Navigation Links
CT depicts racial differences in coronary artery disease
Date:11/27/2012

CHICAGO While obesity is considered a cardiovascular risk factor, a study presented today at the annual meeting of the Radiological Society of North America (RSNA) showed that African-American patients with coronary artery disease (CAD) have much less fat around their hearts compared to Caucasian patients.

"Prior evidence suggests that increased fat around the heart may be either an independent marker of CAD burden or a predictor of the future risk of acute coronary events," said U. Joseph Schoepf, M.D., professor of radiology and medicine and director of cardiovascular imaging at the Medical University of South Carolina in Charleston, S.C. "You would think that African Americans, who have a higher prevalence of CAD, would have higher rates of thoracic fat in an acute chest pain setting. However, this was not the case. White patients had significantly higher thoracic fat volumes than African-American patients."

According to the Centers for Disease Control and Prevention, coronary heart disease is the leading cause of death for people of most ethnicities in the United States. In 2010, the age-adjusted prevalence of coronary heart disease was 6.5 percent among African Americans, compared to 5.8 percent among Caucasians.

"We were very interested in finding an explanation for the racial difference in CAD and suspected differences in thoracic adipose tissue between races might be one of the contributing factors," said Paul Apfaltrer, M.D., from the Institute of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Heidelberg University, Germany.

For the study, researchers evaluated cardiac dual-source CT images of 411 age- and gender-matched African-American and Caucasian patients, quantifying thoracic fat volumes, including epicardial adipose tissue (EAT)body fat that is in direct contact with the heartand mediastinal adipose tissue, which is body fat within the chest cavity. Results showed that while the prevalence of significant stenosis, or narrowing of the coronary ducts, and plaque was similar in African-American and Caucasian patients, African-American patients had less fat around their hearts.

The findings, Drs. Schoepf and Apfaltrer say, are surprising, given the higher number of cardiac and metabolic disorders among African Americans despite presence of less fat in the chest cavity. The researchers suggest that EAT may actually act as a protective buffer, or that it may be related to plaque maturation including calcification, and could contribute to lower risk of acute coronary events.

"Understanding the mechanism behind the racial disparities we found may improve the prevention, risk stratification and management of CAD," Dr. Schoepf said.


'/>"/>

Contact: Linda Brooks
lbrooks@rsna.org
630-590-7762
Radiological Society of North America
Source:Eurekalert

Related medicine news :

1. Vanderbilt-led study reveals racial disparities in prostate cancer care
2. Racial differences in diabetes diagnostic thresholds
3. Black gay men worldwide 15 times more likely to have HIV and racial disparity
4. New CDC study on racial disparities in infant mortality published in Journal of Womens Health
5. Multiracial youths show similar vulnerability to peer pressure as whites
6. Racial Gap in Kids Dental Care Vanishing: Study
7. Racial make-up of community impacts obesity risk
8. UC Irvine study finds racial, economic disparities in ovarian cancer care, survival
9. Researchers discover gender-based differences in Alzheimers disease
10. Stanford/Yale study gives insight into subtle genomic differences among our own cells
11. Scientists Find Gene Differences in Nonsmokers With Lung Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... LEXINGTON, Ky. (PRWEB) , ... October 13, 2017 , ... ... MD, MPH to become its next President and Chief Executive Officer, succeeding Dr. James ... and CEO Elect beginning July 1, 2018 until Dr. Puffer’s retirement at the end ...
(Date:10/13/2017)... ... October 13, 2017 , ... Lori R. Somekh, founder ... of ElderCounsel, a national organization of elder law and special needs planning attorneys. “Membership ... rules. It also provides a forum to network with elder law attorneys nationwide,” said ...
(Date:10/13/2017)... ... 13, 2017 , ... Ellevate Network, the leading network for professional women, brought ... gender equality at their inaugural Summit in New York City in June. The event ... audience of over 3 million. To watch the Mobilize Women video, click here ...
(Date:10/13/2017)... ... 13, 2017 , ... Coveros, a leader in agile coaching ... contract by the Center for Medicare and Medicaid Services (CMS). The Enterprise Agile ... of Agile methodologies in a consistent and high value manner across CMS programs. ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... treating sleep apnea using cutting-edge Oventus O2Vent technology. As many as ... disorder characterized by frequent cessation in breathing. Oral appliances can offer significant relief ...
Breaking Medicine News(10 mins):
(Date:10/4/2017)... Oct. 4, 2017  South Korean-based healthcare product Development ... aide "cprCUBE" on Kickstarter. The device will educate the ... arrests with better efficiency compared to the dated and ... feedback on efficacy of the compression for a more ... a goal to raise $5,000. ...
(Date:10/2/2017)... 2, 2017  AllianceRx Walgreens Prime, the combined central ... and pharmacy benefit manager Prime Therapeutics LLC (Prime), today ... included the unveiling of new signage at its headquarters ... as at a few other company-owned facilities across the ... patients, some of whom will begin to see the ...
(Date:9/27/2017)... -- Commended for their devotion to personalized service, SMP Pharmacy Solutions ... in the South Florida Business Journal,s 50 Fastest-Growing Companies, and ... the national specialty pharmacy has found its niche.  To that ... be honored by SFBJ as the 2017 Power Leader in ... receive his award in October, Bardisa said of the three ...
Breaking Medicine Technology: