ... retinal disease. Compact, Space Saving Design - ... health care professionals to use the system ... Water-cooled: The power consumption is saved by ...
Medicine Products: