Navigation Links
Calcium May Cut Risk for Precancerous Colon Lesions in Some People
Date:4/10/2013

WEDNESDAY, April 10 (HealthDay News) -- Consuming higher amounts of calcium may lower the likelihood of precancerous colon and rectal lesions in people who are at increased risk due to variations in two genes, a new study suggests.

High calcium intake did not affect risk in people without the genetic variations.

The findings may help explain inconsistent results in previous research about the link between calcium intake and the risk for these lesions, called colorectal adenomas, the researchers said.

They also said the findings may help identify patients who would benefit from calcium supplements or higher levels of calcium in their diet.

The study of nearly 6,000 people in Tennessee found that patients with the highest calcium intake had no reduced risk for colorectal adenomas if they had no variations in two genes -- KCNJ1 and SLC12A1 -- that are essential in calcium reabsorption in the kidneys.

Fifty-two percent of the study participants had variations in at least one of the genes and 13 percent had variations in both genes. There was a strong association between high calcium intake and a 39 percent reduced risk of colorectal adenomas in those with a variation in one gene. High calcium intake was linked to a 69 percent reduced risk in those with variations in both genes.

The risk of advanced or multiple adenomas was 89 percent for people who had a high calcium intake and had variations in both genes, according to the study, which is scheduled for Wednesday presentation at the annual meeting of the American Association for Cancer Research, in Washington, D.C.

The findings suggest that a person with variations in one or both of the genes will have an increased risk for colorectal adenomas if they consume less than 1,000 milligrams of calcium a day, said study author Dr. Xiangzhu Zhu, a staff scientist with the epidemiology division in the department of medicine at Vanderbilt-Ingram Cancer Center in Nashville, Tenn.

"These patients should increase their calcium intake to reduce the risks," Zhu said in an association news release.

The findings could lead to genetic tests to identify people who would benefit from higher calcium intake, the researchers said. Although the research showed an association between increased calcium intake and lowered risk of adenomas, it did not prove a cause-and-effect relationship.

Because this study was presented at a medical meeting, the data and conclusions should be viewed as preliminary until published in a peer-reviewed journal.

More information

The American Cancer Society has more about colorectal cancer.

-- Robert Preidt

SOURCE: American Association for Cancer Research, news release, April 10, 2013


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Healthy Older Women Advised Against Taking Calcium
2. UCLA study finds endocrine disorder is most common cause of elevated calcium levels
3. Scientists find calcium is the initial trigger in our immune response to healing
4. Calcium Supplements May Raise Odds of Heart Death in Women
5. U of M researchers develop a molecular calcium sponge to tackle heart failure
6. Calcium Supplements May Raise Mens Death Risk From Heart Disease
7. Study shows high blood calcium levels may indicate ovarian cancer
8. Penn team developing new class of malaria drugs using essential calcium enzyme
9. Study shows heart calcium scan predictive of diabetes-related death from cardiovascular disease
10. Hebrew SeniorLife study finds no link between calcium intake and coronary artery calcification
11. Calcium, Vitamin D Supplements May Pose Risks for Men With Prostate Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Calcium May Cut Risk for Precancerous Colon Lesions in Some People
(Date:1/23/2017)... (PRWEB) , ... January 23, 2017 , ... ... for Assisted Living (IHCA/INCAL), will serve as a healthcare industry expert at the ... The panel discussion, moderated by Inside Indiana Business host Gerry Dick, will feature ...
(Date:1/23/2017)... ... January 23, 2017 , ... Old School Labs™, makers of the ... Classic Physique bodybuilder Breon Ansley to its growing team of brand ambassadors. The Olympia ... 2012 and in less than a year was able to turn professional, participating in ...
(Date:1/23/2017)... ARLINGTON, VA (PRWEB) , ... ... ... Seafood Nutrition Partnership (SNP) has launched online education programs and resources at ... health and nutritional benefits of a seafood-rich diet. These resources have been ...
(Date:1/22/2017)... , ... January 22, 2017 , ... Zifam Pinnacle, an ... the world, recently met with big-name retail buyers at the January ECRM Trade Show ... efficacy and uses the utmost safety standards in all of its creations to help ...
(Date:1/21/2017)... ... 21, 2017 , ... "ProDOF is the perfect set of tools for video editors that want ... scene," said Christina Austin - CEO of Pixel Film Studios. , Video editors using ... illusion of a DSLR racking focus from one area into the next. ProDOF comes ...
Breaking Medicine News(10 mins):
(Date:1/23/2017)...  Using Astute Medical,s NephroCheck Test ... kidney injury (AKI) after open-heart surgery and providing ... significantly improved outcomes by reducing the occurrence ... percent, according to a study published ... Medicine. Experience the interactive Multimedia ...
(Date:1/23/2017)... York , January 23, 2017 A ... Prenatal Testing Market was valued at US$0.53 bn in 2013 ... at a strong 17.50% CAGR between 2014 and 2022. The title ... Industry Analysis, Size, Volume, Share, Growth, Trends and Forecast 2014 - ... Non-invasive prenatal ...
(Date:1/23/2017)... , 23. Januar 2017  ResMed (NYSE: ... und 3B Medical ( Winter Haven, Florida ... Vereinbarung über die Beilegung aller globalen Rechtsstreitigkeiten zwischen den ... Verkauf ihrer bestehenden Produkte im Tausch gegen Lizenzgebühren ... an 3B leisten, um das in Florida ...
Breaking Medicine Technology: