Navigation Links
Cabazitaxel can offer an advantage in certain patients
Date:5/29/2012

s docetaxel in combination with prednisone or prednisolone.

Cabazitaxel can improve survival prospects

One study (TROPIC), which considered patient-relevant outcomes and provided relevant data, was included in the assessment of added benefit in the "best supportive care population". This study compared treatment with cabazitaxel versus mitoxantrone, in each case combined with prednisone and "best supportive care". In this context, mitoxantrone was regarded as a component of "best supportive care" for the assessment.

As IQWiG found, cabazitaxel can increase survival time, but the results vary with the age of patients. In patients aged 65 years or older, an indication of a major added benefit can be inferred with regard to overall survival. One can also assume an increase in survival time due to treatment with cabazitaxel in under 65-year-olds; however, the extent of this increase cannot be clearly determined, as the evidence base is less reliable here. In this age group, the data therefore only provide a "hint" of an added benefit, for which the extent cannot be quantified. The study also investigated the pain-relieving effect of the interventions as an aspect of the consequences of disease (morbidity). However, no relevant difference between the two treatment groups was shown. No data were available on health-related quality of life.

Also indication of greater harm due to severe side effects

In the "best supportive care population", the data also provide indications of greater harm in the form of side effects (adverse events). For example, severe adverse events, such as severe diarrhoea, anaemia or neutropenia, occurred more often in the cabazitaxel group. IQWiG classifies the extent of this greater harm as considerable for these outcomes. There is even an indication of major harm for the category "serious adverse events"; these are adverse events that, for example, lead to hospital admission, are life-thre
'/>"/>

