Navigation Links
CT Scans Catch More Clots in Lungs
Date:12/18/2007

Study finds newer method slightly more effective than traditional lung scans,,,,

TUESDAY, Dec. 18 (HealthDay News) -- Pulmonary embolism -- a life-threatening blood clot in the lungs -- can be very difficult to diagnose, but new research suggests a technique using CT scanning might be slightly more effective than lung scans at spotting such clots.

Canadian researchers found that computed tomographic pulmonary angiography (CTPA) detected pulmonary embolisms in 19.2 percent of a group of study volunteers who'd had symptoms of a pulmonary embolism, compared to 14.2 percent of the group who underwent the more standard test, ventilation/perfusion (V/Q) lung scanning.

More important, a pulmonary embolism was missed in only two out of the 561 people who underwent CTPA versus six out of 611 people who'd had V/Q scans. If a pulmonary embolism goes undetected and untreated, almost one-third of people with this type of blood clot will die.

"CTPA can safely be used to exclude the diagnosis of pulmonary embolism," said study author Dr. David R. Anderson, head of the division of hematology at Dalhousie University and Capitol Health in Halifax, Nova Scotia.

"We ended up diagnosing more patients with pulmonary embolism with CTPA rather than V/Q scanning. That was a bit of a surprise," said Anderson, who added that this finding needs to be investigated further. "Sometimes, when you detect very small blood clots that are isolated to single vessels, clinically, we wonder if such a small abnormality is the cause of symptoms."

Results of the study are published in the Dec. 19 issue of the Journal of the American Medical Association.

"In general, the tendency is that when a clot is found, unless there's a specific contraindication, the clot is treated, because we recognize that clots can be very serious, and they can recur," said Dr. Jeffrey Glassroth, vice dean and chief academic officer at the Feinberg School of Medicine at Northwestern University in Chicago. Glassroth is also the author of an accompanying editorial.

However, the anticoagulant medicines used to treat blood clots aren't without risk. In some people, these medications can cause excessive bleeding that can be life-threatening. So, it's important to accurately diagnose pulmonary embolism. "There's a definite downside to treating unnecessarily," Anderson noted.

For the past 30 years, V/Q scanning has been the tool most often used to diagnose pulmonary embolisms. The test requires an injection of a radioactive tracer and the inhalation of radioactive gas. CTPA has been around for about 10 years and also involves using an injected radioactive tracer but doesn't require the inhalation portion included in V/Q scans. The cost of the two procedures is similar, but there's a slightly higher chance of a reaction to the contrast material used in CTPA, and the radiation dose from the imaging technique is higher with CTPA, according to Glassroth.

While CTPA quickly became an accepted alternative, it wasn't clear how the two methods compared to each other. To answer that question, Anderson and his colleagues recruited 1,417 people being treated for symptoms of pulmonary embolism.

Seven hundred and one of the study volunteers had CTPA to rule out pulmonary embolism, while 716 had V/Q scans. Almost 20 percent of those undergoing CTPA were diagnosed with a pulmonary embolism, compared to 14.2 percent of the V/Q volunteers.

A pulmonary embolism was missed in just 0.4 percent of those who had CTPA versus 1 percent of those who had V/Q scanning, according to the study.

"We did confirm that the newer modality (CTPA) was at least as safe as V/Q," said Anderson.

And, although doctors may still be debating which clots need immediate treatment, Glassroth said the good news from this study is that "we have ever-improving capabilities for detecting clots."

More information

To learn more about pulmonary embolism, visit the National Heart, Lung, and Blood Institute.



SOURCES: David Anderson, M.D., professor, medicine, and head, division of hematology, Dalhousie University and Capitol Health, Halifax, Nova Scotia, Canada; Jeffrey Glassroth, M.D., vice dean, chief academic officer, and professor, medicine, Feinberg School of Medicine, Northwestern University, Chicago; Dec. 19, 2007, Journal of the American Medical Association


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. European directive will halt use of MRI scans; cancer diagnosis and treatment will suffer
2. PET scans can accurately detect a breast tumors response to chemotherapy
3. High-tech CT scans: not a bad choice to test for clogged arteries
4. New Computerized Scans Effective for Spotting Clogged Arteries
5. PET scans useful for some cancer treatment, but how do patients fare?
6. PET Scans Can Spot Cervical Cancers Return
7. Post-treatment PET scans can reassure cervical cancer patients
8. CT scans to determine heart disease in the emergency room
9. Obesity Keeps Patients From Needed CT Scans After Surgery
10. PET Scans Could Boost Lung Cancer Diagnosis
11. Rise in CT Scans Poses Cancer Risk
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
CT Scans Catch More Clots in Lungs
(Date:2/11/2016)... ... ... Image One USA veteran franchise owner Maria Bogacki is bringing ... Nashville that will benefit. , “I’ve enjoyed being a part of the Image One ... question that I would bring my business with me,” Bogacki said. “The entire Image ...
(Date:2/11/2016)... ... February 11, 2016 , ... The ... among the top five firms in the “2015/2016 Best in KLAS: Software and ... Staffing. KLAS is a research and insights firm on a global mission to ...
(Date:2/11/2016)... FL (PRWEB) , ... February 11, 2016 , ... ... and advocates will discuss how to improve care by making data on heart ... heart disease. The Summit on Transparency and Public Reporting of Pediatric and Congenital ...
(Date:2/11/2016)... ... February 11, 2016 , ... ... Surgery, Dallas plastic surgeon , Dr. Rod J. Rohrich, and colleagues, examine ... Dr. Rohrich outlines recommendations for rhinoplasty surgeons when addressing this vital area. , ...
(Date:2/11/2016)... ... February 11, 2016 , ... veEDIS Clinical ... technology, with highly adaptable algorithms, has been updated to help Emergency Department physicians ... symptoms consistent with Zikas and a travel history to affected regions, or potential ...
Breaking Medicine News(10 mins):
(Date:2/11/2016)... 2016 Potrero Medical, Inc., the developer of the ... appointment of George M. Rapier, III , MD, to ... , WellMed is one of the nation,s largest physician ... members in Texas and ... his own internal medicine practice, he has been instrumental to ...
(Date:2/11/2016)... AAIPharma Services Corp./Cambridge Major Laboratories, Inc. ... development services for the pharmaceutical and biotechnology industries, ... in its Charleston, SC ... recent investments. Charleston ... with small-scale lyophilization. The site has invested in ...
(Date:2/11/2016)... SEOUL, South Korea , Feb. 11, 2016 Wearable posture tracker, ALEX , has ... project fully funded and just seven days left to go, ALEX is said to be delivered to ... http://photos.prnewswire.com/prnh/20160211/332248 ... ... ...
Breaking Medicine Technology: