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CV risk management should be mandatory in RA and other types of inflammatory rheumatic disease
Date:6/13/2008

the CV management targets should be set according to local guidelines. If there are no local guidelines, treatment should be considered when the 10 year CV mortality risk with the (newly adapted) Framingham/SCORE function is above a certain value.

  • Aggressive inflammation suppression is recommended to further lower the CV risk in patients with inflammatory rheumatic disease.

    Dr Michael Nurmohamed, lead investigator and convenor of this EULAR Task Force said, "Although traditional cardiovascular risk factors occur more frequently in patients with inflammatory rheumatic disease than in the general population, they only partially explain these patients' increased cardiovascular risk. There is mounting evidence that inflammation may be the missing link. Therefore, disease modifying antirheumatic drugs (DMARD) and biologics may lower the cardiovascular risk in inflammatory rheumatic disease patients, whilst statins and hypertensives, such as ACE inhibitors and angiotensin blockers, may even yield greater benefits than in the general population due to their anti-inflammatory properties."

    Professor Ferdinand Breedveld, President of EULAR said, "These recommendations have been developed in accordance with the EULAR Standardised Operating Procedures and in line with the EULAR objectives to improve the understanding of musculoskeletal disorders and contribute to the improvement of outcome of patients with rheumatic disorders. The Task Force is to be commended on its excellent recommendations which will directly contribute to improved clinical practice and better understanding of the management of CV factors in rheumatology."

    CV risk factor stratification and management is currently conducted on the basis of 10 years absolute risk for a (fatal) CV-event, as derived from a risk formula based on a number of CV-risk factors. The two major standard CV risk calculators are Framingham, a tool based on US population statistics and SCORE,
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  • Contact: Rory Berrie / Camilla Dormer
    eularpressoffice@uk.cohnwolfe.com
    44-077-892-70392
    European League Against Rheumatism
    Source:Eurekalert

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