Contact: Dr. Anna-Sabine Ernst
presse@iqwig.de
49-221-356-856
Institute for Quality and Efficiency in Health Care
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Cabazitaxel with radiation and hormone therapy may improve prostate cancer survival
2. Study Offers Ways to Decrease Use of Restraints at Nursing Homes
3. Prosthetic retina offers simple solution to restoring sight
4. Novel drug candidates offer new route to controlling inflammation
5. Botox Offers Little Relief for Migraine, Study Finds
6. Ice Cream Headaches Might Offer Clues to Migraines
7. Wilderness Medicine founder offers health tips for summer season
8. Here Are Fruits, Veggies That Offer Best Bang for Your Buck
9. Mayo Clinic offers newly approved treatment for acid reflux disease
10. Experts Offer Advice After Yankee Pitchers Trampoline Injury
11. Personalized immune mouse offers new tool for studying autoimmune diseases
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/1/2014)... New York (PRWEB) August 01, 2014 ... ) on behalf of women who allegedly experienced the ... power morcellators in gynecological surgeries, Bernstein Liebhard LLP notes ... withdraw a number of power morcellators marketed by its ... report from The New York Times, some critics of ...
(Date:8/1/2014)... Rochelle, NY, August 1, 2014Lesbian, gay, bisexual, and transgender ... the same problems as some of their heterosexual and ... they often face additional physiological and legal challenges ... recent advances in assisted reproduction options is presented in ... Future Possibilities ," published in LGBT Health ...
(Date:8/1/2014)... (PRWEB) August 01, 2014 Market ... research reports have been added to its catalogue. ... Active Pharmaceutical Ingredients (APIs), Contract Research and Manufacturing ... key pharma industry drivers include, among others, increasing ... personal hygiene. In 2015, the pharma market in ...
(Date:8/1/2014)... FRIDAY, Aug. 1, 2014 (HealthDay News) -- Patients with ... pulmonary disease (COPD) have a new weapon to battle ... Thursday. The agency approved a new treatment, ... the third leading killer of Americans. COPD, which is ... as chronic bronchitis and emphysema. Patients with ...
(Date:8/1/2014)... (PRWEB) August 01, 2014 The North ... endpoint security solutions market in North America with analysis ... grow from around $3.53 billion in 2014 to $4.77 ... 2014 to 2019. , Browse through the TOC of ... an idea of the in-depth analysis provided. It also ...
Breaking Medicine News(10 mins):Health News:Morcellator Lawsuit News: Bernstein Liebhard LLP Notes Reactions to Johnson & Johnson Power Morcellator Recall 2Health News:Morcellator Lawsuit News: Bernstein Liebhard LLP Notes Reactions to Johnson & Johnson Power Morcellator Recall 3Health News:Morcellator Lawsuit News: Bernstein Liebhard LLP Notes Reactions to Johnson & Johnson Power Morcellator Recall 4Health News:Advances in assisted reproduction create more options and new legal issues for LGBT couples 2Health News:In-demand Markets Research Reports by Kelly Scientific Publications Now Available at MarketPublishers.com 2Health News:In-demand Markets Research Reports by Kelly Scientific Publications Now Available at MarketPublishers.com 3Health News:FDA Approves New Treatment for People With COPD 2Health News:North America End-Point Security Market is Expected to Reach $4 billion in 2019 - New Report by MicroMarket Monitor 2Health News:North America End-Point Security Market is Expected to Reach $4 billion in 2019 - New Report by MicroMarket Monitor 3Health News:North America End-Point Security Market is Expected to Reach $4 billion in 2019 - New Report by MicroMarket Monitor 4
... promote cancer screening by announcing that only one in five ... to have an examination. But a new study published in ... Psychological Science, finds that this well-meaning message has the exact ... get screened. In an earlier study, Monika Sieverding ...
... HealthDay Reporter , MONDAY, July 26 (HealthDay News) ... the clot-dissolving drug tPA from 3 hours to up to ... any significant delays in treatment and appears to be a ... there was a slight increased risk of death and bleeding ...
... , MONDAY, July 26 (HealthDay News) -- Too many ... prostate-specific antigen (PSA) is normal or below normal, still ... evidence has shown that among older men with low-risk ... but another condition. For these men, watchful waiting is ...
... studies that compares two treatments for preventing strokes due carotid artery ... UT Southwestern Medical Center physician reports in an editorial in today,s ... "The most recent data on treatment options for carotid artery disease ... Dr. Ethan Halm, chief of the William T. and Gay F. ...
... Reporter , MONDAY, July 26 (HealthDay News) -- Doctors across ... open up clogged neck arteries to help prevent stroke, a ... fills up major arteries supplying blood to the brain, greatly ... the condition: an artery-scraping surgery called endarterectomy; the placement of ...
... cancer survival is associated with increased risk of long-term ... the July 26 issue of Archives of Internal ... to background in the article, childhood cancer survival rates ... roughly 70 to 80 percent currently. The authors also ...
Cached Medicine News:Health News:Few people are doing it, so why should I? Motivating men to seek cancer screening 2Health News:Longer Time Frame for Clot-Busting Drug May Help Beat Stroke 2Health News:Longer Time Frame for Clot-Busting Drug May Help Beat Stroke 3Health News:Most Men With Low-Risk Prostate Cancer Treated Aggressively, Study Shows 2Health News:Most Men With Low-Risk Prostate Cancer Treated Aggressively, Study Shows 3Health News:Surgery or stenting for carotid artery disease? Question remains 2Health News:Surgery or stenting for carotid artery disease? Question remains 3Health News:Stroke Prevention Treatment Varies Widely Across U.S. 2Health News:Stroke Prevention Treatment Varies Widely Across U.S. 3Health News:Stroke Prevention Treatment Varies Widely Across U.S. 4Health News:Childhood cancer survivors may have abnormal long-term cardiac function 2
(Date:7/31/2014)... 31, 2014  ResMed Inc. (NYSE: RMD ) ... fiscal year ended June 30, 2014.  Revenue for the quarter ... 30, 2013 (a 1 percent decrease on a constant currency ... percent compared to the quarter ended June 30, 2013. Diluted ... of 22 percent compared to the quarter ended June 30, ...
(Date:7/31/2014)... , July 31, 2014  Cepheid (NASDAQ: ... at the following conferences, and invited investors to participate via ... Conference, New York, NY Wednesday, August ... Baird Health Care Conference, New York, NY ... , Accessing Live Webcasts To access the live ...
(Date:7/31/2014)... Conn. , July 31, 2014  UBM Medica ... a leading online community for oncologists, presents exclusive slide ... that are essential to quality cancer care. ... journal ONCOLOGY , offers news, blogs, and podcasts ... for oncologists highlighting quality cancer care: , End-of-life ...
Breaking Medicine Technology:RESMED Inc. Announces Results for the Fourth Quarter and Fiscal Year 2014 2RESMED Inc. Announces Results for the Fourth Quarter and Fiscal Year 2014 3RESMED Inc. Announces Results for the Fourth Quarter and Fiscal Year 2014 4RESMED Inc. Announces Results for the Fourth Quarter and Fiscal Year 2014 5RESMED Inc. Announces Results for the Fourth Quarter and Fiscal Year 2014 6RESMED Inc. Announces Results for the Fourth Quarter and Fiscal Year 2014 7RESMED Inc. Announces Results for the Fourth Quarter and Fiscal Year 2014 8RESMED Inc. Announces Results for the Fourth Quarter and Fiscal Year 2014 9RESMED Inc. Announces Results for the Fourth Quarter and Fiscal Year 2014 10RESMED Inc. Announces Results for the Fourth Quarter and Fiscal Year 2014 11RESMED Inc. Announces Results for the Fourth Quarter and Fiscal Year 2014 12RESMED Inc. Announces Results for the Fourth Quarter and Fiscal Year 2014 13Cepheid to Webcast Upcoming Financial Presentations 2Cancer Network Highlights Methods Oncologists Can Use to Improve Communication 2Cancer Network Highlights Methods Oncologists Can Use to Improve Communication 3
... can be difficult for persons who have ... cord injuries and for children with poor ... other motor or coordination problems. The FoamWrap ... and coordination. Soft foam-lined material provides light ...
... a low profile contour at the palmar crease ... is an excellent choice to treat mild to ... or for wear following cast removal. The ... pile cinch fasteners provides support and compression to ...
... to treat DeQuervain's Tendonitis, strains and sprains ... advanced carpal tunnel syndrome and cumulative trauma ... Distal palmar crease contour allows for 90 ... Constructed from an open cell urethane ...
... is a solid, one-piece custom wrist orthotic designed to ... , ,Indications: , Wrist reconstruction , ... , Coles fracture - distal radius , ... , ORIF - Open reduction and internal ...
Medicine Products: