Navigation Links
CT scan is cost-effective in screening for LAM among women with collapsed lung
Date:3/4/2010

CINCINNATIResearchers at the University of Cincinnati (UC) have found that it is cost-effective to do CT scan screening of non-smoking women, ages 25-54, who come to the emergency room for the first time with a collapsed lung in order to diagnose and treat those with lymphangioleiomyomatosis, or LAM.

This data is being featured in the online edition of the American Journal of Respiratory and Critical Care Medicine.

LAM is a rare but serious lung disease that occurs when an unusual type of cell begins to grow out of control and spread to restricted areas in the body, including the lungs, kidneys, lymph nodes and vessels.

"Women with LAM who first experience spontaneous lung collapse will, on average, experience two more," says Brent Kinder, MD, an investigator in the study. "LAM diagnosis doesn't usually occur until the second or third collapse occurs, delaying treatment. We thought that targeting screening to non-smoking women in the age range of typical LAM development may help us identify the condition earlier and improve quality of life for these patients."

Kinder and Jared Hagaman, MD, along with colleagues in the department of medicine, developed a model to evaluate the cost-effectiveness of screening patients for LAM. Using national representative data sources, researchers looked at rates of collapsed lung and prevalence of LAM in relation to age, gender and smoking status.

They compared the benefit and cost of using high-resolution CT screening following lung collapse for patients with LAM to no CT screening. Costs of testing and treatment were taken from 2007 Medicare data.

Based on the model patient who comes into the emergency room with a spontaneous lung collapsea 30-year-old, non-smoking femaleabout 5 percent test positive for LAM.

"Screening for LAM using a CT, or three-dimensional X-ray of the lungs, is the most cost-effective strategy, with approximately $32,000 per quality-adjusted life year gained. For comparison, hemodialysis, a standard benchmark for cost-effectiveness, costs about $50,000 per quality-adjusted life year gained," he says. "We believe the benefits of testing outweigh any negative impact on patients with LAM. The radiation dose of a high-resolution CT scan is approximately one-tenth of conventional CT scans, and with newer technology, the radiation exposure continues to decrease.

"This data will help physicians intervene with therapies more quickly and enroll patients in clinical trials that may be able to slow progression of the disease."


'/>"/>

Contact: Katie Pence
katie.pence@uc.edu
513-558-4561
University of Cincinnati Academic Health Center
Source:Eurekalert

Related medicine news :

1. CT-scan screening for LAM in women with collapsed lung is cost-effective
2. Mammogram Plus MRI Cost-Effective in High-Risk Women
3. Mammogram Plus MRI Seems Cost-Effective in High-Risk Women
4. Screening for Spinal Muscular Atrophy Not Cost-Effective: Study
5. BIA and Catalyst Release Per-Document Review & Hosting, a Cost-Effective Package
6. Cost-effective PC-based EKG Now Available from DRE
7. Live Webinar: Pandemic + Recession = Webcasting: Cost-Effective Streaming for Public Health Communications
8. Organized phone therapy for depression found cost-effective
9. Vaccinating boys against human papillomavirus not cost-effective
10. Private umbilical cord banking not cost-effective, UCSF research shows
11. Alere Executive Keynote at DMAA Conference Stresses Combining Medical and Health Improvement Models to Bring About Cost-Effective Changes in Healthcare Reform
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/6/2016)... ... 2016 , ... Of the variety of ingredients in the food supply, few ... to common beliefs that hot dogs include “everything but the oink,” today’s wieners are ... combined with meat and poultry in a hot dog recipe can add flavor, keep ...
(Date:12/6/2016)... ... 06, 2016 , ... The NALA, a boutique marketing agency, is proud to ... (TBCF), a nonprofit 501(C)(3) organization providing financial and emotional support to families of children ... TBCF, the NALA recently hosted a Thanksgiving food drive that resulted in four boxes ...
(Date:12/6/2016)... ... December 06, 2016 , ... The Behavioral Health Center of ... the organization as a top behavioral service provider in the country. The award ... staff satisfaction and qualifications, and consumer satisfaction. These areas are measured via a ...
(Date:12/6/2016)... ... December 06, 2016 , ... Experimentation ... research and development, largely due to its potential for revolutionizing human disease treatment. ... and human induced pluripotent stem cells (hiPSCs). , Both platforms have distinct ...
(Date:12/6/2016)... Switzerland (PRWEB) , ... December 06, 2016 , ... ... a one-stop portal for all the knowledge resources, including white papers, guides, ... certificates, and more. , To access more than 9,000 documents, webinars and ...
Breaking Medicine News(10 mins):
(Date:12/5/2016)... , Dec. 5, 2016   Mallinckrodt Pharmaceuticals ... pharmaceutical company, today announced that it received a perfect ... Index (CEI), a national benchmarking survey and report on ... and transgender (LGBT) workplace equality, administered by the Human ... 517 major U.S. businesses which also earned top marks ...
(Date:12/5/2016)... 5, 2016  Cornerstone Pharmaceuticals, Inc., a privately ... from two Phase I trials evaluating its lead ... annual meeting of the American Society of Hematology ... . The two datasets show encouraging efficacy and ... (AML) and T-cell non-Hodgkin,s lymphoma (T-cell NHL), respectively, ...
(Date:12/5/2016)... BOULDER, Colo. , Nov. 29, 2016 ... webinar hosted by Accera, Inc. at 11 ... 9th Annual International Conference on Clinical Trials for Alzheimer,s ... role of metabolism in Alzheimer,s disease and therapeutic targets ... patients. "Following the recent failure of another ...
Breaking Medicine Technology: