Navigation Links
Calcium, Vitamin D Supplements May Pose Risks for Men With Prostate Cancer
Date:8/9/2012

THURSDAY, Aug. 9 (HealthDay News) -- Although they're standard treatment for men with prostate cancer who are taking hormonal therapy, calcium and vitamin D supplements may do more harm than good, according to a new study.

Men who undergo hormone-depletion therapy for prostate cancer are at risk for osteoporosis, but the supplements do not prevent this bone loss and may actually boost patients' odds for heart disease and aggressive prostate cancer, research from Wake Forest Baptist Medical Center suggests.

"Calcium and/or vitamin D supplementation to prevent loss of bone mineral density in these men seems so logical that no one had questioned whether it works," study co-author, Mridul Datta, a postdoctoral fellow at Wake Forest Baptist, explained in a hospital news release.

"It wouldn't be so bad if there simply was no obvious benefit," added the study's lead author, Gary Schwartz, a prostate cancer epidemiologist at Wake Forest Baptist. "The problem is that there is evidence that calcium supplements increase the risk of cardiovascular disease and aggressive prostate cancer, the very disease that we are trying to treat."

In the study, the researchers reviewed guidelines for calcium and vitamin D supplements as well as the results of 12 clinical trials of these supplements involving almost 2,400 men with prostate cancer. All of the men were receiving hormone-deprivation therapy. The researchers also examined the men's bone mineral density before and after treatment.

According to the study, the men undergoing hormone therapy for prostate cancer who took the recommended daily doses of calcium and vitamin D supplements lost bone density.

The researchers also pointed out that increased dietary calcium is associated with a greater risk for aggressive prostate cancer and heart disease.

"The wake-up call of these findings," concluded Datta, "is that the presumption of benefit from calcium and vitamin D supplements that have been routinely recommended to these men must be rigorously evaluated."

The study's authors said more research is needed to confirm their findings and investigate the possible risks of calcium and vitamin D supplementation, particularly heart disease and prostate cancer.

One expert agreed that more study is needed.

The study authors "say that traditional approaches use too little calcium and/or vitamin D, but that as one increases the doses there are other risks, such as cardiovascular events," noted Dr. Louis Potters, a prostate cancer specialist and chair of radiation medicine at North Shore - LIJ Health System, in New Hyde Park, N.Y. "So that the trade-off for treating osteoporosis is associated with other risks."

Potters stressed that "not all men with prostate cancer need hormone therapy, only those with high-risk or advanced disease. And for those men, they need to have a discussion with their physician about the risks of these medications and how best to perhaps mitigate some of those risks."

The study was published online in the July issue of The Oncologist.

More information

The U.S. National Institutes of Health has additional information on prostate cancer.

-- Mary Elizabeth Dallas

SOURCES: Louis Potters, M.D., chair, radiation medicine, North Shore - LIJ Health System, New Hyde Park, N.Y.; Wake Forest Baptist Medical Center, news release, Aug. 7, 2012


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Older Women Should Not Take Calcium, Vitamin D: Task Force
2. Study questions value of calcium and vitamin D supplements
3. Low Vitamin D Levels May Raise Death Risk in Older Adults: Study
4. Vitamin D May Delay Deterioration of Smokers Lungs: Study
5. Vitamin D may protect against lung function impairment and decline in smokers
6. Adding Vitamin B12 to Standard Drugs Might Help Fight Hepatitis C
7. Vitamin E may lower liver cancer risk
8. Increase in RDA for vitamin C could help reduce heart disease, stroke, cancer
9. Vitamin D deficiency and poorer lung function in asthmatic children treated with steroids
10. Higher but not lower doses of vitamin D are effective in fracture risk reduction in older adults
11. Higher Doses of Vitamin D Prevent Fractures in Older Women
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Calcium, Vitamin D Supplements May Pose Risks for Men With Prostate Cancer
(Date:8/18/2017)... ... ... the Snake”: an entertaining and moral-based short story about an unkind snake learning a ... Jr., a husband, father and grandfather who served as a U.S. Marine, U.S. Army ... for children and teens. My goal is to teach kids to use good judgement ...
(Date:8/17/2017)... NC (PRWEB) , ... August 17, 2017 , ... ... dental practice, is adding a new location in Goldsboro, NC to its family ... care that is Riccobene Associates’ trademark starting August 15, 2017. , Riccobene ...
(Date:8/17/2017)... (PRWEB) , ... August 17, 2017 , ... ... series, proudly announces that it will feature the National Council for Therapeutic Recreation ... for more information. , Established in 1981, NCTRC is a non-profit, international organization ...
(Date:8/17/2017)... MA (PRWEB) , ... August 17, 2017 , ... ... will come together on September 19, 2017 for Anti-Infectives Rx. This off-the-record networking ... B. Martin Conference Center at Harvard Medical School. , Industry leaders and decision ...
(Date:8/17/2017)... GA (PRWEB) , ... August 17, 2017 , ... ... to welcome Dr. Kristi Hebert to its newest location in East ... enthusiastic to have Dr. Hebert come aboard,” said Dr. Mark A. Haber, Georgia Urology’s ...
Breaking Medicine News(10 mins):
(Date:8/4/2017)... , Aug. 3, 2017  Agragen, LLC, ... company active in the biopharmaceutical, nutraceutical, and aquacultural ... development of its lead drug candidates, AGR131.  This ... proinflammatory cytokine from the blood of patients suffering ... and inflammatory bowel disease. ...
(Date:8/2/2017)... Aug. 2, 2017   Marshall County Hospital in Benton, Kentucky ... the risk of hospital-acquired infections (HAIs). The new addition, Tru-D SmartUVC , short for ... kill deadly pathogens such as C. diff , MRSA, MERS, Ebola and more. ... Tru-D SmartUVC ... Tru-D in action in a patient room ...
(Date:8/1/2017)... CerSci Therapeutics , a non-opioid drug development firm based ... notice from the National Institute on Drug Abuse (NIDA) ... has been awarded a Direct-to-Phase II Small Business Innovation ... an additional $1,000,000 to follow in 2018. These funds ... lead non-opioid drug candidate CT-044 to the Food and ...
Breaking Medicine Technology: