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CWRU Dental School and UH Case Medical Center test possible oral cancer detection tool
Date:6/16/2014

with cancers of the head and neck.

  • Ratios of hBD2 to hBD3 in normal and lesional sites of the same patient will be determined by collecting cells by using a cone-shaped cytobrush swab.

  • Biopsies of questionable lesions will be taken to provide a diagnosis.

    The researchers hope to determine the ratio of hBD-2 to hBD-3 that differentiates cancerous lesions from normal tissue, and may, one day be used as a diagnostic tool for oral cancers, Weinberg said.

    "Our work will allow for a better understanding of the role hBD3 plays in the development of head and neck cancer, and help with the prompt identification and treatment of patients with oral squamous cell carcinoma," says Zender. "Our current understanding of oral cancer indicates that earlier diagnosis results in better outcomes."


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  • Contact: Susan Griffith
    susan.griffith@case.edu
    216-368-1004
    Case Western Reserve University
    Source:Eurekalert

    Page: 1 2 3

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