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CT scans for lung cancer screening may be beneficial in detecting COPD
Date:10/25/2011

CHICAGO Among men who were current or former heavy smokers, undergoing lung cancer screening with computed tomography (CT) scanning identified a substantial proportion who had chronic obstructive pulmonary disease (COPD), suggesting that this method may be helpful as an additional tool in detecting COPD, according to a study in the October 26 issue of JAMA.

"Smoking is annually projected to cause more than 8 million deaths worldwide in the coming decades. Besides cardiovascular disease and cancer, chronic obstructive pulmonary disease is a major cause of death in heavy smokers. Nevertheless, COPD is substantially underdiagnosed. Despite a decrease in cardiovascular mortality and stabilization of cancer mortality worldwide, mortality from COPD is increasing," according to background information in the article. Early cessation of smoking can prevent COPD progression, underscoring the importance of early detection. Computed tomography-based lung cancer screening may provide an opportunity to detect individuals with COPD at an early stage.

Onno M. Mets, M.D., of the University Medical Center Utrecht, the Netherlands, and colleagues conducted a study to examine whether low-dose lung cancer screening CT scans could be used to identify participants with COPD. The study, conducted within an ongoing lung cancer screening trial, included prebronchodilator pulmonary function testing with inspiratory (inhalation of air into the lungs) and expiratory (exhalation of air from the lungs) CT scans performed on the same day from 1,140 male participants between July 2007 and September 2008. The pulmonary function tests were used as the reference standard in determining the COPD diagnostic accuracy of the CT scans.

The average age of participants was 62.5 years. Data for self-reported respiratory symptoms were available from 1,085 participants; a total of 566 participants were symptomatic, and 519 participants were asymptomatic. Forty-one partic
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Contact: Pim A. de Jong, M.D., Ph.D.
pimdejong@gmail.com
JAMA and Archives Journals
Source:Eurekalert

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