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COUP-TFII sparks prostate cancer progression
Date:11/28/2012

enhances prostate tumor progression. Further studies in mice that lost PTEN showed that high levels of COUP-TFII promoted the metastatic spread of the prostate cancer.

Studies in cell cultures and in human tissues confirmed the activity of COUP-TFII in promoting a more aggressive form of prostate cancer that could spread and metastasize.

The next step is find out how to inhibit COUP-TFII and prevent so-called indolent prostate cancers from becoming more aggressive, said Ming-Jer Tsai.


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Contact: Dipali Pathak
pathak@bcm.edu
713-713-4710
Baylor College of Medicine
Source:Eurekalert

Page: 1 2

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