Navigation Links
CT and serum LDH shows promise as survival predictor for some metastatic melanoma patients
Date:4/16/2013

Combining CT imaging findings with baseline serum lactate dehydrogenase levels is showing promise as a way to predict survival in patients with metastatic melanoma being treated with anti-angiogenic therapy.

With the hope of predicting patient survival, researchers at the University of Mississippi Medical Center in Jackson and at the Ohio State University Comprehensive Cancer Center in Columbus analyzed CT images and clinical data from 46 patients with metastatic melanoma that were treated with anti-angiogenic therapy. "The analysis found that initial post-therapy CT imaging changes in tumor morphology, attenuation, size and structure (MASS Criteria) are predictive of survival. These results are similar to what we have found in patients with metastatic kidney cancer, another highly vascular tumor treated with anti-angiogenic therapy. The current study is the first of its kind to associate CT findings of tumor devascularization with survival in patients with metastatic melanoma treated with anti-angiogenic therapy," said Dr. Andrew Smith of the University of Mississippi.

"Patients with high baseline serum lactate dehydrogenase (LDH) tend to have poor overall survival compared to patients with low serum LDH," said Dr. Smith. LDH levels are used to stage metastatic melanoma, but are only weakly associated with survival when used alone," he said. "What was surprising to us was that the accuracy for predicting both progression-free and overall survival is substantially increased when MASS Criteria findings are combined with data from serum LDH levels," said Dr. Smith.

"This was an exploratory study," said Dr. Smith. "The next step is to take what we've discovered and test it in prospective clinical trials. At a minimum, patients with low baseline serum LDH and evidence of tumor devascularization on their initial post-therapy CT should be encouraged that they are likely to have a favorable response to therapy," he said.

"Th
'/>"/>

Contact: Samantha Schmidt
sschmidt@arrs.org
703-858-4316
American Roentgen Ray Society
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Low levels of serum bilirubin spell higher lung cancer risk for male smokers
2. New - Renaissance Age Serum, a Revival in Swiss Anti-Aging Skin Care; Improve Skin Texture for a More Youthful Appearance using Gerda Spillmann’s Newest Anti-Aging Serum
3. Some minorities believe they are less likely to get cancer compared to whites, Moffitt study shows
4. Study shows severity of sleep apnea is influenced by race
5. Stanford study shows different brains have similar responses to music
6. 2-drug combo more effective in treating sarcomas, Moffitt Cancer Center study shows
7. Experimental Vaccine Shows Promise for Ovarian Cancer
8. 2-step ovarian cancer immunotherapy made from patients own tumor shows promise
9. CAMH study shows mental illness associated with heavy cannabis use
10. More Evidence Shows Hormone Therapy May Increase Breast Cancer Risk
11. New technique shows promise in restoring near vision without glasses
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/3/2015)... Burnsville MN (PRWEB) May 03, 2015 ... in workplace safety solutions, announces its appearance at the ... Health Conference. Products that HealthPostures will exhibit at the ... Largest of the sit stand solutions is the 6100 ... push button height control, an adjustable keyboard tray, extended ...
(Date:5/2/2015)... Ticket Down has secured additional inventories of ... awaited event today, Saturday, May 2nd at the MGM Grand ... be able to secure tickets for both the actual fight ... fans have wanted for more than five years was finally ... will step inside the ring to fight Manny “Pac-Man” Pacquiao ...
(Date:5/2/2015)... “ ActOn ” was featured on NewsWatch as part ... latest and coolest applications on the market for iOS, Android, ... expert, conducted the app review and shared with viewers how ... make a difference. , In this material world, almost everything ... about money, which is why those things should be prioritized ...
(Date:5/2/2015)... May 02, 2015 It’s a pattern ... natural disaster strikes anywhere on this planet, cyber scammers ... sympathy and compassion for their own personal gain. ... Emergency Readiness Team) issued an alert titled “Nepal ... email scams citing the earthquake in Nepal. The scam ...
(Date:5/2/2015)... “ Peachtree Audio ” was featured on NewsWatch as ... latest and coolest technology products available to consumers. Scott ... conducted the review and shared with viewers how this ... an important part of people’s lives – and as ... treatment. Peachtree Audio does just that with high-end audio ...
Breaking Medicine News(10 mins):Health News:HealthPostures to Appear at the Minnesota Safety and Health Conference 2Health News:HealthPostures to Appear at the Minnesota Safety and Health Conference 3Health News:Cheap Floyd Mayweather vs. Manny Pacquiao Tickets: Ticket Down Has Last Minute Tickets for Mayweather vs. Pacquiao at the MGM Grand Garden Arena in Las Vegas 2Health News:Cheap Floyd Mayweather vs. Manny Pacquiao Tickets: Ticket Down Has Last Minute Tickets for Mayweather vs. Pacquiao at the MGM Grand Garden Arena in Las Vegas 3Health News:An Application to Help People Make a Difference Was Featured on NewsWatch Television 2Health News:Cyber Aftershocks from Nepal’s Earthquake Can Cripple Businesses Right Here at Home 2Health News:Cyber Aftershocks from Nepal’s Earthquake Can Cripple Businesses Right Here at Home 3Health News:Cyber Aftershocks from Nepal’s Earthquake Can Cripple Businesses Right Here at Home 4Health News:Affordable High-End Audio Equipment was Featured on NewsWatch Television 2
... health researchers are warning that some of the most important ... yet this issue is unlikely to be given much attention ... Dr Lisa Page and Dr Louise Howard from the ... range of recent research by scientists into the potential mental ...
... ... nationwide honors to several deserving recipients during its national meeting in Atlanta. , ... (PRWEB) December 3, 2009 ... its national meeting on Nov. 20 in Atlanta. The honorees are as follows: ...
... ... pressure as well as increase the risk of obesity. Treadmill desks have been show ... , ... (Vocus) December 3, 2009 -- Two sleep studies illustrating the negative effects of sleep ...
... , , YOUNGTOWN, Ariz., Dec. ... announced today that it has acquired SunView Care Center, an ... sister community adjacent to Arizona,s Sun City retirement community. The ... http://www.newscom.com/cgi-bin/prnh/20071213/LATH168LOGO ) , "We are pleased to be adding ...
... MINNEAPOLIS, Dec. 3 The American Association of Poison Control ... Minnesota as an accredited poison control center - a major ... places the Hennepin Regional Poison Center among 58 accredited poison ... accomplishment. It means we have met the national standards of ...
... , WASHINGTON, Dec. 2 In response to a ... Now ," an initiative from the U.S. Anti-Doping Agency ... leading trade association representing the dietary supplement industry, issued the following ... , President and CEO: , "We share the concerns ...
Cached Medicine News:Health News:Major impacts of climate change expected on mental health 2Health News:Arthritis Foundation Bestows Highest National Awards 2Health News:Arthritis Foundation Bestows Highest National Awards 3Health News:Arthritis Foundation Bestows Highest National Awards 4Health News:Treadmill Desks Lower Health Risks Caused by Lack of Sleep 2Health News:The Ensign Group Acquires Arizona Skilled Nursing Facility 2Health News:Hennepin Regional Poison Center Designated as an Accredited Poison Control Center 2Health News:CRN Responds to 'Supplement Safety Now' Initiative 2Health News:CRN Responds to 'Supplement Safety Now' Initiative 3
(Date:5/1/2015)... --  Heska Corporation (NASDAQ: HSKA - ... advanced veterinary diagnostic and other specialty veterinary products , today ... at the 16th Annual B. Riley & Co. Investor Conference ... will be held May 12-14, 2015 at Lowes Hollywood Hotel, ... be available during the day on May 13 for one-on-one ...
(Date:5/1/2015)... , May 1, 2015 The Institute ... 2015 health literacy award winners. The IHA Health Literacy ... make an impact on the practice of educating or ... literacy. IHA gives awards in three categories: innovative programs, ... its Health Literacy Hero award. In the ...
(Date:5/1/2015)... , May 1, 2015  Misonix, Inc. ... company that designs, manufactures and markets innovative therapeutic ... wound debridement, cosmetic surgery, laparoscopic surgery and other ... financial results for the third quarter fiscal year ... has scheduled a conference call that same day, ...
Breaking Medicine Technology:Heska to Present at the 16th Annual B. Riley & Co. Investor Conference 2Institute for Healthcare Advancement Announces 2015 Award Winners 2Misonix, Inc. To Report Third Quarter Fiscal Year 2015 Financial Results On Thursday, May 7, 2015 2
... Renowned biochemist Michael A. Marletta, PhD, has been named by ... The Scripps Research Institute, effective January 1, 2012. He will ... institution for 25 years. Image available at: ... Chair of the Department of Chemistry, Co-Director of the Chemical ...
... Calif., Feb. 25, 2011 As a world leader ... prostate cancer, the Smilow Comprehensive Prostate Cancer Center ( ... Medical Center is the first medical facility in the ... navigation system for prostate biopsy that is manufactured by ...
Cached Medicine Technology:The Scripps Research Institute Names Michael A. Marletta as President 2The Scripps Research Institute Names Michael A. Marletta as President 3The Scripps Research Institute Names Michael A. Marletta as President 4The Smilow Comprehensive Prostate Cancer Center Installs Eigen ei-Nav|Artemis™ 2The Smilow Comprehensive Prostate Cancer Center Installs Eigen ei-Nav|Artemis™ 3
... CIC are formed as a host ... cleared by phagocytosis. If not cleared, CIC ... inflammatory response. CIC are increased in Systemic ... may be involved in other autoimmune disorders ...
Microalbumin Linearity Control...
The K-ASSAY Lipid Controls are assayed controls produced from fresh human sera to monitor the accuracy and precision of quantitative lipid determinations of human sera specimens....
... ASO / RF / CRP ... be used as a consistent ... for monitoring the performance of ... Factor (RF), and C-Reactive Protein ...
Medicine Products: