Navigation Links
Calcium during pregnancy reduces harmful blood lead levels
Date:9/9/2008

ANN ARBOR, Mich.---Pregnant women who take high levels of daily calcium supplements show a marked reduction in lead levels in their blood, suggesting calcium could play a critical role in reducing fetal and infant exposure.

A new study at the University of Michigan shows that women who take 1,200 milligrams of calcium daily have up to a 31 percent reduction in lead levels.

Women who used lead-glazed ceramics and those with high bone lead levels showed the largest reductions; the average reduction was about 11 percent, said Howard Hu, chair of the Department of Environmental Health Sciences at the School of Public Health.

Hu is the principal investigator of the study and one of the senior authors on the paper, which is available online in Environmental Health Perspectives, the official journal of the U.S. National Institute for Environmental Health Sciences. Hu, who is also affiliated with the University of Michigan School of Medicine, said this is the first known randomized study examining calcium supplementation on lead levels in pregnant women.

"We and others have previously shown that during pregnancy, mothers can transfer lead from their bones to their unborn -- with significant adverse consequences--making maternal bone lead stores a threat even if current environmental lead exposures are low," Hu said. "This study demonstrates that dietary calcium supplementation during pregnancy may constitute a low-cost and low-risk approach for reducing this threat."

Lead exposure is a great concern for pregnant and lactating women, especially in developing countries where lead exposures have been high until recently, and for women with occupational exposure. Developing fetuses and nursing babies are exposed to lead from either current exposures to mothers or from the mobilization of maternal skeletal lead stores accumulated from prior years of exposure. Bone lead can stay in the body for decades, so even with minimal environmental exposure, the fetus or nursing infant can still be at great risk from maternal stores of lead.

Lead exposure during fetal development and infancy can cause low birth weight or slow weight gain after birth, cognitive defects such as lower intelligence scores, lower motor and visual skills, or even miscarriage. Damage from lead exposure and poisoning is usually permanent.

"The bottom line is that obstetricians and pediatricians should consider adding calcium supplementation to the prenatal vitamins normally recommended in pregnant women, particularly if their patients have a significant history of environmental or occupational lead exposure," Hu said.

The study showed that reductions in blood lead levels were more evident in the second trimester at 14 percent than in the third trimester at 8 percent. The most compliant group of women in the study (those who consumed greater than 75 percent of the assigned 1,200 milligram doses of calcium per day) showed a 24 percent decrease. Women in the most compliant group who also reported using lead glazed ceramics and had the highest bone lead levels saw the greatest reduction of 31 percent.

Researchers analyzed 557 women recruited from the Mexican Social Security Institute prenatal clinics, which treat the low to moderate income population of Mexico City. All were in their first trimester; roughly half were assigned calcium and half a placebo.

This recent study corresponds with a previous study performed by the same group of investigators showing that 1,200-milligram daily calcium supplementation during lactation reduced maternal blood lead by 15-20 percent, and breast milk lead by 5-10 percent. This is the first randomized trial to evaluate the effect of supplementation during pregnancy, when lead is more easily transferred to the fetus, Hu said.


'/>"/>

Contact: Laura Bailey
baileylm@umich.edu
734-764-1552
University of Michigan
Source:Eurekalert

Related medicine news :

1. Study Links Serum Calcium, Prostate Cancer Death
2. Too much calcium in blood may increase risk of fatal prostate cancer
3. New study shows calcium significantly improves childrens bone health
4. Calcium may be the key to understanding Alzheimers disease
5. New study finds coronary arterial calcium scans help detect overall death risk in the elderly
6. Arterial Calcium Scans Can Predict Death Risk
7. New Calcium Measure Better Predictor of Heart Risks
8. Coronary calcium distribution tied to heart attack risk
9. Study shows that administering calcium and magnesium effectively reduces neurological sensitivity
10. African Americans at Risk for Low Calcium Intake - New Survey Finds Those Experiencing Symptoms of Lactose Intolerance May be Sidelining Dairy in Their Diets
11. Calcium Scans Help Predict Coronary Risk
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... ... June 27, 2016 , ... ... industry today announced its strategic partnership with Connance, a healthcare industry leader ... two companies’ proven, proprietary technology combine to provide health systems, hospitals and ...
(Date:6/26/2016)... ... , ... Pixel Film Studios Released ProSlice Levels, a Media Slicing Effect ... a whole new perspective by using the title layers in ProSlice Levels to ... ProSlice Levels contains over 30 Different presets to choose from. FCPX users ...
(Date:6/25/2016)... TX (PRWEB) , ... June 25, 2016 , ... Austin ... of the American College of Mohs Surgery and to Dr. Russell Peckham for medical ... and highly effective treatment for skin cancer. The selective fellowship in Mohs Micrographic Surgery ...
(Date:6/25/2016)... ... 25, 2016 , ... Dr. Calvin Johnson has dedicated his ... implemented orthobiologic procedures as a method for treating his patients. The procedure is ... to perform the treatment. Orthobiologics are substances that orthopaedic surgeons use to help ...
(Date:6/24/2016)... ... June 24, 2016 , ... June 19, 2016 is ... associated with chronic pain and the benefits of holistic treatments, Serenity Recovery Center ... suffering with Sickle Cell Disease. , Sickle Cell Disease (SCD) is a disorder of ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... INDIANAPOLIS , June 23, 2016 Roche ... received 510(k) clearance for its Elecsys BRAHMS PCT (procalcitonin) ... severe sepsis or septic shock. With this clearance, Roche ... provide a fully integrated solution for sepsis risk assessment ... associated with bacterial infection and PCT levels in blood ...
(Date:6/23/2016)... -- Research and Markets has announced the addition ... to their offering. The ... commercial environment for MedImmune to enter. The US ageing population ... to drive considerable growth for effective anti-influenza medications. The introduction ... considerably, but development is still in its infancy. ...
(Date:6/23/2016)... and INDIANAPOLIS , June ... receiving a Lilly Diabetes Tomorrow,s Leaders Scholarship is any ... scholarship winners, announced today online at www.diabetesscholars.org ... type 1 diabetes stand in the way of academic ... supported the Foundation,s scholarship program since 2012, and continues ...
Breaking Medicine Technology: