Navigation Links
CROI -- Day 3: Selected highlights of NIH-supported research
Date:3/1/2011

The 18th Conference on Retroviruses and Opportunistic Infections is being held at the Hynes Convention Center in Boston from February 27 through March 2. Day three of this major HIV/AIDS research conference included the following selected presentations from scientists supported by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.

iPrEx Update

Robert M. Grant, M.D., of the J. David Gladstone Institutes in San Francisco, presented an update on the results of the iPrEx study. As reported in November 2010, this placebo-controlled clinical trial found that daily oral Truvada (tenofivir plus emtricitabine) was safe and 44 percent effective at preventing HIV infection in the nearly 2,500 HIV-negative gay and bisexual men and transgender women in the trial.

iPrEx Bone Density Study

Kathleen Mulligan, Ph.D., of the University of California, San Francisco, presented the findings of the DEXA study, which examined the effects of daily oral Truvada on bone mineral density using data from a subgroup of 503 participants enrolled in the iPrEx study. The DEXA study found small but significant decreases in bone mineral density among the individuals who took daily Truvada compared with those who took a placebo pill. Given the known association between tenofovir and decreases in the bone mineral density of HIV-infected individuals taking this antiretroviral therapy, the new finding can help scientists begin to determine whether the cause of the observed effect on bone mass is tenofovir, the virus, a host-virus interaction or other factors.

Monkey Studies of Innate Immunity

Vanessa Hirsch, D.V.M., D.Sc., of NIAID in Bethesda, Md., described how variations in the TRIM5 gene affect the level of simian immunodeficiency virus (SIV), the monkey counterpart of HIV, in rhesus macaques infected with sooty mangabey-derived SIV (SIVsm). SIVsm is a strain commonly used in animal model studies of vaccine candidates. Rhesus macaques can have five different forms of TRIM5 that vary in the degree to which they control virus replication. Dr. Hirsch reported how variations in the TRIM5 protein potentially influence the observed protective effects of vaccine candidates tested in rhesus macaques that are challenged with SIVsm.


'/>"/>

Contact: Laura Sivitz Leifman
niaidnews@niaid.nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases
Source:Eurekalert

Related medicine news :

1. Nurse-Attorney/Former Bristol-Myers Squibb Executive Selected To Lead New Jersey State Nurses Association
2. Keenan Chief Strategy Officer Selected to Join Editorial Board of Payers & Providers
3. The Icebox of Atlanta Selected as T-shirt Vendor for 3 Major Divisions of American Cancer Society's Relay For Life
4. Nurtur Is Selected By Keenan & Associates as Exclusive Provider of Disease Management Programs
5. Small Time Company Rolls into the Big League: Trigger Point Performance Therapy Selected to Attend Athletes' Performance NFL Combine Preparation Program
6. Rajesh Khanna, MD Selected as One of America's Top Ophthalmologist
7. DC Dermatologist Dr. Susan T. Elliott Selected Best Doctor by Washingtonian Magazine
8. PrescriptionDrugs.com and Mike “Zappy” Zapolin Have Been Selected to Compete in Harvard Business School New Venture Contest
9. Dr. Rajesh Khanna Selected as Best Lasik Surgeon Two Years in a Row
10. R. Shane Jackson Selected as Panelist for Center for Health Transformation Member Meeting
11. Phoseon Technology Selected as Finalist for 2010 TechAmerica Oregon Technology Awards
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/5/2016)... ... 2016 , ... Derrin Doty Group has unveiled the latest charity campaign in ... west of Seattle. The insurance provider’s caring team has been so moved by the ... to complications from the flu, that they have decided to extend their original campaign. ...
(Date:5/5/2016)... Portland, Oregon (PRWEB) , ... May 05, 2016 ... ... the Student American Chiropractic Association (SACA) is slated to host the 2016 National ... chance for all current SACA national officers and chapter officers to come together ...
(Date:5/5/2016)... (PRWEB) , ... May 05, 2016 , ... Vitenas Cosmetic ... Healthcare Design Awards, presented by the American Institute of Architects and the Academy of ... by the renowned Perkins+Will and Harrell Architects, opened to patients in October of 2014. ...
(Date:5/5/2016)... ... May 05, 2016 , ... Dr. Benjamin Stong of Kalos Facial ... treatment. Dr. Stong is double board certified and the only facial plastic surgeon ... of hair loss. Non-surgical therapies such as stem cells can be used to provide ...
(Date:5/5/2016)... ... ... In honor of National Nurses Week 2016, Aya Healthcare , the ... thank a nurse who's made a difference in their life. From Friday, May 6 ... of San Diego/Imperial Counties (up to $10,000) every time someone tells them via social ...
Breaking Medicine News(10 mins):
(Date:5/4/2016)... an upgrade. There are many medical recorders on the market but none like this. ... HD  offers unparalleled connectivity and functionality.  Ampronix  is a renowned authorized reseller of the ... Photo - http://photos.prnewswire.com/prnh/20160503/363416 ... ... ...
(Date:5/4/2016)... New Jersey , May 4, 2016 ... its successful completion of an alternative public offering (APO). ... wholly owned operating company, Valeritas, Inc. and a private ... common stock at $5.00 per share. Under ... on May 3, 2016, Valeritas Holdings, Inc. will trade ...
(Date:5/4/2016)... 2016 Research and ... Acute lymphocytic Leukemia Market and Competitive Landscape ...      (Logo: http://photos.prnewswire.com/prnh/20160330/349511LOGO ... Market and Competitive Landscape Highlights 2016, provides ... products, Acute Lymphocytic Leukemia epidemiology, Acute Lymphocytic ...
Breaking Medicine Technology: