Navigation Links
Calcium Helps Ward Off Colon Cancer
Date:2/23/2009

Effect is strongest for women, study finds, doesn't extend to other malignancies

MONDAY, Feb. 23 (HealthDay News) -- High dietary intake of calcium may reduce the incidence of colorectal cancer, especially for women, but has no apparent effect in reducing other malignancies, a U.S. National Cancer Institute study finds.

Why calcium should influence cancer risk differently in women versus men isn't clear, said Yikyung Park, a staff scientist at NCI who led the study. "One can speculate that hormonal or metabolic factors contribute to this difference," she said.

Park and her colleagues relied on data for nearly 500,000 men and women who participated in the U.S. National Institutes of Health-AARP Diet and Health Study. Participants filled out a food questionnaire when they enrolled and then were followed for an average of seven years.

"In both men and women, dairy food and calcium intakes were inversely associated with cancers of the digestive system," the researchers reported in the Feb. 23 issue of the Archives of Internal Medicine.

The top one-fifth of women with the highest intake averaged 1,881 milligrams of calcium per day. This group experienced a 23 percent lower risk of colon cancer than those women in the lowest fifth of intake, who averaged 494 milligrams daily. The comparable reduction for men was 16 percent.

The U.S. Institute of Medicine recommends a daily calcium intake of 1,200 milligrams for adults 50 and older, roughly the amount found in three cups a day of the dairy products that are the main sources of calcium. Other sources of calcium include sardines and green, leafy vegetables.

Calcium has been shown to reduce abnormal growths and induce normal turnover of cells in the gastrointestinal system, the report noted.

The study was done because "calcium has been hypothesized to play different roles in different cancer sites, but testing has been incomplete, inconsistent and limited," Park said.

One expert said the study is an important one. "This is the first paper looking at calcium, dairy products and all cancers combined," said Marji McCullough, strategic director of nutritional epidemiology at the American Cancer Society. The findings, she said, "were consistent with the previous literature."

For example, a controlled trial reported last year found no protective effect of calcium intake against breast cancer. The new report confirms that finding, and also finds that the nutrient offers no protective effect against prostate cancer.

The NCI study results "are consistent with guidelines for a healthy diet," McCullough said. "But it is important for people to understand that they shouldn't go overboard on calcium."

No additional protective effect was found for calcium intakes greater than 1,300 milligrams a day, according to the NCI study.

Current calcium recommendations are best met by dietary sources rather than supplements, McCullough added, in part because diet offers more than just calcium. "Calcium and vitamin D and are highly correlated in the diet, and it is difficult to isolate a single component," she said. "It may be that a combination of nutrients is important."

The combination of calcium of vitamin D is important, since vitamin D facilitates calcium's absorption by the digestive system. The skin makes vitamin D naturally through exposure to sunlight.

Another report in the same issue of the journal finds that that a combination of vitamins B6, B12 and folic acid appears to reduce the risk among women of age-related macular degeneration, a major cause of vision loss for older Americans.

A controlled trial including more than 5,400 women 40 and older found a 34 percent lower incidence of the eye disorder in women taking the vitamins compared to those taking an inactive placebo, said the report by researchers at Harvard Medical School and Brigham and Women's Hospital, Boston.

More information

There's more on dietary sources of calcium at the U.S. Library of Medicine.



SOURCES: Yikyung Park, Sc.D, staff scientist, U.S. National Cancer Institute, Bethesda, Md.; Marji McCullough, Sc.D, strategic director, nutritional epidemiology, American Cancer Society, Atlanta; Feb. 23, 2009, Archives of Internal Medicine


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Daily Calcium Does Protect Bone
2. International study strengthens case for daily calcium pill
3. Coronary Artery Calcium May Raise Womens Heart Risk
4. Calcium Supplements Could Raise Heart Risks in Postmenopausal Women
5. Scripps scientists find calcium channel blockers help normalize lysosomal storage disease cells
6. High Calcium Intake May Not Help Prevent Fractures, Reports The Harvard Health Letter
7. Calcium Scans Help Predict Coronary Risk
8. African Americans at Risk for Low Calcium Intake - New Survey Finds Those Experiencing Symptoms of Lactose Intolerance May be Sidelining Dairy in Their Diets
9. Study shows that administering calcium and magnesium effectively reduces neurological sensitivity
10. Coronary calcium distribution tied to heart attack risk
11. New Calcium Measure Better Predictor of Heart Risks
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Calcium Helps Ward Off Colon Cancer
(Date:5/26/2017)... , ... May 26, 2017 , ... “When the Stars ... Home” is the creation of published author Laura Weigel Douglas, an avid reader who ... in a house that sometimes feels like Green Hills Adventure Camp. She couldn’t be ...
(Date:5/26/2017)... ... 2017 , ... Centennial-based BluSky Restoration Contractors announced that The ... Clays for Kids fundraiser, to be held Friday, Sept. 22, at Kiowa Creek ... of BluSky’s partnership with The Adoption Exchange, BluSky will also share sponsorship with ...
(Date:5/26/2017)... , ... May 26, 2017 , ... “Cactus Jack: Against ... on so many others. “Cactus Jack: Against All Odds” is the creation of ... Walter D. Hubbard is married to Jack Carlisle’s third child Jane. Walter. Walter ...
(Date:5/24/2017)... ... May 24, 2017 , ... Last month, representatives from ... employees, and town officials to celebrate the grand opening of the 87,000 square ... as part of its ongoing relationship with RWJBarnabas Health, New Jersey’s largest health ...
(Date:5/24/2017)... ... May 24, 2017 , ... Dr. Alan I. Benvenisty, MD is dual board ... He is known for his distinguished expertise and experience in the diagnosis and treatment ... training in treating renovascular disease and aortic aneurysm . He is known for ...
Breaking Medicine News(10 mins):
(Date:5/22/2017)... 2017  As the specialty pharmacy industry and ... make the revolutionary shift from volume-based to value-based ... positive patient outcomes and shaping the future of ... away from clinical trials and toward data that ... drug therapy utilization in precise patient populations. Therigy ...
(Date:5/15/2017)... , May 15, 2017 Enterin Inc., a ... and developing novel compounds to treat Parkinson,s disease (PD), ... study is a Phase 1/2a randomized, controlled, multicenter study involving ... It will enroll 50 patients over a 9-to-12-month period. The ... in 10 patients with PD. Participating sites include ...
(Date:5/10/2017)... May 10, 2017 Global Health Intelligence ... Latin America , published its 2017 ranking of the ... based on extensive data analysis from GHI,s hospitals database ... database for the region. The GHI database covers 86% of ... more than 130 data points for each institution in key ...
Breaking Medicine Technology: