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CWRU's Beall elected to American Academy of Arts and Sciences
Date:4/25/2013

e College of Arts and Sciences at Case Western Reserve. "This is a very well-deserved recognition."

During her career, Beall has repeatedly changed the course of research in high-altitude human biology. She has shown that highlanders in the Andes and the Himalayas adapted differently to life in thin air. She and colleagues discovered the mechanisms that enable the populations to thrive where lowlanders face altitude sickness. Among Tibetans, they identified a major gene underlying one adaptive trait and found strong evidence of natural selectionwomen with the gene had twice as many children as those without. Later, they identified a genetic locus that associated with another adaptive trait and also gave strong evidence of natural selection.

More recently, she and fellow researchers have shown that Tibetans and the Amhara, an ethnic group that has lived high in the mountains of Ethiopia for more than 5,000 years, have the same adaptation that reduces the risk blood clots and strokecommon risks for lowlanders. But they found different genes are behind the adaptation, evidence of convergent evolution. That is, the two populations used different genetic means to the same biological end.

Beall and the rest of the 2013 class will be inducted at a ceremony on Oct. 12, 2013, at the Academy's headquarters in Cambridge, Mass.

She will join the academy's more than 4,600 Fellows and 600 Honorary Foreign Members who are leaders in mathematics, the physical and biological sciences, medicine, the social sciences and humanities, business, government, public affairs and the arts.

Among its Fellows are more than 200 Nobel Prize laureates and 100 Pulitzer Prize winners.

The academy continues to help set the national agenda for research and analysis in the arts and sciences. Major academy projects have focused on the changing nature and needs of higher education and research, the well-being of the humanities in the United States and the
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Contact: Kevin Mayhood
kevin.mayhood@case.edu
216-368-4442
Case Western Reserve University
Source:Eurekalert

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