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CTI Focuses on Late-Stage Drug Approvals and Commercialization and Cuts Operating Costs: to Close Bresso Research Center
Date:2/27/2009

positioning of novel discovery platforms. The firm maintains offices in Bethesda, MD and San Jose, CA. For more information about Adjuvant Global Advisors, please visit www.adjuvant.com

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This press release includes forward-looking statements that involve a number of risks and uncertainties, the outcome of which could materially and/or adversely affect actual future results. Specifically, the risks and uncertainties that could affect future results include the risks associated with preclinical and clinical developments in the biopharmaceutical industry in general, the determinations by regulatory, patent and administrative governmental authorities, competitive factors, technological developments, potential failure of pixantrone to prove safe and effective for treatment of relapsed aggressive NHL as determined by the FDA, marketing approval review of the OPAXIO MAA may not result in a marketing approval in Europe, the costs of developing, producing and selling pixantrone and OPAXIA, the risk that Novartis may not elect to participate in the development and marketing of OPAXIO or may not exercise its option with regard to pixantrone, the Company may not be successful in identifying or completing a partnership, asset divestiture or joint venture with respect to the Bresso facility, the Company may not be successful in reducing its cash burn rate, the Company continues to have negative cash flow and a significant amount of debt outstanding; the Company will not be able to raise additional capital to fund its continued operations; and the risk factors listed or described from time to time in the Company's filings with the Securities and Exchange Commiss
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